6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)

Product Name: 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)
CAS No.: 134-47-4
Chemical Name: 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)
Synonyms: H)-dione;phosgenated;Urea J Acid;-bicarbazole;AMI-1,freeacid;-tetrasulfonic Acid;J ACID UREA, FREE ACID;Scarletacidlowsodiumsalt;-Tetrabromo bisphenol a 99+%;-Methylenebis-1,3-benzodioxol-5-ol
CBNumber: CB2855268
Molecular Formula: C21H16N2O9S2
Formula Weight: 504.49
MOL File: 134-47-4.mol

More

Less

6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) Property

Density: 1.798±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO: 83.33 mg/mL (165.18 mM)
pka: -0.17±0.40(Predicted)
form: Solid
color: Light brown to brown
CAS DataBase Reference: 134-47-4(CAS DataBase Reference)
EPA Substance Registry System: 7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid] (134-47-4)

More

Less

Safety

TSCA: TSCA listed

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P285In case of inadequate ventilation wear respiratory protection.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P403Store in a well-ventilated place.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C177258
Product name: 7,7''-(Carbonylbis(azanediyl))bis(4-hydroxynaphthalene-2-sulfonicacid)
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Usbiological

Product number: 162198
Product name: 6,6'-
Packaging: 10mg
Price: $460
Updated: 2021/12/16

ChemScene

Product number: CS-0010165
Product name: AMI-1(freeacid)
Purity: ≥98.0%
Packaging: 5mg
Price: $90
Updated: 2021/12/16

Matrix Scientific

Product number: 076104
Product name: 7,7'-(Carbonylbis(azanediyl))bis(4-hydroxynaphthalene-2-sulfonic acid)
Purity: 95+%
Packaging: 1g
Price: $116
Updated: 2021/12/16

AK Scientific

Product number: M145
Product name: Scarletacid
Packaging: 25g
Price: $134
Updated: 2021/12/16

More

Less

6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) Chemical Properties,Usage,Production

Uses

7,7''-(Carbonylbis(azanediyl))bis(4-hydroxynaphthalene-2-sulfonic acid) (cas# 134-47-4) is a pharmacologically active compound capable of selective nonbisphosphonate inhibition of human geranylgeranyl diphosphate synthase, and inhibition of shikimate dehydrogenase and shikimate kinase in shikimate pathway of Helicobacter pylori.

Preparation

7,7' -Urylenebis(4-hydroxynaphthalene-2- sulfonic acid) [134-47-4] , J acid urea, carbonyl J acid, is produced by reacting the sodium salt of J acid with phosgene in aqueous solution at 30℃ and maintaining alkalinity with sodium carbonate. After being heated to 80℃, the product is salted out with sodium chloride (yield ca. 100 %). It is used to produce C.I. Direct Orange 26; C.I. Direct Reds 4, 14, 23, and 80; and C.I. Direct Brown 112.

in vivo

AMI-1 free acid (0.5 mg; intratumorally; daily; for 7 days) inhibits S180 viability in vivo^[4].
AMI-1 free acid (0.5 mg; intratumorally; daily; for 7 days) downregulates PRMT5 but does not regulate the expression of PRMT7 in a tumor xenograft model^[4].
AMI-1 free acid (0.5 mg; intratumorally; daily; for 7 days) decreases the levels of H4R3me2s and H3R8me2s in a tumor xenograft model^[4].

Animal Model:	6-7 weeks old male Kunming mice (18-22 g), with S180 cells xenograft^[4]
Dosage:	0.5 mg
Administration:	Intratumorally, daily, for 7 days
Result:	Decreased tumor weight.

6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) Preparation Products And Raw materials

Raw materials

Sodium bisulfite Sodium metabisulfite

Preparation Products

trisodium [mu-[2-[[1-hydroxy-6-[[[[5-hydroxy-6-[(2-hydroxy-5-sulphophenyl)azo]-7-sulpho-2-naphthyl]amino]carbonyl]amino]-3-sulpho-2-naphthyl]azo]benzoato(7-)]]dicuprate(3-) Direct Red 23 Direct Orange S Leather Black Copper, 2,2'-[carbonylbis[imino(1-hydroxy-3-sulfo-6,2-naphthalenediyl)azo]]bis[benzoic acid] complex tetrasodium [mu-[[7,7'-(carbonyldiimino)bis[4-hydroxy-3-[(2-hydroxy-5-sulphophenyl)azo]naphthalene-2-sulphonato]](8-)]]dicuprate(4-)

More

Less

6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) Suppliers

China 115 Europe 1 India 2 Singapore 1 United Kingdom 2 United States 14 USA 1 Global 136

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8667
Advantage: 57

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9747
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

BePharm Ltd

Tel: 400-685-9117
Fax: 021-51816740
Email: market@bepharm.com
Country: China
ProdList: 15081
Advantage: 60

More

Less

View Lastest Price from 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) 134-47-4
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-18

Hebei Chuanghai Biotechnology Co., Ltd

Product: Scarlet acid 134-47-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-29

Hebei Yanxi Chemical Co., Ltd.

Product: Scarlet acid 134-47-4
Price: US $60.00-9.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 25 tons
Release date: 2023-09-06

134-47-4, 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)Related Search:

Imidazolidinyl urea CALCIUM DODECYLBENZENE SULFONATE Dodecylbenzenesulphonic acid Molasses CHLOROPHOSPHONAZO III Linear alkyl benzenesulphonate 1-DODECANESULFONIC ACID SODIUM SALT Naphthalene Solvent Red 43 Sodium N-cyclohexylsulfamate Disodium 7,7'-(carbonyldiimino)bis(4-hydroxynaphthalene-2-sulphonate) LINEAR ALKYLBENZENE SULPHONIC ACID DIRECT RED 80 CALCOMINE ORANGE 2RS Direct Red 23 DIRECT RED 83 DIRECT ORANGE 26 6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid)

4,4'-dihydroxy-7,7'-ureylenedi(naphthalene-2-sulphonic acid)

7,7'-(Carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic acid]

6,6'-ureylene-bis(1-naphthol-3-sulfonic acid)

phosgenated

N,N'-bis(4-hydroxy-2-sulfonaphthalene-7-yl)urea

7,7'-Ureylenebis(4-hydroxy-2-naphthalenesulfonic acid)

N,N'-Bis[6-(1-naphthol-3-sulfonic acid)]urea

6,6'-ureylenbis-1-naphthol-3-sulfonic acid

7,7'-(Carbonylbisimino)bis(4-hydroxynaphthalene-2-sulfonic acid)

4-hydroxy-7-[(5-hydroxy-7-sulfo-2-naphthyl)carbamoylamino]naphthalene-2-sulfonic acid

4-hydroxy-7-[(5-hydroxy-7-sulfo-naphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonic acid

4-hydroxy-7-[(5-hydroxy-7-sulfonaphthalen-2-yl)carbamoylamino]naphthalene-2-sulfonic acid

7,7'-(Carbonylbis(azanediyl))bis(4-hydroxynaphthalene-2-sulfonic acid)

2-Naphthalenesulfonic acid, 7,7-(carbonyldiimino)bis4-hydroxy-

J ACID UREA, FREE ACID

66UREYLENEBIS1NAPHTHOL3SULPHONICACIDDISODIUMSALT

7,7'-(carbonyldiimino)bis[4-hydroxy-2-naphthalenesulfonic aci

AMI-1,freeacid

-Ureylene-bis(1-naphthol-3-sulfonic acid)

-(Iminosulfonyloxy)bis[6-deoxy-1,2:3,4-bis-O-(1-methylethylidene)-&alpha

-Tetrakis(methoxymethoxy)-indigotin

-diyl)bis(oxy))bis(3,5-diiodo-4,1-phenylene))bis(2-aminopropanoic Acid)

-Oxybis(4,6-dihydro-2H-furo[3,2-c]pyran-2-one)

H)-dione

-Tetrakis(methoxymethoxy)-indigotin N-Isopropyl

-((1s,3s,5r,7r)-Adamantane-1,3-diylbis(4-methoxy-3,1-phenylene))bis(2-naphthoic Acid Diethyl Ester

-Trehalose Dimycolate (Cord-Factor, TDM)

-Tetrabromo bisphenol a 99+%

-Methylenebis-1,3-benzodioxol-5-ol

-bicarbazole

-tetrasulfonic Acid

6,6'-Ureylene-bis(1-naphthol-3-sulfonic acid) ISO 9001：2015 REACH

Urea J Acid

4,4'-dihydroxy-7,7'-ureylenedi(naphthalene-2-sulphonic acid

5,5-Dihydroxy-2,2-Dinaphthyl Urea-7,7 Disulfonic Acid

Scarletacidlowsodiumsalt

134-47-4

134-47-7

C21H16N2O9S2

Intermediates of Dyes and Pigments