N3-PEG5-CH2COOH

Product Name: N3-PEG5-CH2COOH
CAS No.: 217180-81-9
Chemical Name: N3-PEG5-CH2COOH
Synonyms: N3-PEG5-CH2COOH;N3-PEG5-CH2CO2H;Azido-PEG5-CH2CO2H;AZIDE-PEG5-CH2COOH;Azido-PEG5-CH2COOH;17-azido-3,6,9,12,15-pentaoxaheptadecanoic acid;2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
CBNumber: CB43354351
Molecular Formula: C12H23N3O7
Formula Weight: 321.33
MOL File: 217180-81-9.mol

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N3-PEG5-CH2COOH Property

storage temp.: -20°C, protect from light
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23813
Product name: Azido-PEG5-CH2CO2H
Purity: 98%
Packaging: 500mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-23813
Product name: Azido-PEG5-CH2CO2H
Purity: 98%
Packaging: 1g
Price: $570
Updated: 2021/12/16

Activate Scientific

Product number: AS103619
Product name: N3-PEG5-CH2COOH
Purity: 95+%
Packaging: 1g
Price: $588
Updated: 2021/12/16

Acrotein

Product number: AC-8206
Product name: N3-PEG5-CH2COOH
Purity: 97%
Packaging: 1g
Price: $495
Updated: 2021/12/16

purepeg

Product number: 437505
Product name: N3-PEG5-CH2COOH
Purity: min.97%
Packaging: 1g
Price: $504
Updated: 2021/12/16

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N3-PEG5-CH2COOH Chemical Properties,Usage,Production

Description

Azido-PEG5-CH2CO2H is a water soluble PEG linker. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide.

Uses

Azido-PEG5-CH2CO2H is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG5-CH2CO2H is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-CH2CO2H is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

Cleavable Linker; PEGs

References

[1] Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

N3-PEG5-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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N3-PEG5-CH2COOH Suppliers

China 42 United States 4 Global 46

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5872
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3935
Advantage: 55

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10110
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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Shanghai Yihe Biological Technology Co., Ltd.

Tel: 021-68882955 17721395025
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Country: China
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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
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UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
Fax: 021-58958618
Email: sales@uhnshanghai.com
Country: China
ProdList: 1984
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Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1615
Advantage: 58

217180-81-9, N3-PEG5-CH2COOHRelated Search:

Cyclohexanone oxime Azido-PEG5-CH2CO2-PFP N3-PEG8-CH2COOH Azido-PEG8-CH2CO2-PFP

Azido-PEG5-CH2COOH

AZIDE-PEG5-CH2COOH

N3-PEG5-CH2COOH

Azido-PEG5-CH2CO2H

N3-PEG5-CH2CO2H

17-azido-3,6,9,12,15-pentaoxaheptadecanoic acid

2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

217180-81-9

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