4-NITRO-ISATOIC ANHYDRIDE
- Product Name
- 4-NITRO-ISATOIC ANHYDRIDE
- CAS No.
- 63480-10-4
- Chemical Name
- 4-NITRO-ISATOIC ANHYDRIDE
- Synonyms
- NSC 135175;4-NITRO-ISATOIC ANHYDRIDE;4-Nitroisatoicanhydride97%;4-Nitroisatoic anhydride 97%;7-nitro-1H-3,1-benzoxazine-2,4-dion;7-nitro-1H-3,1-benzoxazine-2,4-dione;7-Nitro-2H-3,1-benzoxazine-2,4(1H)-dione;7-NITRO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE;2H-3,1-Benzoxazine-2,4(1H)-dione, 7-nitro-;7-nitro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione
- CBNumber
- CB2744890
- Molecular Formula
- C8H4N2O5
- Formula Weight
- 208.13
- MOL File
- 63480-10-4.mol
4-NITRO-ISATOIC ANHYDRIDE Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- wooly crystalline powder
- color
- Lemon
- CAS DataBase Reference
- 63480-10-4(CAS DataBase Reference)
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N515280
- Product name
- 4-NitroisatoicAnhydride
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 4H54-1-59
- Product name
- 4-Nitroisatoic anhydride
- Packaging
- 5G
- Price
- $96
- Updated
- 2021/12/16
- Product number
- OR400019
- Product name
- 4-Nitroisatoicanhydride
- Purity
- 95%
- Packaging
- 1g
- Price
- $19
- Updated
- 2021/12/16
- Product number
- 4H54-1-59
- Product name
- 4-Nitroisatoic anhydride
- Packaging
- 1g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- W7542
- Product name
- 4-Nitroisatoicanhydride
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
4-NITRO-ISATOIC ANHYDRIDE Chemical Properties,Usage,Production
Synthesis
32315-10-9
619-17-0
63480-10-4
The general procedure for the synthesis of 7-nitro-1H-benzo[d][1,3]oxazine-2,4-dione from tritiated gas and 2-amino-4-nitrobenzoic acid was as follows: to a 500 mL single-necked round-bottomed flask equipped with a soccer ball shaped PTFE stirring bar (16 mm × 37 mm) was added 2-amino-4-nitrobenzoic acid (10.0 g, 46.3 mmol, 1.0 eq. ), followed by tetrahydrofuran (230 mL, 0.2 M) and solid triphosgene (13.7 g, 46.3 mmol, 1.0 eq.) to form a suspension. The reaction flask was placed in a device equipped with a metal heating jacket with a 24/40 Liebig condenser attached to the neck of the flask. The suspension was stirred at 500 rpm and the temperature of the heating jacket was set to 70°C. After about 30 minutes, the suspension became homogeneous and subsequently precipitated a white solid. The non-homogeneous reaction mixture was allowed to stand for 12 hours and then cooled to room temperature (25°C). The reaction slurry was poured into a 600 mL beaker equipped with an overhead mechanical stirrer (PTFE 75 mm paddle) and 250 mL of deionized water was added. Under vigorous stirring, the mixture first became homogeneous and then precipitated as a pale white solid. The solids were collected by vacuum filtration through a Brinell funnel (7.6 cm diameter, lined with Whatman 1 filter paper, 70 mm) and purged with air for 5 min. The resulting solids were transferred to a 250 mL conical flask, 50 mL of methanol was added, and the slurry was stirred using a cylindrical rod for 10 min, after which the solids were again collected by vacuum filtration. The filter cake was dried under vacuum (0.1 mmHg, 25 °C) for 12 h. The final product was 7-nitro-1H-benzo[d][1,3]oxazine-2,4-dione as a white powder in 90% yield.
References
[1] Beilstein Journal of Organic Chemistry, 2018, vol. 14, p. 2529 - 2536
[2] European Journal of Medicinal Chemistry, 1994, vol. 29, # 12, p. 925 - 940
[3] Patent: EP1719771, 2006, A1. Location in patent: Page/Page column 51
[4] Journal of Agricultural and Food Chemistry, 2015, vol. 63, # 31, p. 6883 - 6889
4-NITRO-ISATOIC ANHYDRIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-NITRO-ISATOIC ANHYDRIDE manufacturers
- Product
- 4-NITRO-ISATOIC ANHYDRIDE 63480-10-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-07