Quinine hydrochloride

Product Name: Quinine hydrochloride
CAS No.: 130-89-2
Chemical Name: Quinine hydrochloride
Synonyms: QUININE HC;QUININE HCL;chinimetten;quininemuriate;quininechloride;Quinine Impurity 11;Quinine hydrochlorid;QUININE HYDROCHLORIDE;Quinine HCL & Sulfate;QUININE HCL USP/EP/BP
CBNumber: CB2453521
Molecular Formula: C20H25ClN2O2
Formula Weight: 360.88
MOL File: 130-89-2.mol

More

Less

Quinine hydrochloride Property

Melting point:: 158-160 C
Density: 1.1206 (rough estimate)
refractive index: 1.5400 (estimate)
FEMA: 2976 | QUININE HYDROCHLORIDE
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Ethanol (1g/1ml), glycerol(1g/7ml), chloroform(1g/1ml)
form: Solid
color: White
Water Solubility: 549.7mg/L(25 ºC)
InChI: InChI=1/C20H24N2O2.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H/t13-,14-,19-,20+;/s3
InChIKey: LBSFSRMTJJPTCW-QJLYHTAINA-N
SMILES: C12C=C(C=CC=1N=CC=C2[C@@H](O)[C@]1([H])C[C@]2([H])CCN1C[C@@H]2C=C)OC.Cl |&1:10,12,15,21,r|
LogP: 3.496 (est)
EPA Substance Registry System: Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8.alpha.,9R)- (130-89-2)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
RIDADR: 1544
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29392000
Toxicity: cat,LDLo,intravenous,80mg/kg (80mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 327, 1927.

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 4114
Product name: Quininehydrochloride
Packaging: 50
Price: $53
Updated: 2021/12/16

TRC

Product number: Q694020
Product name: QuinineHydrochloride
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 256384
Product name: Quinine hydrochloride
Packaging: 50mg
Price: $267
Updated: 2021/12/16

AK Scientific

Product number: I951
Product name: QuinineHCl
Packaging: 1g
Price: $14
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0024401
Product name: QUININE HYDROCHLORIDE
Purity: 95.00%
Packaging: 10G
Price: $179.55
Updated: 2021/12/16

More

Less

Quinine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Quinine hydrochloride is a white, silky, glittering needles; odourless, effloresces when exposed to warm air. Soluble in water, very soluble in ethanol, freely soluble in chloroform, insoluble in ether. Its solutions are neutral or alkaline to litmus. It is an alkaloid derived from the bark of the cinchona tree. Quinine Hydrochloride is used as ingredient of beverages and injection medication.

Uses

Quinine Hydrochloride is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Definition

Quinine Hydrochloride is the hydrochloride of a natural substance, quinine, obtained from the bark of various species of Cinchona including Cinchona succirubra, Pavon. (red cinchona); Cinchona officinalis, Linn; Cinchona calizaya, Wenddell; Cinchona ledgeriana, Moens. It is a nature-derived bitter flavoring agent for tonic water, among other beverages.

Biological Activity

Quinine hydrochloride is a displays antimalarial and muscle relaxant properties. Stereoisomer of quinidine; closely related to chloroquine.?

Safety Profile

Poison by ingestion, subcutaneous, intravenous, intramuscular, and intraperitoneal routes. Human systemic effects by intravenous route: convulsions or effect on seizure threshold, muscle contraction or spasticity, and nausea or vomiting. Mutation data reported. Used as a local anesthetic. When heated to decomposition it emits very toxic fumes of NO, and HCI. See also QUININE.

Synthesis

Manufacture of quinine by extraction from Cinchona bark and subsequent purification and synthesis to quinine hydrochloride.

target

Adrenergic Receptor

storage

Store at -20°C

Quinine hydrochloride Preparation Products And Raw materials

Raw materials

Cinchona ledgeriana bark Quinine

Preparation Products

More

Less

Quinine hydrochloride Suppliers

Belgium 1 China 130 Europe 1 France 1 Germany 2 India 27 United Kingdom 4 United States 13 USA 1 Global 180

Chengdu rongchuangyiheng Biomedical Technology Co., Ltd

Tel: 13438025684
Email: 28296972@qq.com
Country: China
ProdList: 129
Advantage: 58

xi'an renyang Biotechnology Co., Ltd.

Tel: 13299086402
Email: renyangbiotech@163.com
Country: China
ProdList: 80
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

More

Less

View Lastest Price from Quinine hydrochloride manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: QUININE HCL 130-89-2
Price: US $10.00-8.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-10-28

Hebei Yanxi Chemical Co., Ltd.

Product: Quinine hydrochloride 130-89-2
Price: US $20.00-15.00/kg
Min. Order: 1kg
Purity: 99.5（%）
Supply Ability: 5000kg/month
Release date: 2024-03-27

Hebei Chuanghai Biotechnology Co,.LTD

Product: Quinine hcl 130-89-2
Price: US $60.00/KG
Min. Order: 1KG
Purity: 99.9%
Supply Ability: 100000kg
Release date: 2024-08-27

130-89-2, Quinine hydrochlorideRelated Search:

Quinidine Cinchonidine Quinine sulfate dihydrate Quinine Quinine dihydrochloride N-BENZYLQUININIUM CHLORIDE Quinine QUININE HCL QUININE HCL / DIHCL / SULFATE Quinine HCl medical grade QUININE HCL USP(CRM STANDARD) Quinine hydrochloride QUININE HCL NON-KOSHER 6-METHOXYCINCHONINE UREA HYDROCHLORIDE togal

QUININE HCL

QUININE HYDROCHLORIDE

QUININE MONOHYDROCHLORIDE

6’-methoxy-,monohydrochloride,(8.alpha.,9R)-Cinchonan-9-ol

6’-methoxy-,monohydrochloride,(8-alpha,9r)-cinchonan-9-o

6’-methoxy-,monohydrochloride,(8alpha,9theta)-cinchonan-9-o

chinimetten

quininechloride

quininemuriate

Hydrochloric acid quinine

Quinine·hydrochloric acid

Quinine HCL & Sulfate

Cinchonan-9-ol,6'-Methoxy-, hydrochloride (1:1), (8alpha,9R)-

(8alpha,9R)-6'-methoxycinchonan-9-ol monohydrochloride

QUININE HYDROCHLORIDE 2 H2O

Cinchonan-9-ol, 6-methoxy-, monohydrochloride, (8.alpha.,9R)-

Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, (8a,9R)- (9CI)

Quinine, monohydrochloride (8CI)

(R)-[(4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol:hydrochloride

Cinchonan-9-ol, 6'-methoxy-, hydrochloride (1:1), (8α,9R)-

Quinine Hydrochloride HCL

QUININE HCL USP/EP/BP

(R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol hydrochloride

Quinine hydrochlorid

(R)-[(2S，4S，5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol hydrochloride

QUININE HC

Quinine Impurity 11

Cyproconazole Impurity 3

130-89-2

C10H24N2O22H2O

C20H24N2O2HCl

C20H25N2O2Cl