ChemicalBook > CAS DataBase List > AC-IEPD-PNA
AC-IEPD-PNA
- Product Name
- AC-IEPD-PNA
- CAS No.
- 216757-29-8
- Chemical Name
- AC-IEPD-PNA
- Synonyms
- AC-IEPD-PNA;AC-ILE-GLU-PRO-ASP-PNA;AC-ILE-GLU-PRO-ASP-PARANITROANILIDE;N-ACETYL-ILE-GLU-PRO-ASP-P-NITROANILINE;N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide;GRANZYME B SUBSTRATE VIII, COLORIMETRIC;N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide;N-ACETYL-ILE-GLU-PRO-ASP-P-NITROANILIDE;AC-IETD-PNA;L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-nitrophenyl)- (9CI)
- CBNumber
- CB2762317
- Molecular Formula
- C28H38N6O11
- Formula Weight
- 634.63
- MOL File
- 216757-29-8.mol
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AC-IEPD-PNA Property
- Boiling point:
- 1096.9±65.0 °C(Predicted)
- Density
- 1.386±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 4.06±0.10(Predicted)
- color
- White to off-white
- Sequence
- Ac-Ile-Glu-Pro-Asp-{pNA}
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- A6470
- Product name
- N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide
- Purity
- ≥97% (HPLC), powder
- Packaging
- 5MG
- Price
- $455
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 368067-M
- Product name
- Granzyme B Substrate VIII, Colorimetric
- Purity
- A colorimetric substrate for granzyme B (kcat</sub>/Km</sub> = 6.6 x 10⁴ M⁻¹s⁻¹).
- Packaging
- 1 unit
- Price
- $141
- Updated
- 2025/07/31
Biosynth Carbosynth
- Product number
- FA110813
- Product name
- Ac-Ile-Glu-Pro-Asp-pNA
- Packaging
- 2mg
- Price
- $118
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110813
- Product name
- Ac-Ile-Glu-Pro-Asp-pNA
- Packaging
- 5mg
- Price
- $236
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2152CJ
- Product name
- Ac-Ile-Glu-Pro-Asp-PNA
- Packaging
- 5mg
- Price
- $368
- Updated
- 2021/12/16
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AC-IEPD-PNA Chemical Properties,Usage,Production
Uses
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide (Ac-IEPD-pNA) is a granzyme B substrate that allows accurate measurement of granzyme B activity[1].
Biological Activity
Primary Target
Colorimetric substrate for granzyme B', 'kcat/Km = 6.6 x 104 M-¹ sec-¹ as substrate for granzyme B
References
[1] Kristina Fritsch, et al. Suppression of granzyme B activity and caspase-3 activation in leukaemia cells constitutively expressing the protease inhibitor 9. Ann Hematol. 2013 Dec;92(12):1603-9. DOI:10.1007/s00277-013-1846-6
AC-IEPD-PNA Preparation Products And Raw materials
Raw materials
Preparation Products
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