4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE

Product Name: 4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE
CAS No.: 16355-28-5
Chemical Name: 4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE
Synonyms: NSC15457;6β-Hydroxycortisone;6β-Hydroxycortisone;6-BETA-HYDROCORTISONE;6-BETA-HYDROXYCORTISONE;6B-hydroxycortisone approx. 99%;4-Pregnene-6β,17α,21-triol-3,11,20-trione;4-PREGNEN-6-β, 17,21-TRIOL-3,11,20-TRIONE;4-PREGNEN-6β, 17, 21-TRIOL-3, 11, 20-TRIONE;4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE
CBNumber: CB2672472
Molecular Formula: C21H28O6
Formula Weight: 376.44
MOL File: 16355-28-5.mol

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: H918450
Product name: 6β-Hydroxycortisone
Packaging: 5mg
Price: $180
Updated: 2021/12/16

TRC

Product number: H918450
Product name: 6β-Hydroxycortisone
Packaging: 50mg
Price: $1390
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0004696
Product name: 4-PREGNEN-6-BETA,17,21-TRIOL-3,11,20-TRIONE
Purity: 98.00%
Packaging: 0.5G
Price: $1292.5
Updated: 2021/12/16

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4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE Chemical Properties,Usage,Production

Uses

6β-Hydroxycortisone-d7 is the isotope labelled analog of 6β-Hydroxycortisone (H918450); a compound that can be used as a probe to detect inhibition of CYP3A4 in vivo.

Definition

ChEBI: 6beta-hydroxycortisone is a C21-steroid that is cortisone bearing an additional hydroxy substituent at the 6beta-position. It is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a probe and a human metabolite. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11-oxo steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisone.

4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE Suppliers

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16355-28-5, 4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONERelated Search:

CORTISONE 4-METHYL-4-HEPTEN-3-OL 11-DEHYDROCORTICOSTERONE CORTEXOLONE 4-Methyl-3-decen-5-ol Progesterone 4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE 2-Allylcyclohexanone (R)-(-)-1-OCTEN-3-OL, 99 1-DECALONE 21-DEOXYCORTISONE Menthone Desoxycorticosterone 4-hydroxy-2-nonenal CYCLOTRIDECANONE undec-1-en-3-ol 4-HHE 11-KETOPROGESTERONE

4-PREGNEN-6-BETA, 17,21-TRIOL-3,11,20-TRIONE

4-PREGNEN-6BETA,17ALPHA,21-TRIOL-3,11,20-TRIONE

4-PREGNENE-6-BETA,17-ALPHA,21-TRIOL-3,11,20-TRIONE

6-BETA,17-ALPHA,21-TRIHYDROXY-4-PREGNENE-3,11,20-TRIONE

6-BETA-HYDROXYCORTISONE

NSC15457

4-Pregnene-6β,17α,21-triol-3,11,20-trione

6β-Hydroxycortisone

6β,17,21-Trihydroxypregna-4-ene-3,11,20-trione

6β,17α,21-Trihydroxypregn-4-ene-3,11,20-trione

(6R,8S,9S,10R,13S,14S,17R)-6,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione

6B-hydroxycortisone approx. 99%

(6R,8S,9S,10R,13S,14S,17R)-6,17-Dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11(2H,6H)-dione

6-BETA-HYDROCORTISONE

4-PREGNEN-6-β, 17,21-TRIOL-3,11,20-TRIONE

Pregn-4-ene-3,11,20-trione, 6,17,21-trihydroxy-, (6β)-

6β-Hydroxycortisone

4-PREGNEN-6β, 17, 21-TRIOL-3, 11, 20-TRIONE

16355-28-5

C21H28O6