ChemicalBook > CAS DataBase List > (2S,4R)-4-METHYLGLUTAMIC ACID

(2S,4R)-4-METHYLGLUTAMIC ACID

Product Name
(2S,4R)-4-METHYLGLUTAMIC ACID
CAS No.
31137-74-3
Chemical Name
(2S,4R)-4-METHYLGLUTAMIC ACID
Synonyms
SYM 2081;(2S,4R)-4-MethylglutamicAci;(2S-R)-4-METHYLGLUTAMIC ACID;(2S,4R)-4-METHYLGLUTAMIC ACID;(4R)- 4-Methyl-L-glutamic Acid;L-erythro--Methylglutamic Acid;erythro-L-4-Methylglutamic Acid;ERYTHRO-4-METHYL-L-GLUTAMIC ACID;L-Glutamic acid, 4-methyl-, (4R)-;(2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP
CBNumber
CB2468367
Molecular Formula
C6H11NO4
Formula Weight
161.16
MOL File
31137-74-3.mol
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(2S,4R)-4-METHYLGLUTAMIC ACID Property

Melting point:
178 °C
Boiling point:
287.44°C (rough estimate)
Density 
1.3482 (rough estimate)
refractive index 
1.4230 (estimate)
storage temp. 
Store at RT
solubility 
H2O: >10 mg/mL
form 
solid
pka
2.34±0.21(Predicted)
color 
white
CAS DataBase Reference
31137-74-3(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
0903
Product name
SYM2081
Purity
≥97%(HPLC)
Packaging
10
Price
$214
Updated
2021/12/16
TRC
Product number
M311575
Product name
(2S,4R)-4-MethylglutamicAcid
Packaging
50mg
Price
$1050
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0000080
Product name
(2S,4R)-4-METHYL GLUTAMIC ACID
Purity
95.00%
Packaging
5MG
Price
$209
Updated
2021/12/16
ApexBio Technology
Product number
B6497
Product name
SYM2081
Packaging
5mg
Price
$410
Updated
2021/12/16
ChemScene
Product number
CS-0021132
Product name
SYM2081
Purity
>97.0%
Packaging
5mg
Price
$450
Updated
2021/12/16
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(2S,4R)-4-METHYLGLUTAMIC ACID Chemical Properties,Usage,Production

Chemical Properties

White

Uses

A highly selective and potent agonist for kainate receptors.

Biological Activity

Potent and highly selective kainate receptor agonist, with an IC 50 for inhibition of [ 3 H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™ and Kainate Receptor Tocriset™ .

(2S,4R)-4-METHYLGLUTAMIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S,4R)-4-METHYLGLUTAMIC ACID Suppliers

Canada 1 China 45 Germany 1 Japan 1 Switzerland 3 Ukraine 1 United Kingdom 5 United States 13 USA 1 Global 71
Suzhou Chenrui Biotechnology Co. LTD
Tel
17625585511
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qq：1580084073
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1580084073@qq.com
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China
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
ProdList
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
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3bsc@sina.com
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China
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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ShangHai Caerulum Pharma Discovery Co., Ltd.
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18149758185 18149758185
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sales-cpd@caerulumpharma.com
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China
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Suzhou yacoo science co.,Ltd
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0512-87182056 18013166090
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0512-87182056
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lingling.qi@yacoo.com.cn
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China
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Shanghai Lollane Biological Technology Co.,Ltd.
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021-52996696，15000506266 15000506266
Fax
+86-21-52996696
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China
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4566
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EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
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Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
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China
ProdList
9806
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Shanghai Chaolan Chemical Technology Center
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021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7290
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31137-74-3, (2S,4R)-4-METHYLGLUTAMIC ACIDRelated Search:

(2S,1'S,2'S)-2-(CARBOXYCYCLOPROPYL)GLYCINE D,L-2-METHYLGLUTAMIC ACID HEMIHYDRATE, 9 9%,DL-2-METHYLGLUTAMIC ACID,DL-methylglutamic acid hemihydrate Z-L-GLA(OTBU)2-OH (1S,3R)-ACPD DCG IV L-TRANS-PYRROLIDINE-2,4-DICARBOXYLIC ACID 4-DIMETHYL-L-GLUTAMIC ACID 1-AMINOCYCLOBUTANE-CIS-1,3-DICARBOXYLIC ACID H-GLA-OH LY 341495 L-CIS-PYRROLIDINE-2,4-DICARBOXYLIC ACID (+/-)-1-AMINOCYCLOPENTANE-CIS-1,3-DICARBOXYLIC ACID (2S,4R)-4-METHYLGLUTAMIC ACID (2S,3R,4S)-CCG FMOC-GLA(OTBU)2-OH (2S,4S)-4-METHYLGLUTAMIC ACID HYDROCHLORIDE D-2-Methylglutamic acid (2R,3R)-3-Methylglutamic acid

  • SYM 2081
  • ERYTHRO-4-METHYL-L-GLUTAMIC ACID
  • (2S,4R)-(+)-2-Amino-4-methylpentanedioic acid
  • (2S,4R)-4-METHYLGLUTAMIC ACID
  • (2S,4R)-(+)-2-AMINO-4-METHYLPENTANEDIOIC ACID 99%
  • (2S-R)-4-METHYLGLUTAMIC ACID
  • (4R)- 4-Methyl-L-glutamic Acid
  • erythro-L-4-Methylglutamic Acid
  • L-erythro--Methylglutamic Acid
  • (2S,4R)-(+)-2-Amino-4-methylpentanedioic acid,99%
  • L-Glutamic acid, 4-methyl-, (4R)-
  • (2S,4R)-4-MethylglutamicAci
  • (2S,4R)-4-METHYLGLUTAMIC ACID USP/EP/BP
  • 31137-74-3
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Ionotropic Glutamate Receptor Modulators
  • Ion Channels
  • Ligand-Gated Ion Channels
  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
  • Chiral Reagents
  • Neurochemicals