Azido-PEG8-CH2CO2-PFP
- Product Name
- Azido-PEG8-CH2CO2-PFP
- CAS No.
- 2182601-80-3
- Chemical Name
- Azido-PEG8-CH2CO2-PFP
- Synonyms
- Azido-PEG8-CH2COO-PFP;Azido-PEG8-CH2CO2-PFP
- CBNumber
- CB24849546
- Molecular Formula
- C24H34F5N3O10
- Formula Weight
- 619.54
- MOL File
- 2182601-80-3.mol
Azido-PEG8-CH2CO2-PFP Property
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-23816
- Product name
- Azido-PEG8-CH2CO2-PFP
- Purity
- 98%
- Packaging
- 100mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-23816
- Product name
- Azido-PEG8-CH2CO2-PFP
- Purity
- 98%
- Packaging
- 250mg
- Price
- $580
- Updated
- 2021/12/16
Azido-PEG8-CH2CO2-PFP Chemical Properties,Usage,Production
Description
Azido-PEG8-CH2CO2-PFP is a monodisperse PEG molecule thathas an azide group and a PFP group. The azide group enable Click Chemistry reactions with alkynes. The PFP group can react with amines to form stable bonds. PFP moieties are also less susceptible to undergo hydrolysis. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains enhance the water solubility properties of the chain.
Uses
Azido-PEG8-CH2COO-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG8-CH2COO-PFP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG8-CH2CO2-PFP Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG8-CH2CO2-PFP Suppliers
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- 0431-0431-80514535 19917294565
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- China
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View Lastest Price from Azido-PEG8-CH2CO2-PFP manufacturers
- Product
- Azido-PEG8-CH2COO-PFP 2182601-80-3
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-23