4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
- Product Name
- 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
- CAS No.
- 6345-27-3
- Chemical Name
- 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE
- Synonyms
- 4-AmidinopyridiniumHCl;Pyridin-4-carboximidamide HCl;IsonicotiniMidaMide hydrochloride;4-Amidinopyridinium chloride, 98+%;4-pyridin-carbamidine hydrochloride;4-pyridinecarboxamidine hydrochloride;4-AMIDINOPYRIDINE HYDROCHLORIDE, 98+%;4-Amidinopyridine hydrochloride ydrochloride;4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE;Pyridine-4-carboximidamide hydrochloride, 4-Carbamimidoylpyridine hydrochlo
- CBNumber
- CB2500438
- Molecular Formula
- C12H16Cl2N6
- Formula Weight
- 315.20164
- MOL File
- 6345-27-3.mol
4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Property
- Melting point:
- 240-242°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to off-white Solid
- Sensitive
- Hygroscopic
- BRN
- 3562678
- InChI
- InChI=1S/2C6H7N3.2ClH/c2*7-6(8)5-1-3-9-4-2-5;;/h2*1-4H,(H3,7,8);2*1H
- InChIKey
- YXRVCYDHRUUPFU-UHFFFAOYSA-N
- SMILES
- C1N=CC=C(C(=N)N)C=1.[H]Cl.C1N=CC=C(C(N)=N)C=1.[H]Cl
- CAS DataBase Reference
- 6345-27-3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- P840418
- Product name
- Pyridine-4-carboximidamideHydrochloride
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 3H41-5-X1
- Product name
- Pyridine-4-carboxamidine hydrochloride
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
- Product number
- JK621783
- Product name
- 4-Amidinopyridinehydrochloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $28
- Updated
- 2021/12/16
- Product number
- 3H41-5-X1
- Product name
- Pyridine-4-carboxamidine hydrochloride
- Packaging
- 5G
- Price
- $44
- Updated
- 2021/12/16
- Product number
- 9985CH
- Product name
- Isonicotinimidamidehydrochloride
- Packaging
- 5g
- Price
- $97
- Updated
- 2021/12/16
4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
White powder
Synthesis
100-48-1
6345-27-3
The general procedure for the synthesis of 4-formamidopyridine hydrochloride from 4-cyanopyridine was as follows: 4-cyanopyridine (20.0 g, 0.2 mol) was dissolved in anhydrous methanol (200 mL), followed by a one-time addition of powdered sodium methanol (1.1 g, 20 mmol). The reaction mixture was stirred at room temperature overnight. Next, ammonium chloride (16.5 g, 0.31 mol) was added and the reaction mixture was heated to reflux for 4 hours, after which it was cooled to room temperature. The solvent was removed by evaporation, anhydrous ethanol (300 mL) was added, and the mixture was subsequently heated to reflux. after 15 min, the solid insoluble material was removed by filtration, and the filtrate was cooled to room temperature and allowed to stand overnight. The filtrate was filtered again to remove additional inorganic salts and finally the reaction mixture was concentrated to about one-third of the original volume, which was filtered to give 24.0 g of 4-formamidinopyridine hydrochloride in 76% yield.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 15, p. 3487 - 3490
[2] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 11, p. 3347 - 3356
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 12, p. 2990 - 2993
[4] Journal of Medicinal Chemistry, 1990, vol. 33, # 4, p. 1230 - 1241
[5] Patent: US5294612, 1994, A
4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE Suppliers
- Tel
- 0512-69209928 18796809688
- zhouyingxiang@highfine.com
- Country
- China
- ProdList
- 1356
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 86-21-63210123
- Fax
- 86-21-63290778 86-21-63218885
- sj_scrc@sinopharm.com
- Country
- China
- ProdList
- 9815
- Advantage
- 79
- Tel
- 800-810-5118
- Fax
- +86-10-84193589
- cnchemical@thermofisher.com
- Country
- China
- ProdList
- 17770
- Advantage
- 75
- Tel
- info@aonanchem.com
- Country
- China
- ProdList
- 65
- Advantage
- 55
View Lastest Price from 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE manufacturers
- Product
- 4-AMIDINOPYRIDINE HYDROCHLORIDEPYRIDINE-4-CARBOXIMIDAMIDE HYDROCHLORIDE 6345-27-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-08