ChemicalBook > CAS DataBase List > AVICULARIN

AVICULARIN

Product Name: AVICULARIN
CAS No.: 572-30-5
Chemical Name: AVICULARIN
Synonyms: QUERCETIN-3-ARABINOSIDE;Quercetin 3-α-L-arabinofuranoside;AVICULARIN;Fenicularin;Avicularoside;Avicularin-RM;common Knotgrass Herb;Avicularin (6CI, 7CI, 8CI);3α-Hydroxy-5β-cholanic acid;QUERCETIN-3-ARABINOSIDE hplc
CBNumber: CB2753735
Molecular Formula: C20H18O11
Formula Weight: 434.35
MOL File: 572-30-5.mol

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AVICULARIN Property

Melting point:: 207-208 °C
Boiling point:: 855.4±65.0 °C(Predicted)
Density: 1.86±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly, Sonicated), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form: Solid
pka: 6.17±0.40(Predicted)
color: Pale Yellow to Light Yellow
Stability:: Hygroscopic
InChI: InChI=1/C20H18O11/c21-8-4-11(24)14-13(5-8)30-18(7-1-2-9(22)10(23)3-7)19(16(14)27)31-20-17(28)15(26)12(25)6-29-20/h1-5,12,15,17,20-26,28H,6H2/t12-,15-,17+,20?/s3
InChIKey: PZZRDJXEMZMZFD-TTYPJOBMNA-N
SMILES: C1(OC2=C(C(O)=CC(O)=C2)C(=O)C=1OC1OC[C@H](O)[C@H](O)[C@H]1O)C1C=CC(O)=C(O)C=1 |&1:17,19,21,r|

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 44006
Product name: Avicularin
Purity: analytical standard
Packaging: 5mg
Price: $484
Updated: 2022/05/15

Usbiological

Product number: 299977
Product name: Avicularin
Packaging: 20mg
Price: $575
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 74061
Product name: Avicularin
Purity: 98%
Packaging: 20mg
Price: $567
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0001311
Product name: AVICULARIN
Purity: 98.00%
Packaging: 10MG
Price: $1155
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FQ65464
Product name: Quercetin-3-arabinoside
Packaging: 1mg
Price: $65
Updated: 2021/12/16

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AVICULARIN Chemical Properties,Usage,Production

Chemical Properties

Pale yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from Saururus chinensis (Lour.) Baill.

Uses

Quercetin-3-arabinoside can be used to prevent or treat degenerative brain disease.

Definition

ChEBI: A quercetin O-glycoside in which an alpha-L-arabinofuranosyl residue is attached at position 3 of quercetin via a glycosidic linkage. It is isolated particularly from Juglans regia and ital Foeniculum vulgare.

in vivo

Avicularin (injected in articular cavity of the knee, 0.5-2 mg/kg, twice a week for 4 weeks) attenuates the development of OA (osteoarthritis) in ACLT-induced rats^[4].
? Avicularin (oral administration, 50 and 100 mg/kg, for 21 days) attenuates memory Impairment in rats with amyloid Beta-induced Alzheimer's disease^[5].

Animal Model:	ACLT (anterior cruciate ligament transection)-induced rats^[4]
Dosage:	0.5, 1, 2 mg/kg
Administration:	Injected into the articular cavity of the right knee, twice a week for 4 weeks.
Result:	Alleviated the tibial subchondral osteolysis, reduces bone loss, and increases the bone mass of tibial subchondral bone. Attenuated ECM degradation, the loss of Aggrecan and Collagen II in ACLT-induced rats. Decreased the MMP3 and MMP13 protein level.

Animal Model:	Rats with amyloid Beta-induced Alzheimer's disease^[5]
Dosage:	25, 50, and 100 mg/kg
Administration:	Oral administration, for 21 days
Result:	Enhanced cognition activity, and reversed the effects of amyloid beta-induced inflammatory response and excessive oxidative stress.

IC 50

GLUT4; PPARγ; COX-2

AVICULARIN Preparation Products And Raw materials

Raw materials

Preparation Products

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AVICULARIN Suppliers

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View Lastest Price from AVICULARIN manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Avicularin 572-30-5
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-16

Shanghai Standard Technology Co., Ltd.

Product: Avicularin 572-30-5
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: avicularin 572-30-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

572-30-5, AVICULARINRelated Search:

Trypsin Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) 4',5-DIHYDROXY-7-METHOXYFLAVONE ISOQUERCITRIN hydroxygenkwanin Quercetin-7-O-β-D-glucopyranoside MOSLOFLAVONE PONCIRIN GARDENIN B 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one FRIEDELAN-3BETA-OL AVICULARIN(SH) 2'-O-GALLOYLHYPERIN Hyperoside SYRINGETIN-3-GALACTOSIDE AVICULARIN MYRICETIN 3-O-L-ARABINOPYRANOSIDE MYRICETIN-3-GALACTOSIDE

AVICULARIN

QUERCETIN-3-ARABINOSIDE

Avicularoside

Fenicularin

3-(α-L-Arabinofuranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one

Quercetin 3-α-L-arabinofuranoside

Avicularin(Quercetin 3-alpha-L-arabinofuranoside)

QUERCETIN-3-ARABINOSIDE hplc

Quercetin 3-O-α-L-arabinofuranoside

3,3′,4′,5,7-Pentahydroxyflavone 3-O-α-L-arabinofuranoside

Avicularin, 98%, from Polygonum aviculare L.

4H-1-Benzopyran-4-one, 3-(α-L-arabinofuranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-

3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one

3α-Hydroxy-5β-cholanic acid

Avicularin (6CI, 7CI, 8CI)

3-(((2S,3R,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one

common Knotgrass Herb

Avicularin-RM

572-30-5

Flavanols

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract