ChemicalBook > CAS DataBase List > 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE

4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE

Product Name
4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
CAS No.
6345-27-3
Chemical Name
4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
Synonyms
4-AmidinopyridiniumHCl;Pyridin-4-carboximidamide HCl;IsonicotiniMidaMide hydrochloride;4-Amidinopyridinium chloride, 98+%;4-pyridin-carbamidine hydrochloride;4-pyridinecarboxamidine hydrochloride;4-AMIDINOPYRIDINE HYDROCHLORIDE, 98+%;4-Amidinopyridine hydrochloride ydrochloride;4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE;Pyridine-4-carboximidamide hydrochloride, 4-Carbamimidoylpyridine hydrochlo
CBNumber
CB2500438
Molecular Formula
C12H16Cl2N6
Formula Weight
315.20164
MOL File
6345-27-3.mol
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4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Property

Melting point:
240-242°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
White to off-white Solid
Sensitive 
Hygroscopic
BRN 
3562678
InChI
InChI=1S/2C6H7N3.2ClH/c2*7-6(8)5-1-3-9-4-2-5;;/h2*1-4H,(H3,7,8);2*1H
InChIKey
YXRVCYDHRUUPFU-UHFFFAOYSA-N
SMILES
C1N=CC=C(C(=N)N)C=1.[H]Cl.C1N=CC=C(C(N)=N)C=1.[H]Cl
CAS DataBase Reference
6345-27-3
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37
Hazard Note 
Irritant
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
P840418
Product name
Pyridine-4-carboximidamideHydrochloride
Packaging
100mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
C182
Product name
4-Amidinopyridiniumhydrochloride
Packaging
100g
Price
$427
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK621783
Product name
4-Amidinopyridinehydrochloride
Purity
98%
Packaging
1g
Price
$28
Updated
2021/12/16
SynQuest Laboratories
Product number
3H41-5-X1
Product name
Pyridine-4-carboxamidine hydrochloride
Packaging
5G
Price
$44
Updated
2021/12/16
SynQuest Laboratories
Product number
3H41-5-X1
Product name
Pyridine-4-carboxamidine hydrochloride
Packaging
1g
Price
$16
Updated
2021/12/16
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4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Synthesis

100-48-1

6345-27-3

The general procedure for the synthesis of 4-formamidopyridine hydrochloride from 4-cyanopyridine was as follows: 4-cyanopyridine (20.0 g, 0.2 mol) was dissolved in anhydrous methanol (200 mL), followed by a one-time addition of powdered sodium methanol (1.1 g, 20 mmol). The reaction mixture was stirred at room temperature overnight. Next, ammonium chloride (16.5 g, 0.31 mol) was added and the reaction mixture was heated to reflux for 4 hours, after which it was cooled to room temperature. The solvent was removed by evaporation, anhydrous ethanol (300 mL) was added, and the mixture was subsequently heated to reflux. after 15 min, the solid insoluble material was removed by filtration, and the filtrate was cooled to room temperature and allowed to stand overnight. The filtrate was filtered again to remove additional inorganic salts and finally the reaction mixture was concentrated to about one-third of the original volume, which was filtered to give 24.0 g of 4-formamidinopyridine hydrochloride in 76% yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 15, p. 3487 - 3490
[2] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 11, p. 3347 - 3356
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 12, p. 2990 - 2993
[4] Journal of Medicinal Chemistry, 1990, vol. 33, # 4, p. 1230 - 1241
[5] Patent: US5294612, 1994, A

4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Suppliers

China 75 France 1 Germany 4 India 3 Switzerland 1 United Kingdom 7 United States 16 Global 107
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View Lastest Price from 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE 6345-27-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-08

6345-27-3, 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDERelated Search:

Benzamidine hydrochloride PYRIDINE-2-CARBOXAMIDE 3-(2-PYRIDYL)ACRYLIC ACID Pyridine hydrofluoride 2,4-Pyridinedicarboxylic acid, 2-Methyl ester 4-METHYLPHTHALIMIDE Formamidine hydrochloride 4-PYRIDINECARBOXAMIDINE 4-AMIDINOPYRIDINIUM CHLORIDE Pyridine-2-carboximidamide hydrochloride 3-AMIDINOPYRIDINIUM CHLORIDE

  • 4-AMIDINOPYRIDINE HYDROCHLORIDE, 98+%
  • 4-pyridin-carbamidine hydrochloride
  • IsonicotiniMidaMide hydrochloride
  • Pyridine-4-carboximidamide hydrochloride, 4-Carbamimidoylpyridine hydrochloride, Pyridine-4-carboxamidine hydrochloride
  • 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
  • 4-Amidinopyridinium chloride, 98+%
  • 4-AmidinopyridiniumHCl
  • 4-pyridinecarboxamidine hydrochloride
  • Pyridine-4-carboximidamide hydrochloride, 4-Carbamimidoylpyridine hydrochlo
  • 4-Amidinopyridine hydrochloride ydrochloride
  • Pyridin-4-carboximidamide HCl
  • 6345-27-3
  • C6H10ClN3O