ChemicalBook > CAS DataBase List > Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-

Product Name
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
CAS No.
70209-81-3
Chemical Name
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
Synonyms
Component B1b;Ivermectin B1b;IvermectinH2B1b;avermectin H2B1b;Dihydroavermectin B1b;22,23-Dihydroavermectin B1b;22,23- dihydroavermectin B1b (Ivermectin B1b);22,23-Dihydro-34-nor-5-O-demethylavermectin A1a;DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b;22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
CBNumber
CB2918291
Molecular Formula
C47H72O14
Formula Weight
861.07
MOL File
70209-81-3.mol
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Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Property

Boiling point:
934.1±65.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
pka
12.42±0.70(Predicted)
Stability:
Temperature sensitive
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Safety

RIDADR 
2588
HazardClass 
6.1(a)
PackingGroup 
II
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23824
Product name
Ivermectin B1b
Purity
≥95%
Packaging
500μg
Price
$311
Updated
2024/03/01
Cayman Chemical
Product number
23824
Product name
Ivermectin B1b
Purity
≥95%
Packaging
2.5mg
Price
$1316
Updated
2024/03/01
TRC
Product number
I940825
Product name
IvermectinB1b
Packaging
2.5mg
Price
$1220
Updated
2021/12/16
Usbiological
Product number
D3570-04A
Product name
Ivermectin B1b
Packaging
500ug
Price
$478
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0017173
Product name
B1-BETA-IVERMECTIN COMPONENT
Purity
95.00%
Packaging
5MG
Price
$501.15
Updated
2021/12/16
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Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Chemical Properties,Usage,Production

Uses

Ivermectin B1b is a minor component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.

Uses

Ivermectin B1b (dihydroavermectin B1b) is the minor component (<20%) of the commercial anthelmintic, ivermectin. Members of the avermectin/milbemycin anthelmintic class exert their anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. The avermectin/milbemycins are also potent insecticides. In vitro, the B1b (25-iso-propyl) analogue is slightly more potent than the 25-sec-butyl (B1a) analogue as an inhibitor of nematode larval development and paralysis, and also a more sensitive probe for ivermectin resistance.

Definition

ChEBI: A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin.

brand name

Stromectol (Merck).

Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- Suppliers

China 32 India 4 United Kingdom 1 United States 6 Global 43
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
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58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52925
Advantage
58
Cayman Chemical Company
Tel
--
Fax
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Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
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Email
chemicals@usbio.net
Country
United States
ProdList
6214
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80
MedChemExpress
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Email
sales@medchemexpress.com
Country
United States
ProdList
6398
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View Lastest Price from Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- manufacturers

Career Henan Chemical Co
Product
Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)- 70209-81-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-99.9%
Supply Ability
100kg
Release date
2020-01-10

70209-81-3, Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-Related Search:

Acetamiprid Pymetrozine theta-Cypermethrin Cyhalothrin Avermectin A1a, 5-O-demethyl-22,23-dihydro- 28-Oxo IverMectin B1a (IMpurity) 2-Methyltetrahydropyran rac-2,3-Dehydro-3,4-dihydro IverMectin IverMectin B1 Aglycon Ivermectin Avermectin B1a aglycone delta2-Avermectin B1a Abamectin Avermectin B1a monosaccharide 8,9-Z-AVERMECTINB1A Avermectin B1b Avermectin B1a 8a-oxo-avermectin B1a

  • Avermectin A1a, 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)-
  • avermectin H2B1b
  • Component B1b
  • 22,23-Dihydro-34-nor-5-O-demethylavermectin A1a
  • 22,23-Dihydro-5-O-demethyl-25-de(1-methylpropyl)-25-isopropylavermectin A1a
  • 22,23-Dihydroavermectin B1b
  • Dihydroavermectin B1b
  • 5-O-Demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a
  • Ivermectin B1b
  • IvermectinH2B1b
  • DihydroaverMectin B1b, 22,23-DihydroaverMectin B1b
  • 22,23- dihydroavermectin B1b (Ivermectin B1b)
  • 70209-81-3