ChemicalBook > CAS DataBase List > MM-589 TFA salt
MM-589 TFA salt
- Product Name
- MM-589 TFA salt
- CAS No.
- 2097887-21-1
- Chemical Name
- MM-589 TFA salt
- Synonyms
- MM-589 (TFA);MM-589 TFA salt;MM589 TFA,MM 589 TFA
- CBNumber
- CB24675387
- Formula Weight
- 0
- MOL File
- Mol file
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MM-589 TFA salt Property
- storage temp.
- -20°C, away from moisture
- solubility
- DMSO : 25 mg/mL (36.40 mM; ultrasonic and warming and heat to 60°C)
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0069689
- Product name
- MM-589TFA
- Purity
- 98.76%
- Packaging
- 1mg
- Price
- $1200
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0069689
- Product name
- MM-589TFA
- Purity
- 98.76%
- Packaging
- 2mg
- Price
- $1800
- Updated
- 2021/12/16
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MM-589 TFA salt Chemical Properties,Usage,Production
Biological Activity
MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interactions. MM-MM-589 TFA binds WDR5 with an IC50 of 0.90 nM. IC50 for inhibition of MLL H3K4 methyltransferase activity is 12.7 nM.
in vitro
MM-589 TFA (0.01-10 μM, 4 days or 7 days) potently and selectively inhibits cell growth in human leukemia cell lines harboring MLL translocations.
Cell Viability Assay < table class="zh_use_1"> < tr>
| Cell Line: | MV4-11 and MOLM-13 cells |
| Concentration: | 0.01, 0.1, 1, 10 μM |
| Incubation Time: | 4 days or 7 days |
| Result: | Potently inhibited MV4-11 and MOLM-13 cell growth with IC 50 s of 0.25 and 0.21 μM, respectively. Had much weaker activity in the inhibition of cell growth of the HL-60 cell line with an IC 50 of 8.6 μM. |
target
IC50: 0.90 nM (WDR5), 12.7 nM (HMT)
Ki: <1 nM (WDR5)
MM-589 TFA salt Preparation Products And Raw materials
Raw materials
Preparation Products
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MM-589 TFA salt Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@medchemexpress.com
- Country
- United States
- ProdList
- 6398
- Advantage
- 58
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View Lastest Price from MM-589 TFA salt manufacturers
Wuhan Xinhao Biotechnology Co., Ltd
- Product
- MM-589 TFA 2097887-21-1
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2024-01-15