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AVICULARIN

Product Name
AVICULARIN
CAS No.
572-30-5
Chemical Name
AVICULARIN
Synonyms
QUERCETIN-3-ARABINOSIDE;Quercetin 3-α-L-arabinofuranoside;AVICULARIN;Fenicularin;Avicularoside;Avicularin-RM;common Knotgrass Herb;Avicularin (6CI, 7CI, 8CI);3α-Hydroxy-5β-cholanic acid;QUERCETIN-3-ARABINOSIDE hplc
CBNumber
CB2753735
Molecular Formula
C20H18O11
Formula Weight
434.35
MOL File
572-30-5.mol
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AVICULARIN Property

Melting point:
207-208 °C
Boiling point:
855.4±65.0 °C(Predicted)
Density 
1.86±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly, Sonicated), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form 
Solid
pka
6.17±0.40(Predicted)
color 
Pale Yellow to Light Yellow
Stability:
Hygroscopic
InChI
InChI=1/C20H18O11/c21-8-4-11(24)14-13(5-8)30-18(7-1-2-9(22)10(23)3-7)19(16(14)27)31-20-17(28)15(26)12(25)6-29-20/h1-5,12,15,17,20-26,28H,6H2/t12-,15-,17+,20?/s3
InChIKey
PZZRDJXEMZMZFD-TTYPJOBMNA-N
SMILES
C1(OC2=C(C(O)=CC(O)=C2)C(=O)C=1OC1OC[C@H](O)[C@H](O)[C@H]1O)C1C=CC(O)=C(O)C=1 |&1:17,19,21,r|
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
44006
Product name
Avicularin
Purity
analytical standard
Packaging
5mg
Price
$484
Updated
2022/05/15
Usbiological
Product number
299977
Product name
Avicularin
Packaging
20mg
Price
$575
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
74061
Product name
Avicularin
Purity
98%
Packaging
20mg
Price
$567
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001311
Product name
AVICULARIN
Purity
98.00%
Packaging
10MG
Price
$1155
Updated
2021/12/16
Biosynth Carbosynth
Product number
FQ65464
Product name
Quercetin-3-arabinoside
Packaging
1mg
Price
$65
Updated
2021/12/16
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AVICULARIN Chemical Properties,Usage,Production

Chemical Properties

Pale yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from Saururus chinensis (Lour.) Baill.

Uses

Quercetin-3-arabinoside can be used to prevent or treat degenerative brain disease.

Definition

ChEBI: A quercetin O-glycoside in which an alpha-L-arabinofuranosyl residue is attached at position 3 of quercetin via a glycosidic linkage. It is isolated particularly from Juglans regia and ital Foeniculum vulgare.

in vivo

Avicularin (injected in articular cavity of the knee, 0.5-2 mg/kg, twice a week for 4 weeks) attenuates the development of OA (osteoarthritis) in ACLT-induced rats[4].
? Avicularin (oral administration, 50 and 100 mg/kg, for 21 days) attenuates memory Impairment in rats with amyloid Beta-induced Alzheimer's disease[5].

Animal Model:ACLT (anterior cruciate ligament transection)-induced rats[4]
Dosage:0.5, 1, 2 mg/kg
Administration:Injected into the articular cavity of the right knee, twice a week for 4 weeks.
Result:Alleviated the tibial subchondral osteolysis, reduces bone loss, and increases the bone mass of tibial subchondral bone.
Attenuated ECM degradation, the loss of Aggrecan and Collagen II in ACLT-induced rats.
Decreased the MMP3 and MMP13 protein level.
Animal Model:Rats with amyloid Beta-induced Alzheimer's disease[5]
Dosage:25, 50, and 100 mg/kg
Administration:Oral administration, for 21 days
Result:Enhanced cognition activity, and reversed the effects of amyloid beta-induced inflammatory response and excessive oxidative stress.

IC 50

GLUT4; PPARγ; COX-2

AVICULARIN Preparation Products And Raw materials

Raw materials

Preparation Products

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AVICULARIN Suppliers

China 184 Germany 1 India 1 Japan 1 United Kingdom 7 United States 19 USA 1 Global 214
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View Lastest Price from AVICULARIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Avicularin 572-30-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-16
Shanghai Standard Technology Co., Ltd.
Product
Avicularin 572-30-5
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-16
Zhuozhou Wenxi import and Export Co., Ltd
Product
avicularin 572-30-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

572-30-5, AVICULARINRelated Search:

Trypsin Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) 4',5-DIHYDROXY-7-METHOXYFLAVONE ISOQUERCITRIN hydroxygenkwanin Quercetin-7-O-β-D-glucopyranoside MOSLOFLAVONE PONCIRIN GARDENIN B 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one FRIEDELAN-3BETA-OL AVICULARIN(SH) 2'-O-GALLOYLHYPERIN Hyperoside SYRINGETIN-3-GALACTOSIDE AVICULARIN MYRICETIN 3-O-L-ARABINOPYRANOSIDE MYRICETIN-3-GALACTOSIDE

  • AVICULARIN
  • QUERCETIN-3-ARABINOSIDE
  • Avicularoside
  • Fenicularin
  • 3-(α-L-Arabinofuranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
  • Quercetin 3-α-L-arabinofuranoside
  • Avicularin(Quercetin 3-alpha-L-arabinofuranoside)
  • QUERCETIN-3-ARABINOSIDE hplc
  • Quercetin 3-O-α-L-arabinofuranoside
  • 3,3′,4′,5,7-Pentahydroxyflavone 3-O-α-L-arabinofuranoside
  • Avicularin, 98%, from Polygonum aviculare L.
  • 4H-1-Benzopyran-4-one, 3-(α-L-arabinofuranosyloxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-
  • 3-[(2S,3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
  • 3α-Hydroxy-5β-cholanic acid
  • Avicularin (6CI, 7CI, 8CI)
  • 3-(((2S,3R,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
  • common Knotgrass Herb
  • Avicularin-RM
  • 572-30-5
  • Flavanols
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract