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METHOXYRESORUFIN

Product Name
METHOXYRESORUFIN
CAS No.
5725-89-3
Chemical Name
METHOXYRESORUFIN
Synonyms
METHOXYRESORUFIN;O-Methylresorufin;7-methoxyresorufin;O7-Methylresorufin;O7-METHYLRESORUFINE;7-Methoxyphenoxazone;Fluazifop Impurity 5;RESORUFIN METHYL ETHER;7-methoxyphenoxazin-3-one;RESORUFIN 7-O-METHYL ETHER
CBNumber
CB2723594
Molecular Formula
C13H9NO3
Formula Weight
227.22
MOL File
5725-89-3.mol
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METHOXYRESORUFIN Property

Melting point:
≥220 °C(lit.)
Boiling point:
378.8±42.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: soluble
pka
1.42±0.20(Predicted)
form 
Powder
color 
Brown to reddish brown
BRN 
209529
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
3-8-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M1544
Product name
Resorufin methyl ether
Packaging
1mg
Price
$213
Updated
2024/03/01
Sigma-Aldrich
Product number
69125
Product name
Resorufin methyl ether
Purity
suitable for fluorescence, ≥98.0% (HPLC)
Packaging
5mg
Price
$222
Updated
2022/05/15
Cayman Chemical
Product number
14852
Product name
Methoxyresorufin
Packaging
1mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
14852
Product name
Methoxyresorufin
Packaging
5mg
Price
$239
Updated
2024/03/01
Sigma-Aldrich
Product number
M1544
Product name
Resorufin methyl ether
Packaging
5mg
Price
$793
Updated
2024/03/01
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METHOXYRESORUFIN Chemical Properties,Usage,Production

Description

Methoxyresorufin is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. Methyoxyresorufin is O-demethylated by CYP1A1/2, releasing resorufin, which displays excitation/emission maxima of 570/580 nm, respectively. The appearance of resorufin fluorescence can be used to quantify CYP1A1/2 activity.

Uses

Used to differentiate isozymes of cytochrome P-450

Uses

Substrate for Cytochrome P-450. METHOXYRESORUFIN is used for various investigations including the differentiatiation of cytochrome P-450 isozymes.

Uses

Resorufin methyl ether have been used as substrate in the incubation mixture, during the determination of cytochrome P4501A activities such as ethoxyresorufin O-deethylase (EROD) and methoxyresorufin O-demethylase(MROD) in liver microsomes, using high performance liquid chromatography(HPLC).

Biochem/physiol Actions

Fluorimetric substrate for cytochrome P450 linked enzymes.

METHOXYRESORUFIN Preparation Products And Raw materials

Raw materials

Preparation Products

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5725-89-3, METHOXYRESORUFINRelated Search:

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  • O-Methylresorufin
  • 7-methoxyphenoxazin-3-one
  • Resorufin methyl ether,7-Methoxy-3H-phenoxazin-3-one, Methoxyresorufin, O7-Methylresorufin
  • O7-Methylresorufin
  • Resorufin methyl ether *CAS 5725-89-3*
  • Fluazifop Impurity 5
  • Resorufin methyl ether (7-Meth)oxyresorufin), Fluorometric cytochrome P450 substrate
  • 5725-89-3
  • BioChemical
  • Biochemicals and Reagents
  • Fluorescent Enzyme Substrates
  • Fluorescent Probes, Labels, Particles and Stains
  • Alphabetical
  • Detection