ChemicalBook > CAS DataBase List > 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride

Product Name
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride
CAS No.
35604-67-2
Chemical Name
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride
Synonyms
Viloxazine HCl;Viloxazine hydrochloride;Vivalan;Vicilan;Vivilan;Vivarint;Catatrol;ICI-58834;Viloxazin Hydrochloride;Adrenaline Impurity 43-13C6
CBNumber
CB2933621
Molecular Formula
C13H20ClNO3
Formula Weight
273.7558
MOL File
35604-67-2.mol
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2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Property

Melting point:
178-180°C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
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Safety

HazardClass 
IRRITANT
Toxicity
LD50 in mice (mg/kg): 1000 orally, 60 i.v. (Brosnan)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
V312440
Product name
racViloxazineHydrochloride
Packaging
1mg
Price
$155
Updated
2021/12/16
TRC
Product number
V312440
Product name
racViloxazineHydrochloride
Packaging
10mg
Price
$1230
Updated
2021/12/16
Matrix Scientific
Product number
058070
Product name
2-((2-Ethoxyphenoxy)methyl)morpholinehydrochloride
Purity
95%
Packaging
500mg
Price
$229
Updated
2021/12/16
Matrix Scientific
Product number
058070
Product name
2-((2-Ethoxyphenoxy)methyl)morpholinehydrochloride
Purity
95%
Packaging
1g
Price
$352
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0304667
Product name
2-((2-ETHOXYPHENOXY)METHYL)MORPHOLINE HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$505.68
Updated
2021/12/16
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2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Originator

Vivalan,I.C.I. ,UK,1974

Uses

Rac Viloxazine Hydrochloride is research useful chemical used as an antidepressant.

Manufacturing Process

2-Ethoxyphenol is first reacted with epichlorohydrin to give 1,2-epoxy-3-(o- ethoxyphenoxy)-propane.
A mixture of crude (83%) 1,2-epoxy-3-(o-ethoxyphenoxy)propane (19.4 grams), 70.5 grams 2-aminoethyl hydrogen sulfate, 40.0 grams sodium hydroxide, 400 ml ethanol and 200 ml water is stirred at 60°C for 18 hours and is then evaporated to dryness. The residue is dissolved in 200 ml water and the mixture is extracted three times with 150 ml of diethyl ether each time. The combined extracts are dried over magnesium sulfate and evaporated to dryness, The crude product (21.5 grams) is dissolved in isopropanol (20 ml), 10.5 ml concentrated aqueous hydrochloric acid and 75 ml ethyl acetate are added and the mixture is cooled. The mixture is filtered and there is thus obtained as solid product 2-(o-ethoxyphenoxymethyl) morpholine hydrochloride, MP 179° to 182°C (8.6 grams; 38% yield based on total epoxide used), according to US Patent 3,712,890.

Therapeutic Function

Psychotropic

2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride Suppliers

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View Lastest Price from 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride 35604-67-2
Price
US $8.00-0.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08

35604-67-2, 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochlorideRelated Search:

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  • Morpholine, 2-(2-ethoxyphenoxy)methyl-, hydrochloride
  • ICI-58834
  • Vivalan
  • Viloxazine hydrochloride
  • rac Viloxazine Hydrochloride
  • 2-[(2-ethoxyphenoxy)methyl]morpholine hydrochloride
  • (+/-)-2-(o-EthoxyphenoxyMethyl)Morpholine
  • Catatrol
  • Vicilan
  • Viloxazin Hydrochloride
  • Vivarint
  • Vivilan
  • Viloxazine HCl
  • Viloxazine hydrochloride salt
  • 2-[(2-Ethoxy phenoxy)methyl]morpholine HCl
  • Adrenaline Impurity 43-13C6
  • 35604-67-2
  • C13H19NO3HCl
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals