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2-CHLORO-4-METHOXYPHENOL

Product Name
2-CHLORO-4-METHOXYPHENOL
CAS No.
18113-03-6
Chemical Name
2-CHLORO-4-METHOXYPHENOL
Synonyms
2-CHLORO-4-METHOXYPHENOL;3-CHLORO-4-HYDROXYANISOLE;2-chloro-4-methoxylphenol;Phenol, 2-chloro-4-methoxy-;2-Chloro-4-methoxyphenol,97%;2-Chloro-4-methoxyphenol >2-Chloro-4-Methoxyphenol, 97% 5GR;2-Chlorohydroquinonemonomethylether;3-Chloro-4-hydroxyanisole, 2-Chloro-p-guaiacol
CBNumber
CB3100611
Molecular Formula
C7H7ClO2
Formula Weight
158.58
MOL File
18113-03-6.mol
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2-CHLORO-4-METHOXYPHENOL Property

Melting point:
41-44 °C(lit.)
Boiling point:
241°C (rough estimate)
Density 
1.153 g/mL at 25 °C(lit.)
Flash point:
185 °F
storage temp. 
Sealed in dry,2-8°C
form 
Crystalline Low Melting Solid
pka
8.98±0.18(Predicted)
Specific Gravity
1.153
color 
White to light yellow
BRN 
1936412
CAS DataBase Reference
18113-03-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29071990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
412007
Product name
2-Chloro-4-methoxyphenol
Purity
98%
Packaging
5g
Price
$73.2
Updated
2023/01/07
TCI Chemical
Product number
C1487
Product name
2-Chloro-4-methoxyphenol
Purity
>98.0%(GC)
Packaging
5g
Price
$154
Updated
2025/07/31
TCI Chemical
Product number
C1487
Product name
2-Chloro-4-methoxyphenol
Purity
>98.0%(GC)
Packaging
25g
Price
$540
Updated
2025/07/31
TRC
Product number
C596683
Product name
2-Chloro-4-methoxyphenol
Packaging
250mg
Price
$45
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK100642
Product name
2-Chloro-4-methoxyphenol
Purity
97%
Packaging
5g
Price
$51
Updated
2021/12/16
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2-CHLORO-4-METHOXYPHENOL Chemical Properties,Usage,Production

Chemical Properties

WHITE TO LIGHT YELLOW CRYST. LOW MELTING SOLID

Synthesis

935-50-2

18113-03-6

General procedure for the synthesis of 2-chloro-4-methoxyphenol from 4,4-dimethoxycyclohexa-2,5-dien-1-one: 4,4-dimethoxycyclohexa-2,5-dien-1-one (1.0 mmol) was added to the reaction vessel, followed by the addition of a solution of 1,4-dioxane in 4N HCl (0.5 mL, 2 mmol) dropwise. The yellow color of the reaction mixture faded rapidly. After completion of the reaction, the solvent was removed by vacuum evaporation. The residue was diluted with ethyl acetate (10 mL) and washed with saturated aqueous NaHCO3 solution (5 mL). The organic layer was dried with anhydrous Na2SO4, filtered and concentrated to give 2-chloro-4-methoxyphenol in 95% yield. If necessary, it can be purified by column chromatography using ethyl acetate/hexane gradient elution.

References

[1] Organic and Biomolecular Chemistry, 2014, vol. 12, # 18, p. 2854 - 2858
[2] Tetrahedron Letters, 2016, vol. 57, # 1, p. 15 - 19

2-CHLORO-4-METHOXYPHENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-4-METHOXYPHENOL Suppliers

Matrix Fine Chemicals GmbH
Tel
--
Fax
--
Email
nfo@matrix-fine-chemicals.com
Country
Switzerland
ProdList
6968
Advantage
58
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from 2-CHLORO-4-METHOXYPHENOL manufacturers

Career Henan Chemical Co
Product
2-CHLORO-4-METHOXYPHENOL 18113-03-6
Price
US $2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customise
Release date
2018-08-09

18113-03-6, 2-CHLORO-4-METHOXYPHENOLRelated Search:


  • 3-CHLORO-4-HYDROXYANISOLE
  • 2-CHLORO-4-METHOXYPHENOL
  • 2-Chlorohydroquinonemonomethylether
  • 2-Chloro-4-methoxyphenol,97%
  • 2-chloro-4-methoxylphenol
  • 2-Chloro-4-Methoxyphenol, 97% 5GR
  • 3-Chloro-4-hydroxyanisole, 2-Chloro-p-guaiacol
  • 2-Chloro-4-methoxyphenol &gt
  • Phenol, 2-chloro-4-methoxy-
  • 18113-03-6
  • C7H7ClO2
  • ClC6H3OCH3OH
  • Building Blocks
  • Oxygen Compounds
  • Phenols
  • Organic Building Blocks
  • Aromatic Hydrocarbons (substituted) & Derivatives
  • Phenol&Thiophenol&Mercaptan
  • Anisoles, Alkyloxy Compounds & Phenylacetates
  • Chlorine Compounds
  • Phenols
  • Organic Building Blocks
  • Oxygen Compounds