5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER

Product Name: 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
CAS No.: 30766-12-2
Chemical Name: 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
Synonyms: H57157;methyl 5-hydroxypicolinate;Methyl 5-hydroxypyridine-...;Methyl 5-hydroxy-2-picolinate;Methyl 5-hydroxypyridine-2-ca;Methyl 5-hydroxypyridine-2-carboxylate;5-HDROXY-PYRIDINE-2-CARBOXYLIC ACID METHY;Methyl 5-hydroxypyridine-2-carboxylate ,97%;Methyl 5-hydroxypyridine-2-carboxylate 95+%;5-Hydroxy-2-pyridinecarboxylic acid methyl ester
CBNumber: CB31010807
Molecular Formula: C7H7NO3
Formula Weight: 153.14
MOL File: 30766-12-2.mol

More

Less

5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Property

Melting point:: 193.5-195.5℃
Boiling point:: 374.2±22.0 °C(Predicted)
Density: 1.287±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
form: solid
pka: 8.29±0.10(Predicted)
color: Pale yellow

More

Less

Safety

Risk Statements: 20/21/22
Safety Statements: 24/25-36/37
HS Code: 29333990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B585303
Product name: methyl5-hydroxypyridine-2-carboxylate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Usbiological

Product number: 455730
Product name: methyl 5-hydroxypyridine-2-carboxylate
Packaging: 100mg
Price: $305
Updated: 2021/12/16

ChemScene

Product number: CS-W005963
Product name: Methyl5-hydroxypyridine-2-carboxylate
Purity: 99.76%
Packaging: 10g
Price: $210
Updated: 2021/12/16

Oakwood

Product number: 070001
Product name: 5-Hydroxy-pyridine-2-carboxylicacidmethylester
Packaging: 25g
Price: $415
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 34903
Product name: Methyl5-hydroxypyridine-2-carboxylate
Packaging: 1000mg
Price: $600
Updated: 2021/12/16

More

Less

5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Chemical Properties

Yellow solid

Uses

Methyl 5-hydroxypyridine-2-carboxylate is a phenolic acid that can found in the stems of Mahonia fortune. Methyl 5-hydroxypyridine-2-carboxylate exhibits NO inhibitory effects in vitro[1].

Synthesis

67-56-1

15069-92-8

30766-12-2

1. add methanol (70 mL) to 5-hydroxypyridine-2-carboxylic acid (5.01 g, 36.0 mmol). 2. sulfuric acid (5.8 mL, 110 mmol) was added slowly and dropwise to the above mixture. 3. The reaction mixture was stirred overnight at 75 °C. 4. 4. Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure. 5. 5. The residue was dissolved in ethyl acetate (EtOAc). 6. 6. Saturated aqueous sodium bicarbonate (NaHCO?) is added to the solution and the pH is adjusted to 3. 7. 7. The precipitate was collected by filtration and dried under vacuum. 8. 8. The remaining aqueous phase was extracted with ethyl acetate. 9. The organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate (Na?SO?). 10. The organic phases were concentrated under pressure to give the solid product methyl 5-hydroxy-2-pyridinecarboxylate (5.3 g, 96% yield), which could be used for subsequent reactions without further purification. 11. LCMS analysis: calculated value C?H?NO?([M+H]?) m/z = 154.1; measured value: 154.1.

References

[1] Liu L, et, al. Simultaneous characterisation of multiple Mahonia fortunei bioactive compounds in rat plasma by UPLC-MS/MS for application in pharmacokinetic studies and anti-inflammatory activity in vitro. J Pharm Biomed Anal. 2020 Feb 5;179:113013. DOI:10.1016/j.jpba.2019.113013

5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER Suppliers

China 125 Germany 1 India 1 United Kingdom 1 United States 14 Global 142

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

More

Less

View Lastest Price from 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 30766-12-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-14

Career Henan Chemical Co

Product: 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 30766-12-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200KG
Release date: 2018-12-23

30766-12-2, 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTERRelated Search:

tert-butyl 5-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate TERT-BUTYL 5-HYDROXYHEXAHYDRO-1H-ISOINDOLE-2(3H)-CARBOXYLATE 5-Hydroxypyrimidine METHYL-5-METHOXY-2-METHYLBENZOATE 1,2,3,4-TETRAHYDRO-ISOQUINOLIN-5-OL 5-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE 5-HYDROXY-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE Ethyl 5-hydroxypyrazine-2-carboxylate 5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER methyl 6-bromo-5-hydroxy-2-pyridinecarboxylate Picolinic acid, 5-(p-chlorophenoxy)-, 5-indanyl ester methyl 5-(allyloxy)-6-bromo-2-pyridinecarboxylate 2-Pyridinecarboxylic acid, 5-(2-(trifluoromethyl)phenoxy)-, 2,3-dihydr o-1H-inden-5-yl ester METHYL 2-BENZYL-7-HYDROXY-1,3-DIOXO-2,3-DIHYDRO-1H-PYRROLO[3,4-C]PYRIDINE-4-CARBOXYLATE Methyl 6-amino-5-hydroxy-2-pyridinecarboxylate methyl 6-bromo-5-[(3-methylbenzyl)oxy]-2-pyridinecarboxylate methyl 6-bromo-5-methoxy-2-pyridinecarboxylate Methyl 5,6-dihydroxypicolinate

Methyl 5-hydroxypyridine-2-carboxylate 95+%

H57157

Methyl 5-hydroxypyridine-2-carboxylate ,97%

Methyl 5-hydroxypyridine-2-carboxylate

5-Hydroxy-2-pyridinecarboxylic acid methyl ester

Methyl 5-hydroxypyridine-...

Methyl 5-hydroxypicolinate, 5-Hydroxy-2-(methoxycarbonyl)pyridine

methyl 5-hydroxypicolinate

2-Pyridinecarboxylic acid, 5-hydroxy-, methyl ester

5-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER ISO 9001：2015 REACH

5-HDROXY-PYRIDINE-2-CARBOXYLIC ACID METHY

2-Pyridinecarboxylic acid, 5-hydroxy-, methyl ester (9CI, ACI)

5-hydroxy-2-Pyridinecarboxylic acid methyl ester (9CI ACI)

Methyl 5-hydroxy-2-picolinate

Methyl 5hydroxypyridine2carboxylate,acid,Inhibitor,inhibit,Methyl 5 hydroxypyridine 2 carboxylate,phenolic

5-Hydroxy-pyridin-2-carboxylic acid methyl ester

Methyl 5-hydroxypyridine-2-ca

Methyl 5-hydroxypyridine-2-carboxylate, 10 mM in DMSO

30766-12-2