3-Bromo-L-phenylalanine

Uses

Product Name: 3-Bromo-L-phenylalanine
CAS No.: 82311-69-1
Chemical Name: 3-Bromo-L-phenylalanine
Synonyms: L-3-Br-phe;L-3-BR-PHE-OH;3-Br-L-Phe-OH;L-Phe(3-Br)-OH;RRSYY(Avadomide)-5;(L)-Bromophenyl alanine;m-Bromo-L-phenylalanine;3-Bromo-L-phenylalanine;L-Phenylalanine, 3-bromo-;3-Bromo-L-phenylalanine,95%
CBNumber: CB2948139
Molecular Formula: C9H10BrNO2
Formula Weight: 244.09
MOL File: 82311-69-1.mol

More

Less

3-Bromo-L-phenylalanine Property

Boiling point:: 368.4±32.0 °C(Predicted)
Density: 1.588±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 2.16±0.10(Predicted)
form: solid
color: White to off white
optical activity: Consistent with structure
Water Solubility: Slightly soluble in water.

More

Less

Safety

HS Code: 2922498590

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Usbiological

Product number: 265342
Product name: 3-Bromo- L-phenylalanine
Packaging: 1g
Price: $379
Updated: 2021/12/16

TRC

Product number: B789320
Product name: 3-Bromo-L-phenylalanine
Packaging: 250mg
Price: $40
Updated: 2021/12/16

TRC

Product number: B789320
Product name: 3-Bromo-L-phenylalanine
Packaging: 1g
Price: $65
Updated: 2021/12/16

Activate Scientific

Product number: AS39494
Product name: (S)-2-Amino-3-(3-bromophenyl)propanoic acid
Purity: 98% ee
Packaging: 5G
Price: $67
Updated: 2021/12/16

ChemScene

Product number: CS-W008183
Product name: 3-Bromo-L-phenylalanine
Purity: 99.80%
Packaging: 10g
Price: $70
Updated: 2021/12/16

More

Less

3-Bromo-L-phenylalanine Chemical Properties,Usage,Production

Uses

3-Bromo-L-phenylalanine is used in preparation of lifitegrast intermediate.

Chemical Properties

White to off-white powder

Uses

It is applied in the facile removal of leader peptides from lanthipeptides by incorporation of a hydroxy acid.

Uses

3-Bromo-L-phenylalanine is used in preparation of lifitegrast intermediate.

Synthesis

82278-73-7

82311-69-1

The general procedure for the synthesis of (S)-2-amino-3-(3-bromophenyl)propionic acid from (S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propionic acid was as follows: (S)-3-(3-bromophenyl)-2-((tert-butoxycarbonyl)amino)propionic acid (5.0 g, 14.5 mmol) was suspended in a 1,4-dioxane solution of 4 M hydrochloric acid (75 mL ) and the reaction was stirred at room temperature for 16 hours. Upon completion of the reaction, the white precipitate was collected by filtration and washed with ether (Et2O) to afford (S)-2-amino-3-(3-bromophenyl)propionic acid (3.2 g, 89% yield) as a white solid, and the product did not require further purification. The nuclear magnetic resonance hydrogen spectrum (1H NMR, CDCl3) data of the product were as follows: δ 8.32 (2H, s), 7.50-7.48 (2H, m), 7.34-7.29 (2H, m), 4.22 (1H, t, J=6.2 Hz), 3.13-3.11 (2H, m).

References

[1] Patent: WO2008/47109, 2008, A1. Location in patent: Page/Page column 42
[2] Patent: WO2006/114606, 2006, A1. Location in patent: Page/Page column 61

3-Bromo-L-phenylalanine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-Bromo-L-phenylalanine Suppliers

China 162 Germany 1 India 1 United Kingdom 3 United States 9 Global 176

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Shanghai HC Biotech Co., Ltd

Tel: 021-20227858
Fax: +86-21-20227857
Email: sale@hcbiotech.com.cn
Country: China
ProdList: 1095
Advantage: 55

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Suzhou haiyu Biochem Industrial Co., LTD

Tel: 512-68097639 18013585858
Fax: 0512-
Email: 744942877@qq.com
Country: China
ProdList: 915
Advantage: 62

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

More

Less

View Lastest Price from 3-Bromo-L-phenylalanine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-Bromo-L-phenylalanine 82311-69-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Career Henan Chemical Co

Product: 3-Bromo-L-phenylalanine 82311-69-1
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-07-30

82311-69-1, 3-Bromo-L-phenylalanineRelated Search:

(2S)-2-amino-3-(3-carbamoylphenyl)propanoic acid L-3-Chlorophenylalanine FMOC-D-4-THIAZOLYLALANINE L-3-Cyanophenylalanine L-3-AMINOMETHYLPHE 4-Bromo-D-phenylalanine, N-BOC protected,N-alpha-t-Butyloxycarbonyl-4-bromo-D-phenylalanine,BOC-4-BROMO-D-PHENYLALANINE,BOC-P-BROMO-D-PHENYLALANINE FMOC-3-BROMO-L-PHENYLALANINE BOC-3-BROMO-L-PHENYLALANINE 2-BROMO-L-PHENYLALANINE BOC-(R)-4-BROMO-BETA-PHENYLALANINE FMOC-(S)-4-BROMO-BETA-PHENYLALANINE BOC-(S)-4-BROMO-BETA-PHENYLALANINE FMOC-2-BROMO-L-PHENYLALANINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2-BROMO-L-PHENYLALANINE 3-BROMO-DL-PHENYLALANINE 4-BROMO-D-PHENYLALANINE BOC-2-BROMO-L-PHENYLALANINE BOC-2-BROMO-D-PHENYLALANINE 4-BROMO-DL-PHENYLALANINE,4-Bromo-DL-phenylalanine, 98+%

3-Bromo-L-phenylalanine

(S)-2-Amino-3-(3'-Bromophenyl)Propanoic Acid

(L)-Bromophenyl alanine

3-Br-L-Phe-OH

(S)-2-((3-bromophenyl)amino)propanoic acid

L-Phe(3-Br)-OH

m-Bromo-L-phenylalanine

L-3-BR-PHE-OH

L-3-Br-phe

L-Phenylalanine, 3-bromo-

3-Bromo-L-phenylalanine,95%

3-Bromo-L-phenylalanine USP/EP/BP

RRSYY(Avadomide)-5

82311-69-1

Amino Acid Derivatives

Amino Acids