N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

ChemicalBook > CAS DataBase List > N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

Product Name: N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate
CAS No.: 212333-72-7
Chemical Name: N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate
Synonyms: HOTT;HOTTU;N,N,N',N'-Tetramethy;HOTT N,N,N'',N''-TETR;S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuron;N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuron;S-(1-OXIDO-2-PYRIDYL)-N,N,N',N'-TETRAMETHYLTHIURONIUM-PF6;N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafl...;-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate;N,N,N',N'-TetraMethyl-S-(1-oxido-2-pyridyl)thiuronhexafluorophosphate
CBNumber: CB2972338
Molecular Formula: C10H16N3OS.F6P
Formula Weight: 371.28
MOL File: 212333-72-7.mol

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N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate Property

Melting point:: 120-125 °C
storage temp.: -20°C
solubility: acetonitrile, CH2Cl2, THF (moderate solubility)
form: Powder
color: White to yellow
Sensitive: Moisture Sensitive
InChIKey: UCOGEMMJHLHOAW-UHFFFAOYSA-N
CAS DataBase Reference: 212333-72-7(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 94624
Product name: S-(1-Oxido-2-pyridyl)-N,N,N′,N′-tetramethylthiuronium hexafluorophosphate
Purity: ≥95.0%(NMR)
Packaging: 5G
Price: $144
Updated: 2023/01/07

Sigma-Aldrich

Product number: 94624
Product name: S-(1-Oxido-2-pyridyl)-N,N,N′,N′-tetramethylthiuronium hexafluorophosphate
Purity: ≥95.0%(NMR)
Packaging: 25g
Price: $682
Updated: 2023/01/07

TCI Chemical

Product number: T2821
Product name: N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $60
Updated: 2024/03/01

Alfa Aesar

Product number: H54277
Product name: S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuronium hexafluorophosphate, 98+%
Packaging: 1g
Price: $22.3
Updated: 2023/06/20

Alfa Aesar

Product number: H54277
Product name: S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuronium hexafluorophosphate, 98+%
Packaging: 5g
Price: $81.8
Updated: 2023/06/20

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N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate Chemical Properties,Usage,Production

Chemical Properties

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate is white to pale brown crystalline powder

Uses

N,N,N’N’Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is a reagent used in the preparation of hindered Barton esters from hindered carboxylic acid precursors. N,N,N’N’Tetramethy l-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is also used as a coupling reagents for peptide bond formations and amidation reactions.

Uses

N,N,N’,N’-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is a reagent used in the preparation of hindered Barton esters from hindered carboxylic acid precursors. N,N,N’,N’-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is also used as a coupling reagents for peptide bond formations and amidation reactions.

reaction suitability

reaction type: Coupling Reactions

Synthesis

S-(1-Oxido-2-pyridinyl)-1,1,3,3-tetramethylthiouronium Hexafluorophosphate (HOTT) can be prepared by slowly adding Et3N to a dry CH2Cl2 solution of 2-mercaptopyridine-N-oxide and tetramethylchloroformamidinium hexafluorophosphate. After the removal of CH2Cl2 from the reaction mixture, the resulting solid mass is pulverized, washed with CHCl3, and then filtered to give a white solid of sufficient purity to be used in subsequent reactions.

Precautions

It is advised to protect the solid from prolonged exposure to light since 2- mercaptopyridine N-oxide and related compounds can be light-sensitive.

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate 212333-72-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: N,N,N",N"-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate 212333-72-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: N,N,N",N"-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate 212333-72-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

212333-72-7, N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphateRelated Search:

Potassium hexafluorophosphate 2,4,6-Collidine 4-Methylpyridine Lithium hexafluorophosphate Hexafluorophosphoric acid 2,6-Lutidine Azamethiphos Tetramethylthiourea HPTDP 2-PYRIDYLTHIOUREA Hott(S-(1-Oxo-2-Pyridyl)-Thio-N,N,N'N'-TetramethyluroniumHexafluorophosphate) N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

S-(1-OXIDO-2-PYRIDYL)-N,N,N',N'-TETRAMETHYLTHIURONIUM-PF6

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuron

S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuron

HOTT N,N,N'',N''-TETRAMETHYL-S-(1-OXIDO-2-PYRIDYL)THIURONIUM HEXAFLUOROPHOSPHATE

HOTT

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

S-(1-Oxido-2-pyridyl)-thio-N,N,N,N-tetramethyluronium hexafluorophosphate

S-(2-Pyridyl)-N,N,Nμ,Nμ-tetramethylthiuronium N-oxide hexafluorophosphate, N,N,Nμ,Nμ-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

2-((dimethylamino)(dimethyliminio)methylthio)pyridine 1-oxide hexafluorophosphate(V)

S-(1-Oxido-2-pyridinyl) 1,1,3,3-tetramethylthiouronium hexafluorophosphate

HOTTU

N,N,N',N'-Tetramethy

S-(1-Oxido-2-pyridyl)-N,N,N,N-tetramethylthiuronium hexafluorophosphate R)

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronhexafluorophosphate (HOTT)

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate

HOTT N,N,N'',N''-TETR

N,N,N',N'-TetraMethyl-S-(1-oxido-2-pyridyl)thiuronhexafluorophosphate

S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetraMethylthiuroniuM hexafluorophosphate, 98+%

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium hexafluorophosphate≥ 98%(HPLC)

-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

[dimethylamino-[(1-oxido-2H-pyridin-6-yl)thio]methylidene]-dimethylammonium hexafluorophosphate

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate USP/EP/BP

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafl...

Methanaminium, (dimethylamino)dimethyl[(1-oxido-2-pyridinyl)thio]-, hexafluorophosphate(1-) (1:1)

(dimethylamino)dimethyl[(1-oxido-2-pyridinyl)thio]-Methanaminium hexafluorophosphate(1-) (1:1)

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate

HOTTN,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

212333-72-7

12333-72-7

C10H17F6N3OPS

C10H16F6N3O3PS

C10H16F6N3OPS

C10H16F6N3POS

C10H16N3OSF6P

Coupling Reagent