ChemicalBook > CAS DataBase List > 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE

Product Name
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
CAS No.
162012-70-6
Chemical Name
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
Synonyms
4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE;4-chloro-6-nitro-7-fluoro-quinazoline;Quinazoline, 4-chloro-7-fluoro-6-nitro-;4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE###162012-70-6;Afatinib impurity 6: 4-chloro-7fluoro-6-nitroquinazoline
CBNumber
CB2765398
Molecular Formula
C8H3ClFN3O2
Formula Weight
227.58
MOL File
162012-70-6.mol
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4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Property

Boiling point:
395℃
Density 
1.649
Flash point:
193℃
storage temp. 
Sealed in dry,Store in freezer, under -20°C
pka
0.53±0.70(Predicted)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C376255
Product name
4-Chloro-7-fluoro-6-nitroquinazoline
Packaging
25mg
Price
$125
Updated
2021/12/16
TRC
Product number
C376255
Product name
4-Chloro-7-fluoro-6-nitroquinazoline
Packaging
1g
Price
$655
Updated
2021/12/16
Matrix Scientific
Product number
093430
Product name
4-Chloro-7-fluoro-6-nitroquinazoline
Purity
95+%
Packaging
250mg
Price
$341
Updated
2021/12/16
Matrix Scientific
Product number
093430
Product name
4-Chloro-7-fluoro-6-nitroquinazoline
Purity
95+%
Packaging
1g
Price
$756
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0062821
Product name
4-CHLORO-7-FLUORO-6-NITROQUINAZOLINE
Purity
95.00%
Packaging
1G
Price
$924
Updated
2021/12/16
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4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Chemical Properties,Usage,Production

Uses

4-Chloro-7-fluoro-6-nitroquinazoline is an intermediate in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Suppliers

China 145 Germany 1 India 2 United Kingdom 1 United States 8 Global 157
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View Lastest Price from 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
4-Chloro-7-fluoro-6-nitroquinazoline 162012-70-6
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-09-13
ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
Afatinib impurity 17 162012-70-6
Price
US $0.00-0.00/mg
Min. Order
10mg
Purity
98%
Supply Ability
500mg
Release date
2024-06-05
Hebei Kingfiner Technology Development Co.Ltd
Product
4-chloro-6-nitro-7-fluoro-quinazoline, 162012-70-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000kg
Release date
2023-12-07

162012-70-6, 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINERelated Search:

4-CHLORO-6-NITROQUINAZOLINE 4-chloro-7-fluoro-quinazoline 4-CHLOROQUINAZOLIN-6-AMINE Afatinib impurity 30 Afatinib Impurity 22 Afatinib Impurity L (Afatinib N-Oxide) Afatinib Impurity 9 Afatinib IMpurity H Afatinib Impurity 74 Afatinib impurity 40 Afatinib impurity 33 Afatinib Impurity 14 TRANS-4-AMINOCROTONIC ACID 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE Afatinib Impurity 17 Afatinib Impurity 4 Afatinib IMpurity E Afatinib Impurity 6

  • 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE
  • 4-CHLORO-7-FLUORO-6-NITRO-QUINAZOLINE###162012-70-6
  • 4-chloro-6-nitro-7-fluoro-quinazoline
  • Afatinib impurity 6: 4-chloro-7fluoro-6-nitroquinazoline
  • Quinazoline, 4-chloro-7-fluoro-6-nitro-
  • 162012-70-6
  • 16292-70-6
  • C8H3ClFN3O2