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BICALUTAMIDE-D4

Product Name
BICALUTAMIDE-D4
CAS No.
1185035-71-5
Chemical Name
BICALUTAMIDE-D4
Synonyms
Casodex-d4;ICI-176334-d4;(CI-176334-D4;BICALUTAMIDE-D4;[2H4]-Bicalutamide;Bicalutamide Impurity 17;N-[4-Cyano-3-trifluoromethyl)phenyl]- 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide-d4
CBNumber
CB2737393
Molecular Formula
C18H14F4N2O4S
Formula Weight
430.37
MOL File
Mol file
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BICALUTAMIDE-D4 Property

Melting point:
192-1940C
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22377
Product name
Bicalutamide-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
500μg
Price
$219
Updated
2024/03/01
Cayman Chemical
Product number
22377
Product name
Bicalutamide-d4
Purity
≥99% deuterated forms (d1-d4)
Packaging
1mg
Price
$414
Updated
2024/03/01
Usbiological
Product number
B1087-55A
Product name
Bicalutamide-d4
Packaging
1mg
Price
$496
Updated
2021/12/16
TRC
Product number
B382002
Product name
Bicalutamide-d4
Packaging
10mg
Price
$1695
Updated
2021/12/16
AK Scientific
Product number
3488DH
Product name
Bicalutamide-d4
Packaging
1mg
Price
$559
Updated
2021/12/16
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BICALUTAMIDE-D4 Chemical Properties,Usage,Production

Description

Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

Chemical Properties

BICALUTAMIDE-D4 is White Solid

Uses

BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0

BICALUTAMIDE-D4 Preparation Products And Raw materials

Raw materials

Preparation Products

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BICALUTAMIDE-D4 Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
TLC PharmaChem Inc.
Tel
--
Fax
--
Email
research@tlcpharmachem.com
Country
Canada
ProdList
921
Advantage
60
SynFine Research, Inc.
Tel
--
Fax
--
Email
research@synfine.com.
Country
Canada
ProdList
768
Advantage
42