ChemicalBook > CAS DataBase List > Tak 799

Tak 799

Product Name
Tak 799
CAS No.
229005-80-5
Chemical Name
Tak 799
Synonyms
CS-2889;Tak 799;Takeda 779;TAK-779(Cl);TAK 799 ;TAK 779;TAK-779 >=98% (HPLC);TAK-779;TAK 779;TAK779;TAK779;TAK 799;TAKEDA 779;TAK-779 Chemical Structure;N,N-Dimethyl-N-(4-(2-(p-tolyl)-6,7-dihydro-5H-benzo[7]annulene-8-carboxamido)benzyl)tetrahydro-2H-pyran-4-aminium chloride
CBNumber
CB72497117
Molecular Formula
C33H39N2O2.Cl
Formula Weight
531.136
MOL File
229005-80-5.mol
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Tak 799 Property

storage temp. 
2-8°C
solubility 
H2O: soluble3mg/mL, clear (warmed)
form 
powder
color 
white to beige
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0911
Product name
TAK-779
Purity
≥98% (HPLC)
Packaging
5mg
Price
$195
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0911
Product name
TAK-779
Purity
≥98% (HPLC)
Packaging
25mg
Price
$299.2
Updated
2024/03/01
Cayman Chemical
Product number
26744
Product name
TAK-779
Packaging
1mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
26744
Product name
TAK-779
Packaging
25mg
Price
$344
Updated
2024/03/01
Cayman Chemical
Product number
26744
Product name
TAK-779
Packaging
5mg
Price
$129
Updated
2024/03/01
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Tak 799 Chemical Properties,Usage,Production

Uses

TAK-779 has been used to inhibit CC chemokine ligand 5 (CCL5)– C-C chemokine receptor type 5 (CCR5) interaction in vitro in natural killer (NK) cytotoxicity assay. It has also been used as a blocker of CCR5 to study its effects and to evaluate the opening of the Panx-1 channels on peripheral blood mononuclear cells (PBMCs) isolated from human immunodeficiency virus (HIV)-infected individuals.

Biochem/physiol Actions

TAK-779 is a potent, dual antagonist at chemokine receptors C-C chemokine receptor type 2 (CCR2) and C-C chemokine receptor type 5 (CCR5) with IC50 = 1.4 nM at CCR5 and 2.3 nM at CCR2. Antagonists of both CCR2 and CCR5 such as TAK-779 have been investigated for treatment of viruses, rheumatoid arthritis, multiple sclerosis, and cancer. CCR5 is particularly targeted for anti-HIV therapy, since HIV entry into cells requires chemokine coreceptors CCR5 and C-X-C motif chemokine receptor 4 (CXCR4).

storage

Store at -20°C

Tak 799 Preparation Products And Raw materials

Raw materials

Preparation Products

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Tak 799 Suppliers

Shanghai Dongyang Biotechnology Co., Ltd.
Tel
0512-0512-13601744364 13601744364
Email
chemsharker@126.com
Country
China
ProdList
924
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Shanghai Hekang Biotechnology Co., Ltd.
Tel
18939837085
Fax
2880152141(QQ)
Email
youchemicals@gmail.com
Country
China
ProdList
1830
Advantage
55
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4566
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55

229005-80-5, Tak 799Related Search:


  • 2H-Oyran-4-aminium, N-((4-(((6,7-dihydro-2-(4-methylphenyl)-5H-benzocyclohepten-8-yl)carbonyl)amino)phenyl)methyl)tetrahydro-N,N-dimethyl-
  • 2H-Pyran-4-aminium, N,N-dimethyl-N-(4-(((2-(4-methylphenyl)-6,7-dihydro-5H-benzocyclohepten-8-yl)carbonyl)amino)benzyl)tetrahydro-, chloride
  • N,N-Dimethyl-N-(4-(((2-(4-methylphenyl)-6,7-dihydro-5H-benzocyclohepten-8-yl)carbonyl)amino)benzyl)tetrahydro-2H-pyran-4-aminium chloride
  • Tak 799
  • Takeda 779
  • TAK 799 ;TAK 779
  • TAK779;TAK 799;TAKEDA 779
  • N,N-Dimethyl-N-[4-[[[2-(4-methylphenyl)-6,7-dihydro-5H-benzohepten-8-yl]carbonyl]amino]benzyl]tetrahydro-2H-pyran-4-aminium chloride
  • TAK-779 Chemical Structure
  • TAK-779(Cl)
  • CS-2889
  • TAK-779;TAK 779;TAK779
  • TAK-779 >=98% (HPLC)
  • TAK-779,TAK 779,CCR,HIV,Human immunodeficiency virus,Takeda779,Takeda-779,TAK779,CXCR,inhibit,CXC chemokine receptors,CC chemokine receptor,Inhibitor
  • N,N-Dimethyl-N-(4-(2-(p-tolyl)-6,7-dihydro-5H-benzo[7]annulene-8-carboxamido)benzyl)tetrahydro-2H-pyran-4-aminium chloride
  • 229005-80-5