ChemicalBook > CAS DataBase List > METHOXYRESORUFIN

METHOXYRESORUFIN

Product Name: METHOXYRESORUFIN
CAS No.: 5725-89-3
Chemical Name: METHOXYRESORUFIN
Synonyms: METHOXYRESORUFIN;O-Methylresorufin;7-methoxyresorufin;O7-Methylresorufin;O7-METHYLRESORUFINE;7-Methoxyphenoxazone;Fluazifop Impurity 5;RESORUFIN METHYL ETHER;Methoxyresorufin - 5 mg;7-methoxyphenoxazin-3-one
CBNumber: CB2723594
Molecular Formula: C13H9NO3
Formula Weight: 227.22
MOL File: 5725-89-3.mol

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METHOXYRESORUFIN Property

Melting point:: ≥220 °C(lit.)
Boiling point:: 378.8±42.0 °C(Predicted)
Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: soluble
pka: 1.42±0.20(Predicted)
form: Powder
color: Brown to reddish brown
Appearance: Solid Powder
BRN: 209529

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 3-8-10

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M1544
Product name: Resorufin methyl ether
Packaging: 1mg
Price: $219
Updated: 2025/07/31

Sigma-Aldrich

Product number: 69125
Product name: Resorufin methyl ether
Purity: suitable for fluorescence, ≥98.0% (HPLC)
Packaging: 5mg
Price: $222
Updated: 2022/05/15

Cayman Chemical

Product number: 14852
Product name: Methoxyresorufin
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 14852
Product name: Methoxyresorufin
Packaging: 5mg
Price: $239
Updated: 2024/03/01

Sigma-Aldrich

Product number: M1544
Product name: Resorufin methyl ether
Packaging: 5mg
Price: $815
Updated: 2025/07/31

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METHOXYRESORUFIN Chemical Properties,Usage,Production

Description

Methoxyresorufin is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. Methyoxyresorufin is O-demethylated by CYP1A1/2, releasing resorufin, which displays excitation/emission maxima of 570/580 nm, respectively. The appearance of resorufin fluorescence can be used to quantify CYP1A1/2 activity.

Uses

Used to differentiate isozymes of cytochrome P-450

Uses

Substrate for Cytochrome P-450. METHOXYRESORUFIN is used for various investigations including the differentiatiation of cytochrome P-450 isozymes.

Uses

Resorufin methyl ether have been used as substrate in the incubation mixture, during the determination of cytochrome P4501A activities such as ethoxyresorufin O-deethylase (EROD) and methoxyresorufin O-demethylase(MROD) in liver microsomes, using high performance liquid chromatography(HPLC).

Biochem/physiol Actions

Fluorimetric substrate for cytochrome P450 linked enzymes.

IC 50

CYP1

References

[1] RICHARD T. MAYER . Methoxyresorufin as a substrate for the fluorometric assay of insect microsomal O-dealkylases[J]. Pesticide Biochemistry and Physiology, 1977, 7 4: Pages 349-354. DOI: 10.1016/0048-3575(77)90038-4
[2] PRATIBHA V. NERURKAR . Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 AND 2B, respectively, in the rat and mouse[J]. Biochemical pharmacology, 1993, 46 5: Pages 933-943. DOI: 10.1016/0006-2952(93)90504-p
[3] M.V. CABALLERO . Fipronil induces CYP isoforms in rats[J]. Food and Chemical Toxicology, 2015, 83: Pages 215-221. DOI: 10.1016/j.fct.2015.06.019
[4] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.

Excitation / Emission Maximum

571 nm/585 nm

METHOXYRESORUFIN Preparation Products And Raw materials

Raw materials

Preparation Products

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5725-89-3, METHOXYRESORUFINRelated Search:

p-Anisidine Guaiacol Hydrazine sulfate RESORUFIN RESORUFIN BENZYL ETHER RESORUFIN ETHYL ETHER METHOXYRESORUFIN 1,2-DI-O-LAURYL-RAC-GLYCERO-3-GLUTARIC ACID 6'-METHYLRESORUFIN ESTER RESORUFIN PENTYL ETHER RESORUFIN ACETATE 3-PHENOXAZONE 7-[BETA-D-GLUCURONIDE] SODIUM SALT RESORUFIN BETA-D-GLUCOPYRANOSIDE RESORUFIN OLEATE RESORUFIN BUTYRATE RESORUFIN BETA-D-GALACTOPYRANOSIDE methoxyresorufin-O-demethylase RESORUFIN BETA-D-GLUCURONIDE, POTASSIUM SALT RESORUFIN BETA-D-N-ACETYLGALACTOSAMINE

7-methoxyresorufin

O7-METHYLRESORUFINE

RESORUFIN 7-O-METHYL ETHER

RESORUFIN METHYL ETHER

7-METHOXY-3H-PHENOXAZIN-3-ONE

METHOXYRESORUFIN

O(7)-METHYLRESORUFINE, FOR FLUOR-ESCENCE

3H-Phenoxazin-3-one, 7-methoxy-

METHOXYRESORUFIN [RESORUFIN METHYL ETHER]

7-Methoxy-3H-phenoxazin-3-one, Methoxyresorufin, O7-Methylresorufin

7-Methoxyphenoxazone

O-Methylresorufin

7-methoxyphenoxazin-3-one

Resorufin methyl ether,7-Methoxy-3H-phenoxazin-3-one, Methoxyresorufin, O7-Methylresorufin

O7-Methylresorufin

Resorufin methyl ether *CAS 5725-89-3*

Fluazifop Impurity 5

Resorufin methyl ether (7-Meth)oxyresorufin), Fluorometric cytochrome P450 substrate

Methoxyresorufin - 5 mg

5725-89-3

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Fluorescent Enzyme Substrates

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