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17-PHENYL TRINOR PGF2ALPHA-IPR

Product Name
17-PHENYL TRINOR PGF2ALPHA-IPR
CAS No.
130209-76-6
Chemical Name
17-PHENYL TRINOR PGF2ALPHA-IPR
Synonyms
13-trans-Latanoprost;Sparsentan Impurity 17;Bimatoprost isopropyl este;imatoprost isopropyl ester;Bimatoprost isopropyl ester;17-PHENYL TRINOR PGF2ALPHA-IPR;Bimatoprost Acid Isopropyl Ester;17-phenyl trinor PGF2α isopropyl ester;17-phenyl trinor PGF2alpha isopropyl ester;17-phenyl trinor Prostaglandin F2α isopropyl ester
CBNumber
CB2459437
Molecular Formula
C26H38O5
Formula Weight
430.58
MOL File
130209-76-6.mol
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17-PHENYL TRINOR PGF2ALPHA-IPR Property

Boiling point:
573.4±50.0 °C(Predicted)
Density 
1.141
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 1 mg/ml
pka
14.25±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16824
Product name
17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity
≥98%
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
16824
Product name
17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity
≥98%
Packaging
5mg
Price
$324
Updated
2024/03/01
Cayman Chemical
Product number
16824
Product name
17-phenyl trinor Prostaglandin F2α isopropyl ester
Purity
≥98%
Packaging
10mg
Price
$575
Updated
2024/03/01
AHH
Product number
MT-21382
Product name
17-PhenyltrinorPgf2alpha-Ipr
Purity
98%
Packaging
0.01g
Price
$345
Updated
2021/12/16
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17-PHENYL TRINOR PGF2ALPHA-IPR Chemical Properties,Usage,Production

Description

17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost. This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist. In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative was examined for IOP-lowering activity during the development of latanoprost. At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester was the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative was also significantly more irritating to the eye than latanoprost.

Uses

PhDH 100A can be useful in the determination of prostaglandin analogs in cosmetic products by high performance liquid chromatography with tandem mass spectrometry.

Definition

ChEBI: 17-phenyl-trinor-PGF2alpha isopropyl ester is a prostanoid.

17-PHENYL TRINOR PGF2ALPHA-IPR Preparation Products And Raw materials

Raw materials

Preparation Products

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17-PHENYL TRINOR PGF2ALPHA-IPR Suppliers

Canada 1 China 40 India 2 Switzerland 1 United Kingdom 1 United States 6 USA 1 Global 52
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
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View Lastest Price from 17-PHENYL TRINOR PGF2ALPHA-IPR manufacturers

Career Henan Chemical Co
Product
17-PHENYL TRINOR PGF2ALPHA-IPR 130209-76-6
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200KG
Release date
2019-07-01

130209-76-6, 17-PHENYL TRINOR PGF2ALPHA-IPRRelated Search:

(Z)-7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-((E)-(S)-3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-HEPT-5-ENOIC ACID METHYL ESTER 17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA 17-PHENYL TRINOR PGF2ALPHA-IPR

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  • 9ALPHA,11ALPHA,15S-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
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  • (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-5-heptenoic acid propan-2-yl ester
  • 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic acid 1-methylethyl ester
  • Bimatoprost isopropyl ester
  • 17-phenyl trinor Prostaglandin F2α isopropyl ester
  • 17-phenyl trinor PGF2α isopropyl ester
  • isopropyl 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((S,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
  • propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoate
  • Bimatoprost isopropyl este
  • imatoprost isopropyl ester
  • 17-phenyl trinor PGF2alpha isopropyl ester
  • Bimatoprost Acid Isopropyl Ester
  • 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-
  • 13-trans-Latanoprost
  • isopropyl phenylhydroxypentene dihydroxycyclopentylheptenate
  • 17-phenyl trinor Prostaglandin F2α isopropyl ester
  • Sparsentan Impurity 17
  • 130209-76-6
  • C26H38O5