6-Bromo-2-naphthoic acid
- Product Name
- 6-Bromo-2-naphthoic acid
- CAS No.
- 5773-80-8
- Chemical Name
- 6-Bromo-2-naphthoic acid
- Synonyms
- RAVI-001;6-Bromo-2-naphthoic;6-BROMO-2-NAPHTHALENE;6-Bromo-2-phthoic acid;6-BROMO-2-NAPHTHOIC ACID;6-BROMO-2-NAPHTHIOC ACID;6-BROMO-2-NAPHTHOLIC AICD;6-BROMO-2-NAPHTHOLIC ACID;6-Bromo-2-naphthoicacid,96%;6-BROMO-2-NAPHTHOIC ACID 99%
- CBNumber
- CB2467951
- Molecular Formula
- C11H7BrO2
- Formula Weight
- 251.08
- MOL File
- 5773-80-8.mol
6-Bromo-2-naphthoic acid Property
- Melting point:
- 294-295°C
- Boiling point:
- 387.3±17.0 °C(Predicted)
- Density
- 1.648±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- powder to crystal
- pka
- 4.06±0.30(Predicted)
- color
- White to Light yellow
- Water Solubility
- Insoluble in water.
- BRN
- 2328940
- InChI
- InChI=1S/C11H7BrO2/c12-10-4-3-7-5-9(11(13)14)2-1-8(7)6-10/h1-6H,(H,13,14)
- InChIKey
- NPMCAVBMOTZUPD-UHFFFAOYSA-N
- SMILES
- C1=C2C(C=C(Br)C=C2)=CC=C1C(O)=O
- CAS DataBase Reference
- 5773-80-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-36
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- CDS004635
- Product name
- 6-Bromo-2-naphthoic acid
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 100 mg
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- B3823
- Product name
- 6-Bromo-2-naphthoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $51
- Updated
- 2025/07/31
- Product number
- B3823
- Product name
- 6-Bromo-2-naphthoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $201
- Updated
- 2025/07/31
- Product number
- B685930
- Product name
- 6-Bromo-2-napthoicAcid
- Packaging
- 25g
- Price
- $695
- Updated
- 2021/12/16
- Product number
- 55061
- Product name
- 6-Bromo-2-napthoicAcid
- Packaging
- 25g
- Price
- $1200
- Updated
- 2021/12/16
6-Bromo-2-naphthoic acid Chemical Properties,Usage,Production
Chemical Properties
Pale brown solid
Uses
Benzimidazole derivatives has been prepared by using ortho-phenyl diamine and 6-bromo-2-naphthoic acid.
Synthesis
33626-98-1
5773-80-8
Methyl 6-bromo-2-naphthalenecarboxylate (3b) (2.7 g, 10.0 mmol) was used as a raw material to form a suspension with potassium hydroxide (1.1 g, 20.0 mmol) in methanol (50 mL) at 50 °C with vigorous stirring. At the beginning of the reaction, the suspension gradually changed to a homogeneous solution, indicating that the raw material was completely consumed. After the reaction lasted for 8 hours, about 2/3 of the volume of solvent was removed by evaporation under reduced pressure. Subsequently, water (1500 mL) was added to the residue and the unreacted esters were extracted with ethyl acetate. The aqueous phase was acidified to pH 3 with 10% H2SO4 and subsequently extracted with ethyl acetate (3 x 200 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give pure 6-bromo-2-naphthalenecarboxylic acid (3a) (2.1 g, 8.4 mmol, 84% yield). The melting point of the product was 290-294 °C (decomposition). High resolution mass spectrum (ESI+): m/z [M + 1]+ calculated value (C11H8BrO2) was 252.08591, measured value was 252.08582. 1H NMR (DMSO-d6) δ= 7.72 (1H, dd, J = 8.5 and 1.8 Hz, 7-naphthalenyl H), 7.99 (1H, d, J = 8.6 Hz, 4-naphthalenyl H) ), 8.02 (1H, dd, J = 8.6 and 1.4 Hz, 8-naphthalenyl H), 8.09 (1H, d, J = 8.8 Hz, 3-naphthalenyl H), 8.30 (1H, d, J = 1.6 Hz, 5-naphthalenyl H), 8.62 (1H, s, 1-naphthalenyl H), and 13.15 (1H, br.s, COOH).13C NMR ( 125.76 MHz, DMSO-d6) δ= 121.93, 126.50, 127.61, 128.81, 129.83, 130.01, 130.64, 130.90, 131.63, 136.11, 167.30.
References
[1] Organic and Biomolecular Chemistry, 2015, vol. 13, # 27, p. 7477 - 7486
[2] Organic and Biomolecular Chemistry, 2015, vol. 13, # 27, p. 7477 - 7486
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 4, p. 1557 - 1568
[4] Bioorganic Chemistry, 2011, vol. 39, # 4, p. 151 - 158
[5] Patent: US2012/88746, 2012, A1. Location in patent: Page/Page column 47-48
6-Bromo-2-naphthoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
6-Bromo-2-naphthoic acid Suppliers
- Tel
- --
- Fax
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- Sales@casorganic.com
- Country
- Ukraine
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- 5026
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View Lastest Price from 6-Bromo-2-naphthoic acid manufacturers
- Product
- 6-Bromo-2-naphthoic acid 5773-80-8
- Price
- US $2.00-5.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons
- Release date
- 2025-07-10
- Product
- 6-Bromo-2-naphthoic acid 5773-80-8
- Price
- US $0.00/KG
- Min. Order
- 10KG
- Purity
- 98%min
- Supply Ability
- 500kg/month
- Release date
- 2023-01-09
- Product
- 6-Bromo-2-naphthoic acid 5773-80-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-12