ChemicalBook > CAS DataBase List > 4-Hydroxydiphenylamine

4-Hydroxydiphenylamine

Product Name
4-Hydroxydiphenylamine
CAS No.
122-37-2
Chemical Name
4-Hydroxydiphenylamine
Synonyms
vti1;VTI2;VTI 1;VTI1L;VTI1L1;v-SNARE;vti1-rp1;VTI1-LIKE;4-ANILINOPHENOL;P-ANILINOPHENOL
CBNumber
CB2470708
Molecular Formula
C12H11NO
Formula Weight
185.22
MOL File
122-37-2.mol
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4-Hydroxydiphenylamine Property

Melting point:
67-73°C
Boiling point:
190°C
Density 
1.0936 (rough estimate)
refractive index 
1.5300 (estimate)
Flash point:
209°C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Ethanol: Soluble: =10 mg/mlPBS (pH 7.2): Soluble: =10 mg/ml
form 
powder to lump
pka
10.46±0.13(Predicted)
color 
Gray, solid leaflets
BRN 
511942
InChI
InChI=1S/C12H11NO/c14-12-8-6-11(7-9-12)13-10-4-2-1-3-5-10/h1-9,13-14H
InChIKey
JTTMYKSFKOOQLP-UHFFFAOYSA-N
SMILES
C1(O)=CC=C(NC2=CC=CC=C2)C=C1
CAS DataBase Reference
122-37-2(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 4-(phenylamino)-(122-37-2)
EPA Substance Registry System
Phenol, 4-(phenylamino)- (122-37-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
37/38-41-22-21
Safety Statements 
26-36/37/39-36/39
RIDADR 
UN2811
RTECS 
SJ6950000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29222990
Toxicity
LD50 oral in rat: 3300mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H318Causes serious eye damage

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S579025
Product name
4-HYDROXYDIPHENYLAMINE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$185
Updated
2025/07/31
Sigma-Aldrich
Product number
S579025
Product name
4-HYDROXYDIPHENYLAMINE
Purity
Aldrich
Packaging
1g
Price
$179
Updated
2024/03/01
TCI Chemical
Product number
A0470
Product name
4-Hydroxydiphenylamine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$67
Updated
2025/07/31
TCI Chemical
Product number
A0470
Product name
4-Hydroxydiphenylamine
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$715
Updated
2025/07/31
TRC
Product number
H941750
Product name
4-Hydroxydiphenylamine
Packaging
10g
Price
$55
Updated
2021/12/16
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4-Hydroxydiphenylamine Chemical Properties,Usage,Production

Uses

4-Hydroxydiphenylamine is used as a reactant in the preparation of iron methylisopropylglyoxime dimethylpyridine/dimethylaminopyridine/phenylaminophenol/imidazolidone complexes.

Definition

Gray solid leaflets. Insoluble in water; soluble in alcohol, ether, acetone, chloroform, alkali, and benzene.

Hazard

Irritant.

Safety Profile

Poison by intravenous route.Moderately toxic by ingestion. A severe eye irritant. Seealso AROMATIC AMINES. When heated todecomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the amine from chlorobenzene/pet ether, pentane (m 72o) or *C6H6/pet ether (m 70o). [Beilstein 13 III 1019, 13 IV 1052.]

References

[1] HAOQI NINA ZHAO, EDWARD P. KOLODZIEJ*; Transformation Products of Tire Rubber Antioxidant 6PPD in Heterogeneous Gas-Phase Ozonation: Identification and Environmental Occurrence[J]. Environmental Science and Technology, 2023, 57 14: 5621-5632. DOI: 10.1021/acs.est.2c08690
[2] NICO GRASSE, THORSTEN REEMTSMA*; Uptake and Biotransformation of the Tire Rubber-derived Contaminants 6-PPD and 6-PPD Quinone in the Zebrafish Embryo (Danio rerio)[J]. Environmental Science and Technology, 2023, 57 41: 15598-15607. DOI: 10.1021/acs.est.3c02819
[3] W E ALEXANDER; S E W; A J Ryan. Metabolism of diphenylamine in the rat, rabbit and man.[J]. Food and cosmetics toxicology, 1965, 3 4: 571-579. DOI: 10.1016/s0015-6264(65)80203-6
[4] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.

4-Hydroxydiphenylamine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxydiphenylamine Suppliers

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View Lastest Price from 4-Hydroxydiphenylamine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-Hydroxydiphenylamine 122-37-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-26
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Hydroxydiphenylamine 122-37-2
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-05
Career Henan Chemical Co
Product
4-Hydroxydiphenylamine 122-37-2
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-22

122-37-2, 4-Hydroxydiphenylamine Related Search:

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  • Phenol, p-anilino-
  • Phenol,4-(phenylamino)-
  • Phenyl-p-aminophenol
  • p-Hydroxydifenylamin
  • p-Oxydiphenylamine
  • VTI 1
  • 4-Hydroxydiphenylamine &gt
  • 4-Hydroxydiphenylamine ISO 9001：2015 REACH
  • 4-HYDROXY DIPHENYLAMINE (PEDIA)
  • 4-Hydroxydiphenylamine, ≥ 95.0%
  • v-SNARE
  • VTI1L
  • VTI1L1
  • VTI1-LIKE
  • vti1-rp1
  • VTI2
  • 122-37-2
  • AMINE
  • Anilines, Aromatic Amines and Nitro Compounds
  • ADVANCED INT.