Ethyl L-valinate hydrochloride
- Product Name
- Ethyl L-valinate hydrochloride
- CAS No.
- 17609-47-1
- Chemical Name
- Ethyl L-valinate hydrochloride
- Synonyms
- H-VAL-OET HCL;ine ethyL;H-VAL-OET·HCL;L-Val-OEt.HCL;VALINE-OET HCL;H-L-Val-OEt*HCl;Exemestane Impurity 48;H-VAL-OET HYDROCHLORIDE;L-VALINE ETHYL ESTER HCL;L-valinate hydrochloride
- CBNumber
- CB0362847
- Molecular Formula
- C7H16ClNO2
- Formula Weight
- 181.66
- MOL File
- 17609-47-1.mol
Ethyl L-valinate hydrochloride Property
- Melting point:
- 102-105 °C(lit.)
- alpha
- 7 º (c=2, H2O)
- storage temp.
- Sealed in dry,Room Temperature
- Water Solubility
- Soluble in water
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- powder to crystal
- color
- White to Almost white
- optical activity
- [α]20/D +6.7°, c = 2 in H2O
- InChI
- InChI=1/C7H15NO2.ClH/c1-4-10-7(9)6(8)5(2)3;/h5-6H,4,8H2,1-3H3;1H/t6-;/s3
- InChIKey
- PQGVTLQEKCJXKF-RGMNGODLSA-N
- SMILES
- [C@H](N)(C(C)C)C(=O)OCC.Cl |&1:0,r|
- CAS DataBase Reference
- 17609-47-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H336May cause drowsiness or dizziness
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 220698
- Product name
- L-Valine ethyl ester hydrochloride
- Purity
- 99%
- Packaging
- 5g
- Price
- $73.1
- Updated
- 2025/07/31
- Product number
- V0142
- Product name
- L-Valine Ethyl Ester Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $20
- Updated
- 2025/07/31
- Product number
- V0142
- Product name
- L-Valine Ethyl Ester Hydrochloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $52
- Updated
- 2025/07/31
- Product number
- V943130
- Product name
- L-Valine Ethyl Ester Hydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 239478
- Product name
- L-Valine ethyl ester hydrochloride 99+%
- Packaging
- 5g
- Price
- $156
- Updated
- 2021/12/16
Ethyl L-valinate hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white crystalline powder
Uses
peptide synthesis
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
64-17-5
72-18-4
17609-47-1
The general procedure for the synthesis of L-valine ethyl ester hydrochloride from ethanol and L-valine is as follows: 5 kg (42.7 mol) of L-valine and 4 kg of anhydrous ethanol were added to a 50-liter glass reactor and stirred until complete dissolution. After cooling the reaction mixture to 0-10°C, 8.8 liters of thionyl chloride were added slowly and dropwise. After the dropwise addition was completed, the reaction mixture was gradually heated to reflux and the reaction was maintained for 18 hours. Upon completion of the reaction, the reaction solution was concentrated to dryness. Subsequently, 15 liters of isopropyl acetate was added to the dried residue at 15 to 20°C and stirred for 1 hour. Finally, the product was collected by diafiltration to give 6.1 kg of off-white solid, Intermediate 1 (where R1 is ethyl).
References
[1] Tetrahedron, 2005, vol. 61, # 35, p. 8423 - 8442
[2] Journal of the Indian Chemical Society, 2001, vol. 78, # 3, p. 137 - 141
[3] Journal of the American Chemical Society, 2018, vol. 140, # 22, p. 6818 - 6822
[4] Chemistry of Natural Compounds, 1994, vol. 30, # 2, p. 238 - 244
[5] Khimiya Prirodnykh Soedinenii, 1994, # 2, p. 261 - 268
Ethyl L-valinate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Ethyl L-valinate hydrochloride Suppliers
- Tel
- 15161820588; 15161820588
- xdchemical2024@163.com
- Country
- China
- ProdList
- 91
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 400-021-7337 2355568890
- Fax
- 0086-21-50182339
- sales@demochem.com
- Country
- China
- ProdList
- 2572
- Advantage
- 57
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
View Lastest Price from Ethyl L-valinate hydrochloride manufacturers
- Product
- Ethyl L-valinate hydrochloride 17609-47-1
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500kgs
- Release date
- 2021-09-29
- Product
- Ethyl L-valinate hydrochloride 17609-47-1
- Price
- US $3.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10000
- Release date
- 2024-09-13
- Product
- Ethyl L-valinate hydrochloride 17609-47-1
- Price
- US $9.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2024-12-05