ChemicalBook > CAS DataBase List > Chymotrypsin

Chymotrypsin

Product Name
Chymotrypsin
CAS No.
9004-07-3
Chemical Name
Chymotrypsin
Synonyms
α-Chymotrypsin;A-CHYMOTRYPSIN;EC 3.4.21.1;ALPHA-CHYMOTRYPSIN;zolyse;zolyes;D03484;chymar;ec3445;ec3446
CBNumber
CB4167554
Molecular Formula
N/A
Formula Weight
0
MOL File
Mol file
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Chymotrypsin Property

Melting point:
127°C
Density 
1.37[at 20℃]
vapor pressure 
0Pa at 25℃
storage temp. 
-20°C
solubility 
Reconstitute in 1mM HCl. Soluble at 10mg/ml in 1mM HCl. 2mM calcium chloride serves as a stabilizer. Store aliquoted solutions at -20°C for up to a week.
form 
salt-free, lyophilized powder
color 
white
Water Solubility 
125g/L at 25℃
Merck 
13,2282
LogP
-1.3 at 20℃
EPA Substance Registry System
Chymotrypsin (9004-07-3)
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Safety

Hazard Codes 
Xn,B
Risk Statements 
36/37/38-42/43-42
Safety Statements 
26-36-36/37-24-22
WGK Germany 
3
RTECS 
GC3050000
3-10
TSCA 
Yes
HS Code 
35079090
Hazardous Substances Data
9004-07-3(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SRP6509
Product name
Chymotrypsin from human pancreas
Purity
≥95% (SDS-PAGE)
Packaging
100μg
Price
$428
Updated
2024/03/01
Sigma-Aldrich
Product number
CHY5S
Product name
α-Chymotrypsin from bovine pancreas
Purity
≥40?units/mgprotein,vialof5?mg
Packaging
10vials
Price
$310
Updated
2024/03/01
Sigma-Aldrich
Product number
C9134
Product name
α-Chymotrypsin−Agarose from bovine pancreas
Purity
lyophilized powder, 2,000-3,500?units/g agarose (One ml gel will yield 65-120?units)
Packaging
50units
Price
$327
Updated
2024/03/01
Sigma-Aldrich
Product number
C9134
Product name
α-Chymotrypsin−Agarose from bovine pancreas
Purity
lyophilized powder, 2,000-3,500?units/g agarose (One ml gel will yield 65-120?units)
Packaging
100units
Price
$582
Updated
2024/03/01
Sigma-Aldrich
Product number
C8946
Product name
α-Chymotrypsin from human pancreas
Purity
lyophilized powder
Packaging
1VIAL
Price
$688
Updated
2024/03/01
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Chymotrypsin Chemical Properties,Usage,Production

Chemical Properties

Lyophilized powder, dialyzed

Uses

α-Chymotrypsin from bovine has been used in a study to inform proteasome inhibition in order to advance anticancer research. α-Chymotrypsin from bovine has also been used in a study that functionalized surface anchored poly(methylhydrosiloxane) thin films on oxidized silicon wafers.

Uses

The enzyme from Sigma has been used to assess the effect of limited proteolysis with α-chymotrypsin on the sperm penetration.

Uses

α-Chymotrypsin from bovine pancreas has been used in a study to investigate protein extraction by Winsor-III microemulsion systems. α-Chymotrypsin from bovine pancreas has also been used in a study to investigate a new specific fullerene-based fluorescent probe for trypsin.

General Description

Chymotrypsin (Chymar) is extractedfrom mammalian pancreas and is used in cataractsurgery. A dilute solution is used to irrigate the posteriorchamber of the eye to dissolve the fine filaments that holdthe lens.

Biochem/physiol Actions

α-Chymotrypsin is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. Molecular weight of this enzyme is found to be 25 kDa. Its pI is 8.75. It selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan, and leucine. Ca2+ activates and stabilizes the enzyme. The enzyme is inhibited by diisopropyl fluorophosphate (DFP), phenylmethanesulfonyl fluoride (PMSF), N-p-tosyl-L-phenylalanine chloromethyl ketone (TPCK), chymostatin, aprotinin, α1-antitrypsin, α2-macroglobulin, 10 mM Cu2+ and Hg2+.

Purification Methods

α-Chymotrypsin is crystallised twice from four-tenths saturated ammonium sulfate solution, then dissolved in 1mM HCl and dialysed against 1mM HCl at 2-4o. The solution is stored at 2o [Lang et al. J Am Chem Soc 80 4923 1958].

Chymotrypsin Preparation Products And Raw materials

Raw materials

Preparation Products

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Chymotrypsin Suppliers

Gansu Tiansen Pharmaceutical Co., Ltd.
Tel
0938-2888585
Fax
NULL
Email
tiansen2711806@126.com
Country
China
ProdList
5
Advantage
58
Shanghai Baoman Biotechnology Co., Ltd.
Tel
021-62130998
Fax
021-54438215
Email
baomanbio@163.com
Country
China
ProdList
105
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3576
Advantage
66
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
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View Lastest Price from Chymotrypsin manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Chymotrypsin 9004-07-3
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98.0%
Supply Ability
1kg/month
Release date
2021-08-26
Hebei Lingding Biotechnology Co., Ltd.
Product
Chymotrypsin 9004-07-3
Price
US $78.00-65.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
9000kg/per week
Release date
2021-08-20
Handan Tongyi New Material Technology Co., Ltd
Product
Chymotrypsin 9004-07-3
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99.9%
Supply Ability
8000kgs/month
Release date
2021-03-15

9004-07-3, ChymotrypsinRelated Search:


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