BACE-1

Product Name: BACE-1
CAS No.: 158736-49-3
Chemical Name: BACE-1
Synonyms: ASP-2;BACE-1;HSPC104;MEMAPSIN-2;B-SECRETASE;HUMAN BACE-1;β-Secretase human;HUMAN BETA-SECRETASE;BETA-SECRETASE HUMAN;BETA-SECRETASE ENZYME
CBNumber: CB2730309
Formula Weight: 0
MOL File: Mol file

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BACE-1 Property

storage temp.: 2-8°C
form: buffered aqueous solution
Specific Activity: ≥10,000units/mg protein

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: -

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S4195
Product name: β-Secretase human
Purity: recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), ≥10,000 units/mg protei
Packaging: 50 μg
Price: $371.05
Updated: 2025/07/31

Sigma-Aldrich

Product number: S4195
Product name: β-Secretase human
Purity: recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), extracellular domain, ≥10,000?units/mg protein, ≥90% (SDS-PAGE), buffered aqueous solution
Packaging: 50μG
Price: $373
Updated: 2023/06/20

Sigma-Aldrich

Product number: SAB2900193
Product name: Anti-BACE1 (AB1) antibody produced in rabbit
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 50μg
Price: $599
Updated: 2022/05/15

Usbiological

Product number: 354173
Product name: BACE1
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

Usbiological

Product number: 354172
Product name: BACE1
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

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BACE-1 Chemical Properties,Usage,Production

Uses

Human β-secretase or BACE1 has been used to study the binding reaction between amyloid precursor protein and β-secretase. It has also been used in BACE1 assay.

Biochem/physiol Actions

BACE1 (β-site APP-cleaving enzyme 1) is a transmembrane aspartyl protease responsible for cleaving the amyloid precursor protein (APP). BACE1-mediated cleavage of amyloid precursor protein (APP) is the first step during the generation of pathogenic amyloid-β peptides, hence making it the major drug target for Alzheimer′s disease (AD). Increased levels of enzymatic activity of BACE1 was found in cerebrospinal fluid from patients having both mild cognitive impairment (MCI) and AD, thereby suggesting the importance of BACE1 enzymatic activity in conversion of MCI to AD.

BACE-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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BACE-1 Suppliers

China 28 Switzerland 1 United States 7 Global 36

United States Biological

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Email: sales@advtechind.com
Country: United States
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Creative Enzymes

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Fax: 1-631-938-8127
Email: info@creative-enzymes.com
Country: United States
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Creative Enzymes

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Country: United States
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Riedel-de Haen AG

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MP Biomedicals, Inc.

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R & D Systems

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Country: United States
ProdList: 2195
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Kamiya Biomedical Company

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Country: United States
ProdList: 736
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158736-49-3, BACE-1Related Search:

ZIP kinase Recombinant Human R-Spondin-3/RSPO3 (C-Fc-6His) EMMPRIN glypican 4 Glycoprotein B Recombinant Human CD52 IL5RA NEUROGRANIN LIFR Recombinant Human Ephrin-A3/EFNA3(C-6His)

MEMAPSIN-2

HUMAN BETA-SECRETASE

HUMAN BACE-1

ASP-2

B-SECRETASE

BETA-SECRETASE ENZYME

BETA-SECRETASE HUMAN

BACE-1

Asp-2, BACE1, Memapsin-2

β-Secretase human

Anti-BACE, C-Terminal antibody produced in rabbit

β-secretase precursor

Anti-BACE1 (AB1) antibody produced in rabbit

Human BACE1/APS2 Protein, His Tag

Human BACE1/APS2 Protein, Fc Tag

Beta-site amyloid precursor protein cleaving enzyme 1

HSPC104

Membrane-associated aspartic protease 2

158736-49-3