Jujuboside A

Uses

Product Name: Jujuboside A
CAS No.: 55466-04-1
Chemical Name: Jujuboside A
Synonyms: JUJUBOSIDE A;Jujuboside C;Jujuboside A-RM;Jujuboside A (15 mg);Jujuboside A USP/EP/BP;Jujuboside A 55466-04-1;Pardoprunox Impurity 32;Zizyphus spinosa extract;JUJUBOSIDE A, 98.0% BY HPLC;Ziziphus jujuba Mill. Var
CBNumber: CB2694700
Molecular Formula: C58H94O26
Formula Weight: 1207.35
MOL File: 55466-04-1.mol

More

Less

Jujuboside A Property

Melting point:: 222-225°C
Density: 1.50
storage temp.: 2-8°C
solubility: H2O : 50 mg/mL (41.41 mM; Need ultrasonic)
form: powder
pka: 12.81±0.70(Predicted)
color: White-beige
biological source: plant (Semen Ziziphus spinosa)
Major Application: metabolomics
vitamins, nutraceuticals, and natural products
InChIKey: KVKRFLVYJLIZFD-OWQSYLKINA-N
LogP: -0.194 (est)

More

Less

Safety

Safety Statements: 24/25
WGK Germany: WGK 3
HS Code: 29389090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89719
Product name: Jujuboside A
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $563
Updated: 2026/04/30

Sigma-Aldrich

Product number: SMB00434
Product name: Jujuboside A
Purity: ≥97% (HPLC)
Packaging: 5MG
Price: $264
Updated: 2025/07/31

Sigma-Aldrich

Product number: SMB00434
Product name: Jujuboside A
Purity: ≥97% (HPLC)
Packaging: 25MG
Price: $729
Updated: 2023/06/20

Usbiological

Product number: 297265
Product name: Jujuboside A
Packaging: 50mg
Price: $805
Updated: 2021/12/16

Usbiological

Product number: 300516
Product name: Jujuboside A
Packaging: 20mg
Price: $349
Updated: 2021/12/16

More

Less

Jujuboside A Chemical Properties,Usage,Production

Uses

Jujuboside A is a neuroprotective agent from semen Ziziphi Spinosae, and is used as a hypnotic-sedative compounds.

Chemical Properties

White crystalline powder, easily soluble in methanol, almost insoluble in ether, derived from sour jujube seeds.

Uses

Jujuboside A is a neuroprotective agent from semen Ziziphi Spinosae, and is used as a hypnotic-sedative compounds.

Definition

ChEBI: Jujuboside A is a triterpenoid.

General Description

Jujuboside A (JuA) is a saponin isolated from Semen Ziziphus spinosa (SZS) used in Traditional Chinese Medicine.

Biochem/physiol Actions

Jujuboside A has been shown to be a major hypnotic-sedative and is used for treating insomnia and anxiety.

Synthesis

Preparation of high-purity Jujuboside A reference standard: A. Ethanol extraction of sour jujube seed. B. Enrichment on macroporous resin (water and low-conc. ethanol remove impurities, 50-65% ethanol elutes the target). C. n-Butanol extraction. D. Medium-pressure prep chromatography (50% acetonitrile loading, 30% acetonitrile elution). E. Gel column purification (50% methanol elution). F. Further purification by high-pressure prep chromatography (58% methanol elution). G. Concentration and freeze-drying.

in vivo

During daytime (9:00-15:00), jujubosides significantly increases the total sleep and rapid eye movement (REM) sleep without significant influence on non-REM (NREM) sleep. During nighttime (21:00-3:00), jujubosides significantly increases the total sleep and NREM sleep especially the light sleep while shows no significant effect on REM sleep and slow wave sleep (SWS)^[3]. Intracerebroventricular treatment with Jujuboside A significantly mitigates learning and memory impairment in mice induced by Aβ1–42 as measured by the Y-maze, active avoidance and Morris water maze. Intracerebroventricular treatment with Jujuboside A reduces the level of Aβ1–42 in hippocampus, significantly inhibits the activities of acetylcholinesterase (AChE) and NO, and decreases the amount of the increased malondialdehyde (MDA) in the hippocampus and cerebral cortex of mice treated with intracerebroventricular injection of Aβ1–42^[4].

Jujuboside A Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Jujuboside A Suppliers

China 264 Germany 2 India 1 United Kingdom 8 United States 31 USA 1 Global 307

Hubei CuiRan Biotechnology Co., Ltd.

Tel: 18162795156 18162795156
Email: 3391961471@qq.com
Country: China
ProdList: 4987
Advantage: 58

Shanghai Pureone Bio Technology, CO. LTD

Tel: 18302135232 18302135232
Email: pureonebio@163.com
Country: China
ProdList: 2974
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 18080489829@163.com
Country: China
ProdList: 7973
Advantage: 60

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
ProdList: 297
Advantage: 62

More

Less

View Lastest Price from Jujuboside A manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.

Product: Zizyphus spinosa extract 55466-04-1
Price: US $1200.00-1100.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 1000T/M
Release date: 2025-09-23

Shanghai Standard Technology Co., Ltd.

Product: Jujuboside A 55466-04-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-16

Shanghai Standard Technology Co., Ltd.

Product: Jujuboside A 55466-04-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: Analytical Standard
Supply Ability: 10 g
Release date: 2019-10-16

55466-04-1, Jujuboside ARelated Search:

L(+)-Rhamnose monohydrate D-(-)-Salicin KUROMANIN CHLORIDE ISORHAMNETIN-3-RUTINOSIDE ASTRAGALOSIDE I Hypericin Vitexin (3beta,16beta,23R)-16,23:16,30-Diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-alpha-D-galactopyranosyl-(1-2)-O-[O-beta-D-xylopyranosyl-(1-2)-beta-D-glucopyranosyl-(1-3)]-alpha-L-arabinopyranoside JUJUBOSIDE, A+B ≥2% BY UV FROM JUJUBA PLANT EXTRACT,JUJUBOSIDE B, 98.0% BY HPLC,JUJUBOSIDE B JUJUBOSIDE D 2-ISOBUTYL-4-HYDROXY-4-METHYLTETRAHYDROPYRAN 1,1'-(Ethylidenebis(oxy))bis(3-methylbutane) ISONOMETAL 3993 P Gemcadiol JUJUBOSIDE A(P) Jujuboside A JUJUBOSIDE B(P)

JUJUBOSIDE A

Jujuboside A 55466-04-1

-diepoxy-20-hydroxydammar-24-en-3-ylO-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-

glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-

α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30

(16S,20S,23R)-16,23:16,30-Diepoxy-3β-[2-O-(6-deoxy-α-L-mannopyranosyl)-3-O-[6-O-(β-D-glucopyranosyl)-2-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]-α-L-arabinopyranosyloxy]-5α-dammar-24-en-20-ol

Ziziphus jujuba Mill. Var

O-6-Deoxy-a-L-mannopyranosyl-(1(r)2)-O-[O-b-D-glucopyranosyl-(1(r)6)-O-[b-D-xylopyranosyl-(1(r)2)]-b-D-glucopyranosyl-(1(r)3)]-(3b,16b,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl-a-L-arabinopyranoside

JUJUBOSIDE A, 98.0% BY HPLC

JUJUBOSIDE A, ≥1% BY HPLC JUJUBA PLANT EXTRACT

2)]-b-D-glucopyranosyl-(1&reg

2)-O-[O-b-D-glucopyranosyl-(1&reg

6)-O-[b-D-xylopyranosyl-(1&reg

a-L-Arabinopyranoside, (3b,16b,23R)-16,23:16,30-diepoxy-20-hydroxydaMMar-24-en-3-ylO-6-deoxy-a-L-Mannopyranosyl-(1&reg

Jujuboside A, 98%, from Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chow

α-L-Arabinopyranoside, (3β,16β,23R)-16,23:16,30-diepoxy-20-hydroxydammar-24-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-β-D-glucopyranosyl-(1→6)-O-[β-D-xylopyranosyl-(1→2)]-β-D-glucopyranosyl-(1→3)]-

Jujuboside A USP/EP/BP

Jujuboside C

Jujuboside A (15 mg)

(2S,3R,4R,5R,6S)-2-(((2S,3R,4S,5S)-4-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(((1S,3R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-1-hydroxy-1,6b,9,9,12a-pentamethyl-3-(2-methylprop-1-en-1-yl)hexadecahydro-1H,6H-4a,6a-methanonaphtho[1,2-h]pyrano[2,3-c]isochromen-10-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methylte

Jujuboside A-RM

Pardoprunox Impurity 32

(2S,3R,4R,5R,6S)-2-(((2S,3R,4S,5S)-4-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(((1S,3R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-1-hydroxy-1,6b,9,9,12a-pentamethyl-3-(2-methylprop-1-en-1-yl)hexadecahydro-1H,6H-4a,6a-methanonaphtho[1,2-h]pyrano[2,3-c]isochromen-10-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol

Zizyphus spinosa extract

55466-04-1

C58H94O26

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Miscellaneous Natural Products

The group of Jujubosides