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Methylprednisolone aceponate

Product Name
Methylprednisolone aceponate
CAS No.
86401-95-8
Chemical Name
Methylprednisolone aceponate
Synonyms
SH-440;Advantan;ZK-91588;ZK-91-588;Aceponate;ZK-91588：SH-440;Prednisolone Impurity 21;METHYLPREDNISOLONE ACEPONATE;Methilprednisolone aceponate;Methylprednisolone Impurity 55
CBNumber
CB2483146
Molecular Formula
C27H36O7
Formula Weight
472.57
MOL File
86401-95-8.mol
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Methylprednisolone aceponate Property

Melting point:
105 - 108°C
Boiling point:
595.8±50.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Ethyl Acetate(Slightly)
pka
14.05±0.70(Predicted)
form 
Solid
color 
White to Off-White
InChIKey
DALKLAYLIPSCQL-TXWHWSFMNA-N
SMILES
O(C(CC)=O)[C@]1(C(COC(C)=O)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(C=C[C@]4(C)[C@H]3[C@H](C[C@]12C)O)=O |&1:5,15,16,18,25,27,28,30,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M325725
Product name
6α-MethylPrednisoloneAceponate
Packaging
250mg
Price
$785
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0003341
Product name
METHYLPREDNISOLONE ACEPONATE
Purity
95.00%
Packaging
25MG
Price
$716.1
Updated
2021/12/16
Matrix Scientific
Product number
093984
Product name
Methylprednisolone aceponate
Purity
95+%
Packaging
250mg
Price
$756
Updated
2021/12/16
AK Scientific
Product number
K542
Product name
Methylprednisoloneaceponate
Packaging
250mg
Price
$1070
Updated
2021/12/16
Matrix Scientific
Product number
093984
Product name
Methylprednisolone aceponate
Purity
95+%
Packaging
1g
Price
$1647
Updated
2021/12/16
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Methylprednisolone aceponate Chemical Properties,Usage,Production

Description

Methylprednisolone aceponate (MPA) is a new potent topical corticosteroid. Chemically, it is a corticosteroid diester that penetrates the skin rapidly. It is rapidly metabolised and then conjugated, so although potent, it does not appear to cause serious local or systemic side effects. Clinical trials have shown that once daily use is sufficient to control most eczematous conditions and is also appropriate and effective in atopic dermatitis. MPA is effective in the treatment of facial and scalp eczema and sunburn and has shown promising results in the treatment of psoriasis. MPA is also suitable for use in children and infants. MPA is available in a wide range of formulations (0.1%) including creams, ointments, fat ointments, lotions and solutions depending on the patient's individual condition.

Uses

Methylprednisolone aceponate used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.

Definition

ChEBI: Methylprednisolone aceponate is a corticosteroid hormone.

Trade name

ADVANTAN?

Side effects

The most common side effects of Methylprednisolone aceponate (MPA) include itching and burning sensation. Other rare side effects are skin infection at the application site, redness, swelling or irritation at the application site, skin infection or the appearance of small blood vessels on the surface, stretch marks, acne, infection of the hair follicles at the application site, excessive growth of unwanted hair, discolouration of the skin and allergic reactions. If any serious adverse reaction occurs, contact your doctor promptly.

Methylprednisolone aceponate Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Methylprednisolone Praseodymium(III) nitrate hexahydrate

Preparation Products

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Methylprednisolone aceponate Suppliers

Canada 1 China 91 China Hong Kong 1 Europe 1 Germany 1 India 9 United Kingdom 5 United States 15 Global 124
Finetech Industry Limited
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CR Corporation Limited
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Finetech Industry Limited
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View Lastest Price from Methylprednisolone aceponate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Methylprednisolone aceponate 86401-95-8
Price
US $0.00/Kg/Bag
Min. Order
10g
Purity
98%-102%
Supply Ability
10kgs
Release date
2021-08-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
Methylprednisolone aceponate 86401-95-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26
Hebei shuoxi biotechnology co. LTD
Product
Methylprednisolone aceponate 86401-95-8
Price
US $60.00/KG
Min. Order
1g
Purity
99.8%
Supply Ability
10tons
Release date
2019-10-25

86401-95-8, Methylprednisolone aceponate Related Search:

Prednisone Prednisolone Prednisolone phosphate sodium CHLOROPHOSPHONAZO III Methylprednisolone acetate Prednisolone-21-acetate Methylprednisolone Methylprednisolone hemisuccinate 6alpha-Methylprednisolone sodium succinate 2,2-Bis(hydroxymethyl)propionic acid EPDM RUBBER Meprednisone Deprodone 1,3-DIACETOXYACETONE Methylprednisolone aceponate

  • [(6s,8r,9r,10s,11s,13s,14s,17r)-17-(2-acetyloxyacetyl)-11-hydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthren-17-yl] propanoate
  • METHYLPREDNISOLONE ACEPONATE
  • Advantan
  • ZK-91588：SH-440
  • 11β-Hydroxy-6α-methyl-21-acetoxy-17-(propionyloxy)pregna-1,4-diene-3,20-dione
  • 21-(Acetyloxy)-11β-hydroxy-6α-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • SH-440
  • ZK-91588
  • ZK-91-588
  • 6α-Methyl Prednisolone Aceponate
  • 6alpha-Methylprednisolone aceponate
  • (6α，11β)-21-(Aeetoxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)pregna-14-dien-3，20-dione
  • Aceponate
  • Methilprednisolone aceponate
  • (6S,8S,9S,10R,11S,13S,14S,17R)-17-(2-Acetoxyacetyl)-11-hydroxy-6,10,13-triMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate
  • Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-11-hydroxy-6-Methyl-17-(1-oxopropoxy)-, (6a,11b)-
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6α,11β)-
  • Methylprednisolone aceponate Solution in Acetonitrile, 1000μg/mL
  • Prednisolone Impurity 21
  • Methylprednisolone AceponateQ: What is Methylprednisolone Aceponate Q: What is the CAS Number of Methylprednisolone Aceponate
  • Methylprednisolone Impurity 55
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy)-, (6α,11β)-
  • 86401-95-8
  • C27H36O7
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • Steroid and Hormone