ChemicalBook > CAS DataBase List > Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-

Product Name
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
CAS No.
70209-81-3
Chemical Name
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
Synonyms
Component B1b;Ivermectin B1b;IvermectinH2B1b;avermectin H2B1b;Dihydroavermectin B1b;22,23-Dihydroavermectin B1b;22,23- dihydroavermectin B1b (Ivermectin B1b);22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
CBNumber
CB2918291
Molecular Formula
C47H72O14
Formula Weight
861.07
MOL File
70209-81-3.mol
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Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Property

Boiling point:
934.1±65.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
pka
12.42±0.70(Predicted)
Stability:
Temperature sensitive
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Safety

RIDADR 
2588
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23824
Product name
Ivermectin B1b
Purity
≥95%
Packaging
500μg
Price
$311
Updated
2024/03/01
Cayman Chemical
Product number
23824
Product name
Ivermectin B1b
Purity
≥95%
Packaging
2.5mg
Price
$1316
Updated
2024/03/01
TRC
Product number
I940825
Product name
IvermectinB1b
Packaging
2.5mg
Price
$1220
Updated
2021/12/16
Usbiological
Product number
D3570-04A
Product name
Ivermectin B1b
Packaging
500ug
Price
$478
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0017173
Product name
B1-BETA-IVERMECTIN COMPONENT
Purity
95.00%
Packaging
5MG
Price
$501.15
Updated
2021/12/16
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Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Chemical Properties,Usage,Production

Uses

Ivermectin B1b is a minor component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.

Uses

Ivermectin B1b (dihydroavermectin B1b) is the minor component (<20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro, the B1b (25-iso-propyl) analogue is slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis, and also a more sensitive probe for ivermectin resistance.

Definition

ChEBI: A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin.

brand name

Stromectol (Merck).

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Suppliers

ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396
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0755-28363542
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sales@chem-strong.com
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China
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17994
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Beijing Jin Ming Biotechnology Co., Ltd.
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010-60605840 18892239720
Fax
010-60605840
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psaitong@jm-bio.com
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China
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Lynnchem
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86-(0)29-85992781 17792393971
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info@lynnchem.com
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China
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Novachemistry
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Fax
(0)2080432064
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United Kingdom
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Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
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sales@rrkchem.com
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China
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55896
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BOC Sciences
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+16314854226
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inquiry@bocsci.com
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United States
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19743
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Hubei Jusheng Technology Co.,Ltd.
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18871490254
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027-59599243
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linda@hubeijusheng.com
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CHINA
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28180
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Jinan blalong chemical co. LTD
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2710913286@.com
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1513643261@qq.com
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China
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14253
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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China
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11289
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View Lastest Price from Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- manufacturers

Career Henan Chemical Co
Product
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- 70209-81-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-99.9%
Supply Ability
100kg
Release date
2020-01-10

70209-81-3, Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-Related Search:


  • Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
  • avermectin H2B1b
  • Component B1b
  • 22,23-Dihydro-34-nor-5-O-demethylavermectin A1a
  • 22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
  • 22,23-Dihydroavermectin B1b
  • Dihydroavermectin B1b
  • 5-O-Demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a
  • Ivermectin B1b
  • IvermectinH2B1b
  • DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b
  • 22,23- dihydroavermectin B1b (Ivermectin B1b)
  • 70209-81-3