ChemicalBook > CAS DataBase List > 1-BENZOFURAN-5-AMINE

1-BENZOFURAN-5-AMINE

Product Name: 1-BENZOFURAN-5-AMINE
CAS No.: 58546-89-7
Chemical Name: 1-BENZOFURAN-5-AMINE
Synonyms: Benzofuran-5-aMine;5-BenzofuranaMine;5-amino Benzofuran;1-BENZOFURAN-5-AMINE;5-Aminobenzo[b]furan;5-Amino-1-benzofuran;Vilazodone Impurity 11;5-Aminobenzo[b]furan97%;5-Aminobenzo[b]furan 97%;5-Amino-1-benzofuran 97%
CBNumber: CB2697312
Molecular Formula: C8H7NO
Formula Weight: 133.15
MOL File: 58546-89-7.mol

Less

1-BENZOFURAN-5-AMINE Property

Boiling point:: 259.8±13.0 °C(Predicted)
Density: 1.225±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.87±0.10(Predicted)
form: liquid
color: Orange
InChI: InChI=1S/C8H7NO/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5H,9H2
InChIKey: GMOLCSICTCPZCU-UHFFFAOYSA-N
SMILES: O1C2=CC=C(N)C=C2C=C1

Less

Safety

Hazard Note: Harmful
HS Code: 2932990090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

TRC

Product number: B203625
Product name: 5-Benzofuranamine
Packaging: 100mg
Price: $345
Updated: 2021/12/16

Apolloscientific

Product number: OR9276
Product name: 5-Aminobenzo[b]furan
Purity: 97%
Packaging: 250mg
Price: $76
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H30-1-V3
Product name: 5-Aminobenzo[b]furan
Purity: 97%
Packaging: 250mg
Price: $84
Updated: 2021/12/16

Apolloscientific

Product number: OR9276
Product name: 5-Aminobenzo[b]furan
Purity: 97%
Packaging: 1g
Price: $177
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H30-1-V3
Product name: 5-Aminobenzo[b]furan
Purity: 97%
Packaging: 1g
Price: $196
Updated: 2021/12/16

Less

1-BENZOFURAN-5-AMINE Chemical Properties,Usage,Production

Uses

5-Benzofuranamine acts as a reagent in the synthesis of substituted pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents.

Definition

ChEBI: 1-Benzofuran-5-amine is a member of benzofurans.

Synthesis

18761-31-4

7439-89-6

58546-89-7

Step 1. 5-Nitrobenzofuran (Compound 104, 1.89 g, 11.63 mmol), iron powder (6.5 g, 116 mmol), 36.5% hydrochloric acid (1 mL), ethanol (30 mL), and water (6 mL) were mixed, stirred, and heated to 100 °C, and the reaction was maintained for 3 hours. After completion of the reaction, the precipitate was filtered and washed with ethanol. The filtrates were combined and the solvent was removed by evaporation to give a residue. The residue was dissolved in dichloromethane (50 mL) and the organic layer was washed sequentially with aqueous sodium bicarbonate (20 mL x 2) and brine (20 mL x 1), dried over magnesium sulfate, filtered and the solvent was evaporated to afford 1-benzofuran-5-amine (Compound 105) as a brown solid (0.8 g, 51% yield).LC-MS: 134 [M + 1]+; 1H NMR ( DMSO-d6): δ 4.8 (s, 2H), 6.57 (m, 1H), 6.67 (m, 1H), 6.69 (m, 1H), 7.21 (d, J = 9.3 Hz, 1H), 7.74 (d, J = 2.4 Hz, 1H).

References

[1] Patent: US2009/76044, 2009, A1. Location in patent: Page/Page column 25

1-BENZOFURAN-5-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

1-BENZOFURAN-5-AMINE Suppliers

Belgium 1 China 63 India 4 United Kingdom 2 United States 12 Global 82

Block Chemical Technology (Shanghai) Co., Ltd.

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 10034
Advantage: 58

Shanghai Sainty Biotechnology Co., Ltd.

Tel: 021-58957915 17721108391
Fax: QQ: 907522080
Email: 907522080@qq.com
Country: China
ProdList: 997
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Hefei Shenghang Pharmaceutical Technology Co., Ltd.

Tel: 18326946292
Email: 2816071490@QQ.COM
Country: China
ProdList: 58
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Nanjing JinruiJiuAn Biotechnology Co., Ltd.

Tel: 025-58196018 800028039
Fax: 025-83453306
Email: sales@fartop.net
Country: China
ProdList: 2229
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 0086-15250997978
Fax: 025-58362220
Email: sale@njxizebio.com
Country: China
ProdList: 4855
Advantage: 55

Beatrice medicine technology Co., Ltd.

Tel: 15769589321 1548536191
Email: beatricechem@aliyun.com
Country: China
ProdList: 460
Advantage: 50

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-0755-28967200-8062 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9624
Advantage: 60

Biokitchen

Tel: 021-021-021-31663258 13795219287
Fax: 021-31663258
Email: donghuanwen@126.com
Country: China
ProdList: 8816
Advantage: 58

Combiphos (Shanghai) Biological Technology Co., Ltd.

Tel: 021-65232103 17602124823
Email: combiphos@vip.qq.com
Country: China
ProdList: 30000
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Yujinpharma(Tianjin) Technology Co.,Ltd.

Tel: 13370351217 kungfu1217@1
Fax: QQ1400885609
Email: kungfu1217@163.com
Country: China
ProdList: 2720
Advantage: 58

Shanghai Benso Pharmaceutical Technology Co., Ltd.

Tel: 15088289376
Email: 248775804@qq.com
Country: China
ProdList: 4995
Advantage: 58

Shanghai Hongle Biotechnology Co., Ltd

Tel: 021-56145923; 4001631568
Email: sales@honglebiotech.com
Country: China
ProdList: 920
Advantage: 58

Shanghai Gugang New Materials Technology Co. Ltd.

Tel: 021-51317962
Fax: 021-51317962
Email: 296935822@qq.com
Country: China
ProdList: 986
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 10467
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Henan Weitesi Chemical Technology Co. LTD

Tel: 0371-0371-55135753 18003832934
Fax: QQ：2853979818
Email: 2853979818@qq.com
Country: China
ProdList: 9991
Advantage: 58

Shanghai Sunmonth Technology Co., LTD

Tel: 15216675652
Email: xuanyuelj@163.com
Country: China
ProdList: 2864
Advantage: 58

Shanghai Hecheng Medical Technology Co., LTD

Tel: 13564747822
Fax: QQ774046800
Email: 669027880@qq.com
Country: China
ProdList: 946
Advantage: 58

Block Chemical Technology (Shanghai) Co., Ltd.

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 11318
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Beijing Stronger Science Co., Ltd.

Tel: 0531-88924771 15614660963
Email: elsa.hang@strongerscience.com
Country: China
ProdList: 10623
Advantage: 58

Henan yingchuang

Tel: 16650708709
Fax: qq:778660296
Email: hnyingchuang@163.com
Country: China
ProdList: 3966
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815987 13927875076
Fax: 0751-2828607
Email: 3007432263@qq.com
Country: China
ProdList: 9963
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Beijing InnoChem Science & Technology Co., Ltd.

Tel: 15652467323
Email: sales@inno-chem.com.cn
Country: China
ProdList: 8293
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Qunsheng Pharmaceutical Technology L,td

Tel: 15316975816
Email: azachem@qq.com
Country: China
ProdList: 946
Advantage: 58

Xi'an Ruicheng Pharmaceutical Technology Co., Ltd

Tel: 17791728244
Email: 3356623179@qq.com
Country: China
ProdList: 879
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188 13327728092
Email: sales@pharmablock.com
Country: China
ProdList: 10000
Advantage: 58

58546-89-7, 1-BENZOFURAN-5-AMINERelated Search:

5-Amino-1-benzofuran

5-Amino-1-benzofuran 97%

5-Aminobenzo[b]furan

1-BENZOFURAN-5-AMINE

5-Aminobenzo[b]furan 97%

1-Benzofuran-5-amine, Benzo[b]furan-5-amine

Vilazodone Impurity 11

5-amino Benzofuran

5-BenzofuranaMine

Benzofuran-5-aMine

5-Aminobenzo[b]furan97%

Vilazodone Impurity 11 (5-Amino Benzofuran)

Vilazidone amino benzofuron

58546-89-7