ChemicalBook > CAS DataBase List > P-TOLUENESULFONYL FLUORIDE

P-TOLUENESULFONYL FLUORIDE

Product Name
P-TOLUENESULFONYL FLUORIDE
CAS No.
455-16-3
Chemical Name
P-TOLUENESULFONYL FLUORIDE
Synonyms
TOSYL FLUORIDE;p-Fluorosulfonyltoluene;4-TOLUENESULONYLCHLORIDE;4-Toluensulfonyl fluoride;P-TOLUENESULFONYL FLUORIDE;4-TOLUENESULFONYL FLUORIDE;toluene-4-sulfonylfluoride;4-TOLUENESULPHONYL FLUORIDE;P-TOLUENESULPHONYL FLUORIDE;toluene-p-sulphonylfluoride
CBNumber
CB2454821
Molecular Formula
C7H7FO2S
Formula Weight
174.19
MOL File
455-16-3.mol
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P-TOLUENESULFONYL FLUORIDE Property

Melting point:
41-42 °C(lit.)
Boiling point:
112 °C16 mm Hg(lit.)
Density 
1.2768 (estimate)
Flash point:
222 °F
storage temp. 
Storage temp. 2-8°C
form 
solid
Appearance
White to off-white Solid
Water Solubility 
Hydrolyzes in water.
Sensitive 
Moisture Sensitive
BRN 
2208423
Exposure limits
ACGIH: TWA 2.5 mg/m3
NIOSH: IDLH 250 mg/m3
CAS DataBase Reference
455-16-3(CAS DataBase Reference)
EPA Substance Registry System
Benzenesulfonyl fluoride, 4-methyl- (455-16-3)
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Safety

Hazard Codes 
C
Risk Statements 
20/21/22-34
Safety Statements 
22-26-27-36/37/39-45
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
RTECS 
XT8050000
Hazard Note 
Corrosive
TSCA 
T
HazardClass 
8
PackingGroup 
II
HS Code 
29049095
Toxicity
rat,LD50,intraperitoneal,200mg/kg (200mg/kg),Nature. Vol. 173, Pg. 33, 1954.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
117455
Product name
p-Toluenesulfonyl fluoride
Purity
98%
Packaging
10g
Price
$53.48
Updated
2025/07/31
TCI Chemical
Product number
M3518
Product name
4-Methylbenzenesulfonyl Fluoride
Purity
min. 98.0 %
Packaging
5G
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
M3518
Product name
4-Methylbenzenesulfonyl Fluoride
Purity
min. 98.0 %
Packaging
25G
Price
$232
Updated
2025/07/31
SynQuest Laboratories
Product number
6762-3-X1
Product name
4-Toluenesulfonyl fluoride
Purity
98%
Packaging
25g
Price
$125
Updated
2021/12/16
SynQuest Laboratories
Product number
6762-3-X1
Product name
4-Toluenesulfonyl fluoride
Purity
98%
Packaging
5G
Price
$60
Updated
2021/12/16
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P-TOLUENESULFONYL FLUORIDE Chemical Properties,Usage,Production

Chemical Properties

White to beige fused mass

Uses

p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimer?s disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.

Uses

Protease inhibitor.

General Description

p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.

reaction suitability

reaction type: click chemistry

P-TOLUENESULFONYL FLUORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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P-TOLUENESULFONYL FLUORIDE Suppliers

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View Lastest Price from P-TOLUENESULFONYL FLUORIDE manufacturers

Career Henan Chemical Co
Product
P-TOLUENESULFONYL FLUORIDE 455-16-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%HPLC
Supply Ability
10 tons/month
Release date
2020-01-07

455-16-3, P-TOLUENESULFONYL FLUORIDERelated Search:

P-TOLUENESULFINIC ACID p-Toluenesulfonic acid p-Toluenesulfonic acid monohydrate toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester BENZENESULFONYL FLUORIDE Phenylmethylsulfonyl fluoride 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride P-TOLUENESULFONYL FLUORIDE 5'-P-FLUOROSULFONYL-BENZOYLADENOSINE HYDROCHLORIDE SULFORHODAMINE B 5-ACID FLUORIDE 4-(FLUOROSULFONYL)BENZOYL CHLORIDE 4-(FLUOROSULFONYL)BENZOIC ACID 4-(CHLOROMETHYL)BENZENESULPHONYL FLUORIDE 2,4,6-TRIMETHYLBENZENESULFONYL FLUORIDE 4-Fluorosulfonyl-3-methoxy-benzoic acid 4-(2-HYDROXY-1,1-DIMETHYL-ETHYL)-BENZENESULFONYL FLUORIDE SULFORHODAMINE Q 5-ACID FLUORIDE 4'-METHYLBIPHENYL-4-SULFONYLFLUORIDE

  • 4-TOLUENESULPHONYL FLUORIDE
  • 4-TOLUENESULFONYL FLUORIDE
  • 4-METHYLBENZENESULFONYL FLUORIDE
  • P-TOLUENESULFONYL FLUORIDE
  • P-TOLUENESULPHONYL FLUORIDE
  • TOSYL FLUORIDE
  • 4-methyl-benzenesulfonylfluorid
  • p-Fluorosulfonyltoluene
  • Tosyl fluoride, 4-Methylbenzenesulphonyl fluoride
  • p-Toluenesulfonyl fluoride, 97% 5GR
  • Toluene-4-sulphonyl fluoride 98%
  • p-Toluenesulfonyl fluoride 98%
  • 4-Toluensulfonyl fluoride
  • p-methylbenzenesulfonylfluoride
  • p-methylphenylsulfonylfluoride
  • toluene-4-sulfonylfluoride
  • toluene-p-sulphonylfluoride
  • para-toluenesulfonyl fluoride
  • p-Toluenesulfonylfluoride,98%
  • 4-Toluenesulphonyl fluoride 98%
  • 4-Toluenesulphonylfluoride98%
  • 4-TOLUENESULONYLCHLORIDE
  • 4-Toluensulfonyl fluoride, GC 98%
  • p-Toluenesulfonic acid fluoride
  • p-Toluenesulfonyl fluoride,97%
  • Benzenesulfonyl fluoride, 4-methyl-
  • <i>p</i>-Toluenesulfonyl fluoride
  • Toluene-4-sulphonyl fluoride
  • 455-16-3
  • CH3C6H4SO2F
  • Sulfur Compounds
  • Sulfonyl Halides
  • Organic Building Blocks
  • Building Blocks
  • Organic Building Blocks
  • Sulfonyl Halides
  • Sulfur Compounds