O-PHOSPHORYLETHANOLAMINE
- Product Name
- O-PHOSPHORYLETHANOLAMINE
- CAS No.
- 1071-23-4
- Chemical Name
- O-PHOSPHORYLETHANOLAMINE
- Synonyms
- Pe 104;NSC 254167;NSC 25416);PHOSPHOCOLAMINE;Fosforilcolamine;O-PHOSPHOCOLAMINE;Colamine phosphate;Phsophorilcolamine;O-PHOSPHOCHOLAMINE;PHOSPHORYL COLAMINE
- CBNumber
- CB2478380
- Molecular Formula
- C2H8NO4P
- Formula Weight
- 141.06
- MOL File
- 1071-23-4.mol
O-PHOSPHORYLETHANOLAMINE Property
- Melting point:
- 241-243 °C(lit.)
- Boiling point:
- 335.8±44.0 °C(Predicted)
- Density
- 1.554±0.06 g/cm3(Predicted)
- storage temp.
- Store below +30°C.
- Water Solubility
- Soluble in water
- solubility
- PBS (pH 7.2): 10 mg/ml
- form
- powder to crystal
- pka
- pK1:5.838(+1);pK2:10.638(0) (25°C)
- color
- White to Light yellow
- BRN
- 1758916
- InChIKey
- SUHOOTKUPISOBE-UHFFFAOYSA-N
- CAS DataBase Reference
- 1071-23-4(CAS DataBase Reference)
- EPA Substance Registry System
- Ethanol, 2-amino-, dihydrogen phosphate (ester) (1071-23-4)
Safety
- Hazard Codes
- T,C
- Risk Statements
- 25-34
- Safety Statements
- 26-36/37/39-45-27
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- RTECS
- KJ5830000
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29221990
- Toxicity
- LD50 orally in Rabbit: 5820 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- P0503
- Product name
- O-Phosphorylethanolamine
- Packaging
- 1g
- Price
- $22.7
- Updated
- 2024/03/01
- Product number
- P0503
- Product name
- O-Phosphorylethanolamine
- Packaging
- 5g
- Price
- $34.5
- Updated
- 2024/03/01
- Product number
- 8.20061
- Product name
- 2-Aminoethyl dihydrogen phosphate
- Purity
- for synthesis
- Packaging
- 10g
- Price
- $53.9
- Updated
- 2024/03/01
- Product number
- 8.20061
- Product name
- 2-Aminoethyl dihydrogen phosphate
- Purity
- for synthesis
- Packaging
- 50g
- Price
- $168
- Updated
- 2024/03/01
- Product number
- 73104
- Product name
- O-Phosphorylethanolamine
- Purity
- certified reference material, TraceCERT?
- Packaging
- 100MG
- Price
- $101
- Updated
- 2022/05/15
O-PHOSPHORYLETHANOLAMINE Chemical Properties,Usage,Production
Chemical Properties
O-PHOSPHORYLETHANOLAMINE is white powder
Uses
O-PHOSPHORYLETHANOLAMINEe is used in the synthesis of Sphingomyelin, a type of sphingolipid found in animal cell membrane.
Uses
O-Phosphorylethanolamine has been used:
- in LHC-8 medium as a supplement in culturing the transformed human liver epithelial (THLE)-2 and THLE-3 cells
- in C-reactive protein (CRP) binding sucrose flotation experiment
- to incubate phosphomonoesters with anion-exchange chromatography (AEC) fractions for the detection of phosphatase activity
- to add in the washed beads for the preparation of phosphorylethanolamine (Pet) -conjugated sepharose column for chromatographic purification of mutant CRP
Definition
ChEBI: The ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain.
Biochem/physiol Actions
Phosphorylethanolamine participates in phospholipid metabolism. Its release can be stimulated occasionally by depolarizing stimuli. Reduction of phosphorylethanolamine levels has been observed in Alzheimer′s and Huntington′s disease.
Purification Methods
Purification by recrystallisation from aqueous EtOH gives a hydrate (m 140-141o). Its solubility in H2O is 17% and 0.003% in MeOH or EtOH at 22o. [F.lisch & .sterberg J Biol Chem 234 2298 1959, Baer & Staucer Can J Chem 34 434 1956, Christensen J Biol Chem 135 399 1940.] It is a potent inhibitor of ornithine decarboxylase [Gilad & Gilad Biochem Biophys Res Commun 122 277 1984]. [Beilstein 4 IV 1415.]
O-PHOSPHORYLETHANOLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
O-PHOSPHORYLETHANOLAMINE Suppliers
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View Lastest Price from O-PHOSPHORYLETHANOLAMINE manufacturers
- Product
- O-PHOSPHORYLETHANOLAMINE 1071-23-4
- Price
- US $36.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-16
- Product
- O-PHOSPHORYLETHANOLAMINE 1071-23-4
- Price
- US $1.00/PCS
- Min. Order
- 1PCS
- Purity
- 99%
- Supply Ability
- 100mt
- Release date
- 2024-11-01
- Product
- O-phosphorylethanolamine 1071-23-4
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-09