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(+/-)-BAY K 8644

Product Name
(+/-)-BAY K 8644
CAS No.
93468-89-4
Chemical Name
(+/-)-BAY K 8644
Synonyms
BAY K-8644 (+/-);(+/-)-BAY K 8644;(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem;(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
CBNumber
CB2471785
Molecular Formula
C16H15F3N2O4
Formula Weight
356.3
MOL File
93468-89-4.mol
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(+/-)-BAY K 8644 Property

Melting point:
166-172 °C
storage temp. 
2-8°C
solubility 
DMSO: 184 mg/mL
form 
Yellow solid
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Safety

Hazard Codes 
Xi
Risk Statements 
36/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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(+/-)-BAY K 8644 Chemical Properties,Usage,Production

Definition

ChEBI: Methyl 2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-3-carboxylate is a pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6. It is a dihydropyridine, a methyl ester, a C-nitro compound and a member of (trifluoromethyl)benzenes.

General Description

Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration.

Biochem/physiol Actions

Primary TargetL-type Ca2+ channel

(+/-)-BAY K 8644 Preparation Products And Raw materials

Raw materials

Preparation Products

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(+/-)-BAY K 8644 Suppliers

China 49 Japan 2 Switzerland 2 United Kingdom 5 United States 6 Global 64
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93468-89-4, (+/-)-BAY K 8644Related Search:

(+/-) CAGED BAY K 8644 R(+)-BAY K 8644, CALCIUM CHANNEL R(+)-BAY K 8644,R(+)-BAY K 8644 CA2(+) CHANNEL BLOCKE,(+/-)-BAY K 8644, 0 TO 5 °C,R(+)-BAY K 8644 98% 0 C S(-)-BAY K 8644,S(-)-BAY K 8644 CA2+ CHANNEL ACTIVATO R(+)-BAY K 8644 CALCIUM CHANNEL (RS)-BAY K 8644,(+/-)-BAY K 8644,BAY K-8644 (+/-),(+/-)-BAY K8644 CALCIUM SLOW CHANNEL (+-)-CAGED BAY K 8644

  • 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
  • 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER
  • 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER
  • (+/-)-BAY K 8644
  • BAY K-8644 (+/-)
  • (+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid
  • (±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem
  • 93468-89-4
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