ChemicalBook > CAS DataBase List > 2-P-ANISYL-1,3-INDANDIONE

2-P-ANISYL-1,3-INDANDIONE

Product Name
2-P-ANISYL-1,3-INDANDIONE
CAS No.
117-37-3
Chemical Name
2-P-ANISYL-1,3-INDANDIONE
Synonyms
andion;Miradon;spe2792;Unidone;SPE 2792;unidione;HSDB 3205;Andindione;Anisindone;nisindione
CBNumber
CB2689681
Molecular Formula
C16H12O3
Formula Weight
252.26
MOL File
117-37-3.mol
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2-P-ANISYL-1,3-INDANDIONE Property

Melting point:
156-157°
Boiling point:
355.44°C (rough estimate)
Density 
1.1824 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly)
form 
Solid
pka
pKa 4.13(H2O t=25.0±0.1 I=0.1(NaCl)) (Uncertain)
color 
White to Off-White
EPA Substance Registry System
Anisindione (117-37-3)
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Safety

RIDADR 
2811
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
117-37-3(Hazardous Substances Data)
Toxicity
mouse,LD50,intraperitoneal,200mg/kg (200mg/kg),Journal of Medicinal Chemistry. Vol. 28, Pg. 1591, 1985.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P308+P313IF exposed or concerned: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A673480
Product name
Anisindione
Packaging
1g
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA29786
Product name
Anisindione
Packaging
1g
Price
$70
Updated
2021/12/16
Matrix Scientific
Product number
063576
Product name
2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione
Packaging
500mg
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA29786
Product name
Anisindione
Packaging
2g
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA29786
Product name
Anisindione
Packaging
5G
Price
$200
Updated
2021/12/16
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2-P-ANISYL-1,3-INDANDIONE Chemical Properties,Usage,Production

Chemical Properties

Slightly beige or yellow powder

Originator

Miradon,Schering,US,1960

Uses

radiopaque agent

Uses

Anisindione is a synthetic anticoagulant that prevents the formation of active procoagulation factors and proteins in the liver.

Definition

ChEBI: A cyclic beta-diketone consisting of indane-1,3-dione having a 4-methoxyphenyl substituent at the 4-position.

Manufacturing Process

To a hot solution of 20.6 g of sodium in 400 ml of absolute ethanol, there is added a solution of 110 g of phthalide and 110 g of p-methoxybenzaldehyde. A vigorous reaction ensues and one-half of the alcohol is distilled off over a two hour period. Ice and water are added to the red solution and the diluted solution is acidified with hydrochloric acid. The resulting gum solidifies and the aqueous phase is removed by decantation. The crude solid is recrystallized twice from two liters of ethanol yielding 2-(p-methoxyphenyl)-1,3-indandione as pale yellow crystals, MP 155-156°C.

brand name

Miradon (Schering).

Therapeutic Function

Anticoagulant

General Description

Anisindione, 2-(p-methoxyphenyl)-1,3-indandione, 2-(p-anisyl)-1,3-indandione (Miradon), is ap-methoxy congener of phenindione. It is a white, crystallinepowder, slightly soluble in water, tasteless, and absorbedwell after oral administration.
In instances when the urine may be alkaline, an orangecolor may be detected. This is caused by metabolic productsof anisindione and is not hematuria.

Purification Methods

Crystallise anisidinone from acetic acid or EtOH. [Horeau & Jacqius Bull Soc Chim Fr 53 1948, Koelsch J Am Chem. Soc 58 1331 1936, Beilstein 8 III 2931.]

2-P-ANISYL-1,3-INDANDIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-P-ANISYL-1,3-INDANDIONE Suppliers

Wuhan Yuanxing Biomedical Technology Co.,
Tel
13642377995
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258676831@qq.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
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Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
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32321
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Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
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(86) 21-58955996
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info@chemexpress.com
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China
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MedChemexpress LLC
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021-58955995
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609-228-5909
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sales@medchemexpress.cn
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United States
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4861
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Shanghai TaoSu Biochemical Technology Co., Ltd.
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021-33632979
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021-34692979
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info@tsbiochem.com
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China
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Target molecule Corp.
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857-239-0968
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857-239-8801
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service1@targetmol.com
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United States
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Tianjin Kailiqi Biotechnology Co., Ltd.
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15076683720
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022-23754520
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klq@cw-bio.com
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China
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4553
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55
Beijing Solarbio Science & Tecnology Co., Ltd.
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010-50973130 4009686088
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3193328036@qq.com
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China
ProdList
29785
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68
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View Lastest Price from 2-P-ANISYL-1,3-INDANDIONE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-P-ANISYL-1,3-INDANDIONE 117-37-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-13

117-37-3, 2-P-ANISYL-1,3-INDANDIONERelated Search:


  • ANISINDIONE
  • 2-P-ANISYL-1,3-INDANDIONE
  • 1,3-Indandione, 2-(p-methoxyphenyl)-
  • 1H-Indene-1,3(2H)-dione, 2-(4-methoxyphenyl)-
  • 2-(4-Methoxyphenyl)-1H-indene-1,3(2H)-dione
  • 2-(4-methoxyphenyl)indan-1,3-dione
  • 2-(p-Methoxyphenyl)-1,3-indandione
  • 2-(p-methoxyphenyl)-3-indandione
  • 2-(p-Methoxyphenyl)indane-1,3-dione
  • 2-para-anisyl-1,3-indandione
  • andion
  • Anisin indandione
  • anisinindandione
  • Miradon
  • SPE 2792
  • spe2792
  • unidione
  • Unidone
  • Andindione
  • Anisindone
  • 2-(4-methoxyphenyl)indane-1,3-quinone
  • 2-(4-methoxyphenyl)indene-1,3-dione
  • 1,3-Indanedione, 2-(4-methoxyphenyl)-
  • 2-(4-methoxyphenyl)indane-1,3-dione
  • Anisindione≥ 98% (TLC)
  • 2-(4-methoxyphenyl)-1h-indene-3(2h)-dione
  • 2-(4-methoxyphenyl)-3-indanedione
  • HSDB 3205
  • nisindione
  • Anisindione,inhibit,Inhibitor
  • 117-37-3
  • Inhibitors
  • OPTIRAY