ChemicalBook > CAS DataBase List > ACETOPHENAZINE MALEATE (200 MG)

ACETOPHENAZINE MALEATE (200 MG)

Product Name
ACETOPHENAZINE MALEATE (200 MG)
CAS No.
5714-00-1
Chemical Name
ACETOPHENAZINE MALEATE (200 MG)
Synonyms
tindal;sch6673;Acetophazine maleate;ACETOPHENZAINEMALEATE;acetophenazinemaleate;Acetophenazine dimaleate;Acetophenazine dimaleate salt;ACETOPHENAZINE MALEATE (200 MG);10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-ylmethylketon;1-(10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-10h-phenothiazin-2-yl)eth
CBNumber
CB2501622
Molecular Formula
C53H64N6O11S2
Formula Weight
1025.23886
MOL File
5714-00-1.mol
More
Less

ACETOPHENAZINE MALEATE (200 MG) Property

Melting point:
167-168.5°
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
color 
Yellow to Orange
Stability:
Hygroscopic
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
RTECS 
OB4180000
Toxicity
LD50 orally in rats: 433 mg/kg (Schafer)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
A163930
Product name
AcetophenazineDimaleate
Packaging
1g
Price
$1070
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008962
Product name
ACETOPHENAZINE MALEATE
Purity
95.00%
Packaging
2G
Price
$1947
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18998
Product name
AcetophenazineDimaleate
Packaging
2g
Price
$2620
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008962
Product name
ACETOPHENAZINE MALEATE
Purity
95.00%
Packaging
1G
Price
$640.72
Updated
2021/12/16
More
Less

ACETOPHENAZINE MALEATE (200 MG) Chemical Properties,Usage,Production

Originator

Tindal ,Schering ,US ,1961

Uses

Antipsychotic.

Definition

ChEBI: A maleate salt obtained by combining acetophenazine with two molar equivalents of maleic acid.

Manufacturing Process

The requisite intermediate, 10-(3-chloropropyl)-2-acetylphenothiazineis prepared as follows: To a suspension of sodium amide (from 3 grams of sodium) in 300 ml of liquid ammonia is added 30 grams of 2- acetylphenothiazine. After stirring for one hour, there is added 19 grams of 1- bromo-3-chloropropane. The ammonia is allowed to evaporate and the residue is diluted with 200 ml of water. The mixture is extracted with ether and the ether solution is dried over anhydrous sodium sulfate, filtered and concentrated.
The residue consists of crude 10-(3-chloropropy1)-2-acetylphenothiazine as a viscous oil and is used in the next step without further purification. The crude base obtained from the reaction of 10-(3-chloropropyl)-2-acetylphenothiazine with 1-(2-hydroxyethyl)piperazine is purified by conversion to its dimaleate salt, MP 167-168.5°C from ethanol.

brand name

Tindal (Schering).

Therapeutic Function

Tranquilizer

Safety Profile

Poison by ingestion, intraperitoneal,and intravenous routes. Severe eye irritant.

ACETOPHENAZINE MALEATE (200 MG) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ACETOPHENAZINE MALEATE (200 MG) Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
Country
China
ProdList
4505
Advantage
50
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55717
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Alfa Chemistry
Tel
+1-5166625404
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
21317
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44941
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24131
Advantage
58
Shaanxi Dideu Newmaterial Co., Ltd.
Tel
029-63373950 15353716720
Email
1052@dideu.com
Country
China
ProdList
10007
Advantage
58

5714-00-1, ACETOPHENAZINE MALEATE (200 MG)Related Search:


  • Acetophenazine dimaleate salt
  • ketone,10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-ylmethyl
  • ketone,10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-ylmethyl,dimaleate
  • sch6673
  • tindal
  • ACETOPHENAZINE MALEATE (200 MG)
  • 2-acetyl-10-[3-[4-(2-hydroxyethyl)piperazinyl]propyl]-10H-phenothiazine dimaleate
  • ACETOPHENZAINEMALEATE
  • 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl methyl ketone
  • 10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl ketone dimaleate
  • 10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl]propyl]phenothiazin-2-yl methyl ketone maleate (1:2) (salt)
  • Acetophazine maleate
  • Acetophenazine dimaleate
  • Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (Z) 2-butenedioate (1:2) (salt)
  • Ethanone, 1-[10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-phenothiazin-2-yl]-, (Z)-2-butenedioate (1:2) (salt)
  • 1-(10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-10h-phenothiazin-2-yl)eth
  • 1-(2-hydroxyethyl)-4-(3-(2-acetyl-10-phenothiazinyl)propyl)piperazinedimalea
  • 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-ylmethylketon
  • 2-acetyl-10-(3-(4-(beta-hydroxyethyl)piperazinyl)propyl)phenothiazinedimalea
  • acetophenazinemaleate
  • Phenothiazine,anxious depression,psychotic disorders,inhibit,Acetophenazine dimaleate,Dopamine Receptor,schizophrenia,antipsychotic,Inhibitor
  • 5714-00-1
  • C23H29N3O2S2C4H4O4
  • C31H37N3O10S
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds