5-Hydroxy-1-methylpyrazole
- Product Name
- 5-Hydroxy-1-methylpyrazole
- CAS No.
- 33641-15-5
- Chemical Name
- 5-Hydroxy-1-methylpyrazole
- Synonyms
- 1-methyl-1H-pyrazol-5-ol;1-Methyl-1H-pyrazol-3(2H)-one;33641-15-5;Topramezon-001;1-Methylpyrazol-5-ol;2-methylpyrazol-3-ol;-Methyl-1H-pyrazol-5-ol;2-Methyl-2H-pyrazol-3-ol;1-methyl-5-hydroxypyrazol;1-Methyl-5-hydroxypyrazole
- CBNumber
- CB2971487
- Molecular Formula
- C4H6N2O
- Formula Weight
- 98.1
- MOL File
- 33641-15-5.mol
5-Hydroxy-1-methylpyrazole Property
- Melting point:
- 110-114 °C
- Boiling point:
- 217.7±13.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- soluble in DMSO, Methanol
- form
- powder to crystal
- pka
- 9.07±0.23(Predicted)
- color
- White to Orange to Green
- InChI
- InChI=1S/C4H6N2O/c1-6-4(7)2-3-5-6/h2-3,7H,1H3
- InChIKey
- CMXOTACIOGGSNH-UHFFFAOYSA-N
- SMILES
- N1(C)C(O)=CC=N1
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-37/38-41
- Safety Statements
- 26-39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 747831
- Product name
- 5-Hydroxy-1-methyl-1H-pyrazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $104
- Updated
- 2023/06/20
- Product number
- H1695
- Product name
- 5-Hydroxy-1-methyl-1H-pyrazole
- Packaging
- 1G
- Price
- $65
- Updated
- 2025/07/31
- Product number
- H1695
- Product name
- 5-Hydroxy-1-methyl-1H-pyrazole
- Packaging
- 5G
- Price
- $217
- Updated
- 2025/07/31
- Product number
- H948380
- Product name
- 5-Hydroxy-1-methylpyrazole
- Packaging
- 5g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- 4H01-1-1R
- Product name
- 1-Methyl-1H-pyrazol-5-ol
- Purity
- 97%
- Packaging
- 10g
- Price
- $184
- Updated
- 2021/12/16
5-Hydroxy-1-methylpyrazole Chemical Properties,Usage,Production
Uses
5-Hydroxy-1-methylpyrazole is a pyrazole derivative used as an intermediate in the preparation of herbicides.
Synthesis
88398-78-1
33641-15-5
The general procedure for the synthesis of 1-methyl-5-hydroxypyrazole-4-carboxylic acid from ethyl 1-methyl-5-hydroxypyrazole-4-carboxylate is as follows: 22 g of sodium hydroxide was dissolved in 300 mL of water, 42.5 g of intermediate (ethyl 1-methyl-5-hydroxypyrazole-4-carboxylate) was added, and the reaction was stirred for 3 hr at 40 °C, then cooled to room temperature. 55 mL of concentrated hydrochloric acid was added dropwise, followed by heating and refluxing for 3 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure, 200 mL of anhydrous ethanol was added to the residue, and the precipitate was collected by filtration after thorough stirring. The filtrate was concentrated under reduced pressure to give 24 g of white solid product (1-methyl-5-hydroxypyrazole) in 98.0% yield and 96.50% HPLC purity.
References
[1] Patent: CN105218449, 2016, A. Location in patent: Paragraph 0063; 006=5
5-Hydroxy-1-methylpyrazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Hydroxy-1-methylpyrazole manufacturers
- Product
- 5-Hydroxy-1-methylpyrazole 33641-15-5
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 20TON
- Release date
- 2024-12-11
- Product
- 5-Hydroxy-1-Methylpyrazole 33641-15-5
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-14
- Product
- 5-Hydroxy-1-methylpyrazole 33641-15-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-15