Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]-

Product Name: Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]-
CAS No.: 1664335-55-0
Chemical Name: Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]-
Synonyms: TAK-615, 10 mM in DMSO;4-((N-(Cyclopropylmethyl)-4-(2-fluorophenoxy)benzamido)methyl)benzoic acid;4-(((Cyclopropylmethyl)(4-(2-fluorophenoxy)benzoyl)amino)methyl)benzoic acid;Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]-;LPA1,fibrosis,LPL Receptor,Lysophospholipid Receptor,TAK615,modulator,TAK-615,NAM,inhibit,pulmonary,Inhibitor,allosteric,TAK 615,negative
CBNumber: CB25952281
Molecular Formula: C25H22FNO4
Formula Weight: 419.44
MOL File: 1664335-55-0.mol

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Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]- Property

Boiling point:: 607.4±55.0 °C(Predicted)
Density: 1.302±0.06 g/cm3(Predicted)
pka: 4.22±0.10(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0068718
Product name: TAK-615
Purity: 99.51%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0068718
Product name: TAK-615
Purity: 99.51%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0068718
Product name: TAK-615
Purity: 99.51%
Packaging: 25mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-0068718
Product name: TAK-615
Purity: 99.51%
Packaging: 50mg
Price: $1450
Updated: 2021/12/16

ChemScene

Product number: CS-0068718
Product name: TAK-615
Purity: 99.51%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]- Chemical Properties,Usage,Production

Uses

TAK-615 is a negative allosteric modulator (NAM) of the LPA1 receptor for the research of pulmonary fibrosis. TAK-615 binds the LPA1 receptor with high affinity (Kd high affinity of 1.7 nM and Kd low affinity of 14.5 nM)[1].

IC 50

LPA1 Receptor: 1.7-14.5 nM (Kd)

References

[1] Jonathan Ellery, et al. Identification of Compounds Acting as Negative Allosteric Modulators of the LPA 1 Receptor. Eur J Pharmacol. 2018 Aug 15;833:8-15. DOI:10.1016/j.ejphar.2018.05.040

Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]- Suppliers

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1664335-55-0, Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]-Related Search:

Mobocertinib Tak 799 TAK-960 Soticlestat TAK-632 TAK875 TAK-733 6-[(7S)-7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl]-N-methyl-2-naphthalenecarboxamide

Benzoic acid, 4-[[(cyclopropylmethyl)[4-(2-fluorophenoxy)benzoyl]amino]methyl]-

LPA1,fibrosis,LPL Receptor,Lysophospholipid Receptor,TAK615,modulator,TAK-615,NAM,inhibit,pulmonary,Inhibitor,allosteric,TAK 615,negative

TAK-615, 10 mM in DMSO

4-(((Cyclopropylmethyl)(4-(2-fluorophenoxy)benzoyl)amino)methyl)benzoic acid

4-((N-(Cyclopropylmethyl)-4-(2-fluorophenoxy)benzamido)methyl)benzoic acid

1664335-55-0