AST2818 mesylate
- Product Name
- AST2818 mesylate
- CAS No.
- 2130958-55-1
- Chemical Name
- AST2818 mesylate
- Synonyms
- Alflutinib mesylate;Furmonertinib;AST2818 mesylate;ASK120067 mesylate;Furmonertinib mesylate;Alflutinib methanesulfonate;Alflutinib mesylate (AST2818);Alflutinib (AST2818 mesylate);Alflutinib mesylate (Furmonertinib);N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate
- CBNumber
- CB24797023
- Molecular Formula
- C29H35F3N8O5S
- Formula Weight
- 664.71
- MOL File
- 2130958-55-1.mol
AST2818 mesylate Property
- storage temp.
- Store at -20°C,unstable in solution, ready to use.
- solubility
- Chloroform: 10 mg/ml; DMF: slightly soluble; DMSO: slightly soluble
- form
- A crystalline solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0067492
- Product name
- AST2818mesylate
- Purity
- 99.99%
- Packaging
- 5mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- CS-0067492
- Product name
- AST2818mesylate
- Purity
- 99.99%
- Packaging
- 10mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- CS-0067492
- Product name
- AST2818mesylate
- Purity
- 99.99%
- Packaging
- 50mg
- Price
- $850
- Updated
- 2021/12/16
- Product number
- CS-0067492
- Product name
- AST2818mesylate
- Purity
- 99.99%
- Packaging
- 100mg
- Price
- $1250
- Updated
- 2021/12/16
- Product number
- orb573198
- Product name
- Alflutinib mesylate (AST2818)
- Packaging
- 100mg
- Price
- $1283.5
- Updated
- 2021/12/16
AST2818 mesylate Chemical Properties,Usage,Production
Description
Furmonertinib (formerly known as alflutinib) is another me-too third-generation EGFR TKI that has a pyridyl ring replacing the phenyl ring of osimertinib and a trifluoroethyl group replacing the methyl group (Fig. 4). This TKI, which was discovered and developed by Shanghai Allist Pharma, was approved in November 2019 by the NMPA of China for the second-line treatment of NSCLC with EGFR sensitive mutation and EGFR T790M drug-resistant mutation, and more recently as a first-line treatment for classical EGFR mutant NSCLC. In June 2022, furmonertinib was granted the Fast Track designation by the FDA in patients with advanced or metastatic NSCLC with activating EGFR or HER2 mutations, including exon 20 insertion mutations.
AST2818 mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
AST2818 mesylate Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32161
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58
- Tel
- support@targetmol.com
- Country
- United States
- ProdList
- 38631
- Advantage
- 58
- Tel
- --
- Fax
- --
- cayman@caymanchem.com
- Country
- United States
- ProdList
- 6213
- Advantage
- 81
View Lastest Price from AST2818 mesylate manufacturers
- Product
- AST2818 mesylate 2130958-55-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26