Uses
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ISOBUTYLAMINE HYDROCHLORIDE

Uses
Product Name
ISOBUTYLAMINE HYDROCHLORIDE
CAS No.
5041-09-8
Chemical Name
ISOBUTYLAMINE HYDROCHLORIDE
Synonyms
i-BACl;isobutylamineHCl;ISOBUTYLAMMONIUM CHLORIDE;ISOBUTYLAMINE HYDROCHLORIDE;IsobutylamineHydrochloride>2-methylpropylazanium chloride;2-Methylpropan-1-amine hydrochloride;2-Methyl-1-propanamine hydrochloride;1-AMINO-2-METHYLPROPANE HYDROCHLORIDE;1-Propanamine,2-methyl-, hydrochloride (9CI)
CBNumber
CB2687278
Molecular Formula
C4H12ClN
Formula Weight
109.6
MOL File
5041-09-8.mol
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ISOBUTYLAMINE HYDROCHLORIDE Property

Melting point:
176.0 to 180.0 °C
storage temp. 
Inert atmosphere,Room Temperature
Water Solubility 
almost transparency in Water
form 
powder to crystal
color 
White to Almost white
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
26-36/37/39-39
HS Code 
2921199990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
I0096
Product name
Isobutylamine Hydrochloride
Purity
>99.0%(T)
Packaging
25g
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
I0096
Product name
Isobutylamine Hydrochloride
Purity
>99.0%(T)
Packaging
500g
Price
$386
Updated
2025/07/31
TRC
Product number
M322118
Product name
2-Methylpropan-1-amineHydrochloride
Packaging
250mg
Price
$45
Updated
2021/12/16
TRC
Product number
M322118
Product name
2-Methylpropan-1-amineHydrochloride
Packaging
2.5g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
8085AL
Product name
Isobutylamine Hydrochloride
Packaging
25g
Price
$110
Updated
2021/12/16
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ISOBUTYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Isobutylamine hydrochloride is an organic amine hydrochloride, and it has been reported in the literature that it can be used to prepare methyl 3-(2-amino-2-thioethyl)benzoate. Methyl 3-(2-amino-2-thioethyl)benzoate is an important fine chemical raw material and pharmaceutical intermediate. It is a key intermediate for the preparation of a novel phosphate transport inhibitor, 2-[[3-[[4-(2-hydroxyethyl)-2-thiazolyl]methyl]benzoyl]amino]-5-(1-piperidinyl)-,(2E)-2-[[4-chloro-3-(trifluoromethyl)phenyl]methylene]benzoylhydrazine.

Synthesis

72-18-4

5041-09-8

The general procedure for the synthesis of isobutylamine hydrochloride from L-valine is as follows: a magnetic stirring bar, 3 mL of n-propanol (n-PrOH), 10 mmol of R-carvone and 5 mmol of L-valine were added to a pressure vessel. The vessel was heated from room temperature to 190 °C in 5 min under stirring conditions. If the reaction mixture was slurry-like, it was continued at 190°C until the solution became clear. After the vessel was cooled below the boiling point of the solvent, it was carefully vented to release the generated CO2. Subsequently, 10 mL of 2M hydrochloric acid (HCl) was added to the vessel and the vessel was again heated to 190 °C in 5 min under stirring and then cooled. The aqueous reaction mixture was washed three times with 25 mL of ether and the aqueous solvent was removed by distillation to give the hydrochloride product. The hydrochloride was transferred to a vacuum oven and dried overnight at 150 °C and 10 Torr pressure. Finally, the hydrochloride product was weighed and analyzed by infrared spectroscopy (IR) and nuclear magnetic resonance (NMR).The NMR data of 2-methylpropan-1-amine hydrochloride were as follows: δH 0.83 (6H, d, J = 4 Hz), 1.79 (1H, m, J = 8 Hz), 2.69 (2H, d, J = 8 Hz); δC 18.8, 26.2, 46.3.

References

[1] Patent: US2014/275569, 2014, A1. Location in patent: Page/Page column 0045; 0048; 0066; 0067

ISOBUTYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ISOBUTYLAMINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
ISOBUTYLAMINE HYDROCHLORIDE 5041-09-8
Price
US $80.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
customise
Release date
2018-07-25