Description References
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Trypsin

Description References
Product Name
Trypsin
CAS No.
9002-07-7
Chemical Name
Trypsin
Synonyms
500mg;TRYPSIN-EDTA;EC 3.4.21.1;TRYPSIN PORCINE;RecoMbinant Trypsin;trypsin from porcine pancreas;Lys-C;C00298;u-4858;Tryprar
CBNumber
CB0673677
Molecular Formula
C35H47N7O10
Formula Weight
725.78858
MOL File
9002-07-7.mol
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Trypsin Property

Melting point:
115°C
Density 
1.37[at 20℃]
vapor pressure 
0Pa at 25℃
storage temp. 
-20°C
solubility 
Reconstitute in aqueous buffer
form 
lyophilized powder
pka
pK1:6.25 (25°C,μ=0.1)
color 
White powder
Odor
Odorless
Water Solubility 
Soluble in water (10 mg/ml), phosphate buffers (10 mg/ml), and balanced salt solutions (1 mg/ml).
Merck 
13,9865
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
-1.3 at 20℃
CAS DataBase Reference
9002-07-7
EPA Substance Registry System
Trypsin (9002-07-7)
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Safety

Hazard Codes 
Xn,B
Risk Statements 
36/37/38-42-42/43
Safety Statements 
22-24-26-36/37-45-23
WGK Germany 
2
RTECS 
GC3050000
1-3-10
TSCA 
Yes
HS Code 
35079090
Hazardous Substances Data
9002-07-7(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P284Wear respiratory protection.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T9201
Product name
Trypsin from bovine pancreas
Purity
powder, ≥7,500?BAEE units/mg solid
Packaging
100MG
Price
$120
Updated
2024/03/01
Sigma-Aldrich
Product number
T9201
Product name
Trypsin from bovine pancreas
Purity
powder, ≥7,500?BAEE units/mg solid
Packaging
500MG
Price
$186
Updated
2024/03/01
Sigma-Aldrich
Product number
T9201
Product name
Trypsin from bovine pancreas
Purity
powder, ≥7,500?BAEE units/mg solid
Packaging
1G
Price
$302
Updated
2024/03/01
Sigma-Aldrich
Product number
T9201
Product name
Trypsin from bovine pancreas
Purity
powder, ≥7,500?BAEE units/mg solid
Packaging
5G
Price
$840
Updated
2024/03/01
Sigma-Aldrich
Product number
T9201
Product name
Trypsin from bovine pancreas
Purity
powder, ≥7,500?BAEE units/mg solid
Packaging
10G
Price
$1340
Updated
2024/03/01
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Trypsin Chemical Properties,Usage,Production

Description

Trypsin is a serine protease in the digestive system of human and animals. The main function of this enzyme is to hydrolyze proteins into smaller peptides or even amino acids. Trypsin and other digestive proteases such as chymotrypsin are responsible for the digestion of food protein in the small intestine. This proteolytic function of trypsin has been widely used in the protein chemistry, proteomics, and nutrition research. This function is influenced by the sources of enzyme, and environmental factors such as pH, temperature, and the presence of trypsin inhibitors in the enzymatic reaction medium.
Trypsin is used in the food processing to improve the functional properties such as solubility, emulsification, foaming and gelling properties of food proteins, to improve the digestibility of vegetable and seed proteins. It is used to reduce the concentration of allergens in some foods and to produce protein hydrolysates and bioactive peptides that are used in infant formulas and for people with special health problems such as hypertension. In food science research, trypsin is used for the food protein sequencing, in-vitro determination of food protein digestibility.  In combination with bromelain and rutin, trypsin is used for osteoarthritis. Trypsin is used to remove necrotic tissue and debris during wound and ulcer cleaning. Trypsin supplements may be used to remove dead tissue cells that remain after trauma, infection or surgical procedures, allowing new skin or tissue cells to grow.

References

[1] http://www.cytospring.com/pages/TrypsinEDTA.pdf
[2] Jianmei Yu, Mohamed Ahmedna (2012) Functions/applications of trypsin in food processing and food science research, 75-95
[3] http://www.webmd.com/vitamins-supplements/ingredientmono-879-trypsin.aspx?activeingredientid=879&activeingredientname=trypsin

Chemical Properties

White or almost white, crystalline or amorphous powder, hygroscopic if amorphous.

Uses

Proteolytic enzyme.

Uses

Trypsin is a digestive enzyme found in the digestive system. The enzyme catalyzes the hydrolysis of peptide bonds breaking down proteins into smaller peptides.

Uses

Trypsin-EDTA Solution 10X has been used to release adherent cells from tissue culture plates for passaging.

Definition

trypsin: An enzyme that digests proteins(see protease). It is secreted inan inactive form (trypsinogen) by thepancreas into the duodenum. There,trypsinogen is acted on by an enzyme(enterokinase) produced in theduodenum to yield trypsin. The activeenzyme plays an important rolein the digestion of proteins in the anteriorportion of the small intestine.It also activates other proteases inthe pancreatic juice.

brand name

Parenzyme;Trypsillin.

General Description

Trypsin is applicable for tissue disaggregation, due to its effective action and tolerance towards different cell type and serum-induced neutralization.

Biochem/physiol Actions

Trypsin cleaves peptides on the C-terminal side of lysine and arginine residues. The rate of hydrolysis of this reaction is slowed if an acidic residue is on either side of the cleavage site and hydrolysis is stopped if a proline residue is on the carboxyl side of the cleavage site. The optimal pH for trypsin activity is 7-9. Trypsin can also act to cleave ester and amide linkages of synthetic derivatives of amino acids. EDTA is added to trypsin solutions as a chelating agent that neutralizes calcium and magnesium ions that obscure the peptide bonds on which trypsin acts. Removing these ions increases the enzymatic activity. Serine protease inhibitors, including DFP, TLCK, APMSF, AEBSEF, and aprotinin, amongst others, will inhibit Trypsin.

Trypsin Preparation Products And Raw materials

Raw materials

Preparation Products

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Trypsin Suppliers

Zhuhai Gene-Biocon Biological Technology Co., Ltd.
Tel
0756-6348118 13825639916
Email
info@zhuhaigbc.com
Country
China
ProdList
20
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58
Nanjing Dulai Biotechnology Co., Ltd.
Tel
025-84699383-8003 18013301590
Fax
025-84699383-8003
Email
njduly@126.com
Country
China
ProdList
971
Advantage
55
Shanghai Baoman Biotechnology Co., Ltd.
Tel
021-62130998
Fax
021-54438215
Email
baomanbio@163.com
Country
China
ProdList
108
Advantage
55
Jiangsu Jinpu Nuoan Biotechnology Co., Ltd
Tel
0512-82709698 15250590826
Email
marketing@gproan.com.cn
Country
China
ProdList
8
Advantage
58
Chongqing Peg-Bio Biopharm Co., Ltd.
Tel
+86-18302355932 +86-18302355932
Email
ly@pegbiocq.com
Country
China
ProdList
10
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
Advantage
55
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View Lastest Price from Trypsin manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Trypsin 9002-07-7
Price
US $0.00/KG
Min. Order
1KG
Purity
2500ups u/mg
Supply Ability
500kg/month
Release date
2021-07-23
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Trypsin 9002-07-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-15
HebeiShuoshengImportandExportco.,Ltd
Product
Trypsin 9002-07-7
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08

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