ChemicalBook > CAS DataBase List > Piperazine-2-carboxylic acid

Piperazine-2-carboxylic acid

Product Name: Piperazine-2-carboxylic acid
CAS No.: 2762-32-5
Chemical Name: Piperazine-2-carboxylic acid
Synonyms: DS-1093;DS-1043;PRZCA-2HCL;TIMTEC-BB SBB003518;2-Piperazinecarboxyl;piperazine-2-carboxylicaci;PIPERAZINE-2-CARBOXYLIC ACID;(±)-Piperazine-2-carboxylic acid;PIPERAZINE-2-CARBOXYLIC ACID 2HCL;(^+)-Piperazine-2-carboxylic acid
CBNumber: CB2663395
Molecular Formula: C5H10N2O2
Formula Weight: 130.15
MOL File: 2762-32-5.mol

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Piperazine-2-carboxylic acid Property

Melting point:: 265 °C (dec.)(lit.)
Boiling point:: 313.6±37.0 °C(Predicted)
Density: 1.174
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 1.90±0.20(Predicted)
Appearance: White to yellow Solid
optical activity: Consistent with structure
InChI: InChI=1S/C5H10N2O2/c8-5(9)4-3-6-1-2-7-4/h4,6-7H,1-3H2,(H,8,9)
InChIKey: JSSXHAMIXJGYCS-UHFFFAOYSA-N
SMILES: N1CCNCC1C(O)=O
CAS DataBase Reference: 2762-32-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: P991853
Product name: Piperazine-2-carboxylicAcid
Packaging: 10mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-W002409
Product name: Piperazine-2-carboxylicacid
Purity: >98.0%
Packaging: 100g
Price: $61
Updated: 2021/12/16

Matrix Scientific

Product number: 074978
Product name: Piperazine-2-carboxylic acid
Purity: 95+%
Packaging: 5g
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: J98649
Product name: Piperazine-2-carboxylicacid
Packaging: 5g
Price: $10
Updated: 2021/12/16

ChemScene

Product number: CS-W002409
Product name: Piperazine-2-carboxylicacid
Purity: >98.0%
Packaging: 500g
Price: $302
Updated: 2021/12/16

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Piperazine-2-carboxylic acid Chemical Properties,Usage,Production

Uses

Piperazine-2-carboxylic acid is an important organic compound used as a basic structural component of pharmaceutical intermediates. Studies have shown that Piperazine-2-carboxylic acid derivatives are a potential multi-targeted ligands (MTDLs) anti-Alzheimer's disease (AD) active ingredient.

Synthesis

98-97-5

2762-32-5

Step 1: Preparation of piperazine-2-carboxylic acid: pyrazine-2-carboxylic acid (102.7 g, 0.827 mol) was dissolved in water (600 mL), sodium hydroxide (66 g, 1.65 mol) and 20% palladium/carbon catalyst (5.0 g) were added. The hydrogenation reaction was carried out under hydrogen atmosphere for 15 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated. Concentrated hydrochloric acid was added to the concentrate and a white precipitate precipitated. The solid was washed with cold water, collected by filtration and dried under vacuum to give 137.2 g of piperazine-2-carboxylic acid hydrochloride (99.6% yield). Mass spectrum (MS): m/z 131 (corresponding to C5H10N2O2, [M+H]+).

References

[1] Tetrahedron Letters, 1989, vol. 30, # 39, p. 5193 - 5196
[2] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 8, p. 1121 - 1126
[3] Patent: US6251919, 2001, B1

Piperazine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Piperazine-2-carboxylic acid manufacturers

Shanghai Xinchem Co., Ltd.

Product: Piperazine-2-carboxylic acid 2762-32-5
Price: US $0.00-0.00/drums
Min. Order: 1drums
Purity: 99%min.
Supply Ability: 10tons
Release date: 2023-10-22

Dideu Industries Group Limited

Product: 2-Piperazinecarboxylic acid dihydrochloride 2762-32-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-24

Career Henan Chemical Co

Product: 2-Piperazinecarboxylic acid dihydrochloride 2762-32-5
Price: US $8.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-25

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(^+)-Piperazine-2-carboxylicacid,98%

PRZCA-2HCL

(+/-)-PIPERAZINE-2-CARBOXYLIC ACID 2HCL

PIPERAZINE-2-CARBOXYLIC ACID 2HCL

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TIMTEC-BB SBB003518

Piperazine-2-carboxylic acid dihydrochloride

2-Piperazinecarboxylic acid dihydrochloride

piperazine-2-carboxylicaci

2-Piperazinecarboxylic acid dihydrochloride ISO 9001：2015 REACH

(^+)-Piperazine-2-carboxylic acid

PIPERAZINE-2-CARBOXYLIC ACID

Piperazine-2-carboxylic acid, 97%

(±)-Piperazine-2-carboxylic acid

DS-1093

DS-1043

2762-32-5