Desonide

Product Name: Desonide
CAS No.: 638-94-8
Chemical Name: Desonide
Synonyms: Tridesilon;PREDNACINOLONE;d-2083;Topifug;The Ned;DESONIDE;Locapred;Desonade;steroderm;Be Consolide
CBNumber: CB2783466
Molecular Formula: C24H32O6
Formula Weight: 416.51
MOL File: 638-94-8.mol

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Desonide Property

Melting point:: 272-274?C
Boiling point:: 580.1±50.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMF (Slightly, Sonicated), DMSO (Sparingly), Methanol (Slightly, Heated)
form: Solid
pka: 12.87±0.10(Predicted)
color: White to Off-White
CAS DataBase Reference: 638-94-8(CAS DataBase Reference)

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Safety

HS Code: 2937290000
Toxicity: LD50 in rats (mg/kg): 93 s.c. (Phillips)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P314Get medical advice/attention if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS021596
Product name: Desonide
Packaging: 50MG
Price: $37.8
Updated: 2022/05/15

TCI Chemical

Product number: D5578
Product name: Desonide
Packaging: 250MG
Price: $27
Updated: 2024/03/01

TCI Chemical

Product number: D5578
Product name: Desonide
Packaging: 1G
Price: $75
Updated: 2024/03/01

Cayman Chemical

Product number: 21368
Product name: Desonide
Purity: ≥98%
Packaging: 50mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 21368
Product name: Desonide
Purity: ≥98%
Packaging: 100mg
Price: $176
Updated: 2024/03/01

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Desonide Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Originator

Tridesilon,Dome,US,1972

Uses

Desonide(Budesonide EP Impurity F) is an impurity of Budesonide (B689490), an anti-inflammatory.

Uses

antifungal

Uses

Anti-inflammatory. Desonide has also been found as an impurity in budesonide (B689490).

Definition

ChEBI: Triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.

Indications

Desonide (DesOwen, Tridesilon) is a synthetic corticosteroid.

Manufacturing Process

Preparation of 11β,21-Dihydroxy-16α,17α-Isopropylidenedioxy-1,4- Pregnadiene-3,20-Dione: A solution of 11β,16α,17α,21-tetrahydroxy-1,4- pregnadiene-3,20-dione (40 mg) in acetone (10 ml) containing hydrochloric acid (three drops; d 1.19) is boiled 3n the steam bath for two minutes and then allowed to stand for eighteen hours at room temperature. The reaction mixture is diluted with water (50 ml) and extracted with chloroform (3x25 ml), the combined extracts then being washed with water (30 ml) and dried over anhydrous sodium sulfate. The residue obtained by removal of solvent crystallized from ethyl acetate-petroleum ether as small plates (25 mg), melting point 257°-260°C.

brand name

Desowen (Galderma); Tridesilon (Perrigo).

Therapeutic Function

Antiinflammatory

Desonide Preparation Products And Raw materials

Raw materials

Preparation Products

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Desonide Suppliers

Americas 1 Belgium 2 Brazil 1 Canada 3 China 356 Europe 3 France 1 Germany 3 India 40 Israel 2 Italy 2 Japan 1 Malaysia 1 Nepal 1 Philippines 1 South Korea 1 United Kingdom 8 United States 41 Venezuela 1 Global 469

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View Lastest Price from Desonide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Desonide 638-94-8
Price: US $0.00/g
Min. Order: 10g
Purity: 97.0-103.0%,USP30
Supply Ability: 50kg/month
Release date: 2021-06-19

Wuhan Senwayer Century Chemical Co.,Ltd

Product: Desonide 638-94-8
Price: US $380.00/gram
Min. Order: 100gram
Purity: 99% HPLC
Supply Ability: 20 tons
Release date: 2022-10-21

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Desonide 638-94-8
Price: US $70.00-700.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-06

638-94-8, DesonideRelated Search:

(r)-budesonide Ciclesonide 11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 14,15-Dehydro Budesonide 9α-BroMobudesonide 16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-hoMoandrosta-1,4-diene-3,17a-dione (Mixture of DiastereoMers) LY2228820 Meprednisone Dienogestrel Clopidogrel Bisulfate LY 2157299 Budesonide Di-Norbudesonide (Mixture of DiastereoMers) 9,11-Anhydrobudesonide 21-Acetoxy-11β-hydroxy-16α,17α-propylmethylenedioxpregna-1,4-diene-3,20-dione (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione 1,2-Dehydrobudesonide Budesonide Sulfate SodiuM (Mixture of DiastereoMers)

PREDNACINOLONE

DESONIDE

1,4-PREGNADIEN-11-BETA, 16-ALPHA, 17,21-TETROL-3,20-DIONE 16,17-ACETONIDE

(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione

16-alpha-hydroxyprednisole-16,17-acetonide

17-acetonide,16-alpha-hydroxy-prednisolone-1

d-2083

steroderm

Desonidemicro

(11β,16α)-11,21-Dihydroxy-16,17-[(1-Methylethylidene)bis(oxy)]pregna -1,4-diene-3,20-dione

16α-Hydroxyprednisolone Acetonide

(11,16a)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

16a-Hydroxyprednisolone Acetonide

Locapred

Topifug

Tridesilon

Be Consolide

16a-Hydroxyprednisole-16,17-acetonide

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11b,16a)-

Desonide (250 mg)

Desonide, >=99%

Budesonide EP Impurity F(Desonide)

16α,17-[1-methylethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione

Budesonide impurity F

Budesonide Impurity F (Desonide)

DesonideBiocar

Budesonide Impurity 6(Budesonide EP Impurity F)

Budesonide iMpurit F

Budesonide EP Impurity F

11beta,21-Dihydroxy-16alpha,17alpha-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-

Desonide Solution in Acetonitrile, 100μg/mL

(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

(11beta,16alpha)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione

Budesonide Acetonide

Desonide USP/EP/BP

DesonideQ: What is Desonide Q: What is the CAS Number of Desonide Q: What is the storage condition of Desonide

16a,17-[1-Methylethylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

Desonide (1173304)

The Ned

-Amino-2-methyl-283H-tetrazole

Desonide (Budesonide acetonide)

API Steriods Desonide Powder Dosage Usage Effect and Benefit

16α,17-[1-methylethylidenebis(oxy)]-11β,21-dihydroxypregna-1,4-diene-3,20-dione

Pregna-1,4-diene-3,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11β,16α)-

Desonide (Budesonide EP Impurity F)

1, 4-PREGNADIEN-11β, 16α, 17, 21-TETROL-3, 20-DIONE 16, 17-ACETONIDE

Desonide/(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

Desonade

(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

Desonide/(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

Desonide EP Impurity-E

16alpha,17-[1-Methylethylidenebis(oxy)]-11beta,21-dihydroxypregna-1,4-diene-3,20-dione (Desonide)

638-94-8

C24H32O6

SPORANOX

Hormone Drugs

Chiral Reagents