ChemicalBook > CAS DataBase List > Nestoron

Nestoron

Product Name
Nestoron
CAS No.
7759-35-5
Chemical Name
Nestoron
Synonyms
ST 1435;NESTORON;NESTORONE;Elcometrine;Nestorone Acetate;Nestoron (ST-1435);Norgestone acetate;Segesterone Acetate;ELCOMETRINE;NESTORONE;ST-1435;ST1435;ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435
CBNumber
CB31011778
Molecular Formula
C23H30O4
Formula Weight
370.48
MOL File
7759-35-5.mol
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Nestoron Property

Melting point:
178-179°
alpha 
D21 -105° (c = 1.2 in chloroform)
Boiling point:
420.37°C (rough estimate)
Density 
1.0550 (rough estimate)
refractive index 
1.4433 (estimate)
storage temp. 
2-8°C
solubility 
DMSO: soluble5mg/mL, clear
form 
powder
color 
white to beige
InChIKey
CKFBRGLGTWAVLG-GOMYTPFNSA-N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H351Suspected of causing cancer

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0550
Product name
Nestorone
Purity
≥97% (HPLC)
Packaging
10mg
Price
$96.1
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0550
Product name
Nestorone
Purity
≥97% (HPLC)
Packaging
50mg
Price
$372
Updated
2024/03/01
Cayman Chemical
Product number
26441
Product name
Segesterone Acetate
Packaging
10mg
Price
$78
Updated
2024/03/01
Cayman Chemical
Product number
26441
Product name
Segesterone Acetate
Packaging
25mg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
26441
Product name
Segesterone Acetate
Packaging
5mg
Price
$44
Updated
2024/03/01
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Nestoron Chemical Properties,Usage,Production

Uses

Segesterone Acetate has been used to study the: comparison of androgenic and estrogenic properties of progestins used in contraception and hormone therapy; impact on hepatic estrogen-sensitive proteins by 1-yr contraceptive vaginal ring delivering Nestorone and ethinyl estradiol.

Definition

ChEBI: Elcometrine is a corticosteroid hormone.

Pharmacokinetics

Elcometrine is a member of the 19-norprogesterone class of pr ogestins. when administered subcuta neously (implant), intravaginally (vaginal ring), or transdermally, elcometrine is an exceptionally potent progestin. It is 100-fold more potent when administered subcutaneously than when delivered orally. Its oral bioavaiability is only 10%,with a half life of just 1 to 2 hours because of rapid metabolism. The C16 methylene functionality substantially increases its affinity for the progesterone receptor.

Clinical Use

Because of its antiestrogenic action, elcometrine also can be administered transdermally along with estradiol as a treatment for menopausal symptoms .

Nestoron Preparation Products And Raw materials

Raw materials

Preparation Products

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Nestoron Suppliers

Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
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60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
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58
Alfa Chemistry
Tel
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
24072
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58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
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58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
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Protheragen-ING
Tel
+16313385890
Email
info@protheragen-ing.com
Country
United States
ProdList
3868
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
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58
ApexBio Technology
Tel
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Fax
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Email
sales@apexbt.com
Country
United States
ProdList
6251
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BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
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65
Cayman Chemical Company
Tel
--
Fax
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Email
cayman@caymanchem.com
Country
United States
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6213
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81
MedChemExpress
Tel
--
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Email
sales@medchemexpress.com
Country
United States
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Riedel-de Haen AG
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6773
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Alfa Chemistry
Tel
--
Fax
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Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
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0
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
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View Lastest Price from Nestoron manufacturers

Career Henan Chemical Co
Product
Nestoron 7759-35-5
Price
US $1.00/KG
Min. Order
1G
Purity
98%
Supply Ability
100KG
Release date
2018-08-20

7759-35-5, NestoronRelated Search:


  • ST 1435
  • NESTORONE
  • NESTORON
  • 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate
  • Elcometrine
  • 17-(ACETYLOXY)-16-METHYLENE-19-NORPREGN-4-ENE-20-DIONE
  • 16-Methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione acetate
  • 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dione
  • 19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene- (9ci)
  • 19-Norpregn-4-ene-3,20-dione, 17-hydroxy-16-methylene-, acetate
  • Nestoron (ST-1435)
  • 17-(Acetyloxy)-16-methylene-19-norpregn-4-ene-3,20-dione
  • ELCOMETRINE;NESTORONE;ST-1435;ST1435
  • Segesterone Acetate
  • (8R,9S,10R,13S,14S,17R)-17-acetyl-13-methyl-16-methylene-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
  • ELCOMETRINE; NESTORONE; ST-1435; ST 1435; ST1435
  • 19-Norpregn-4-ene-3,20-dione, 17-(acetyloxy)-16-methylene-
  • Estr-4-en-3-one,17-acetyl-17-(acetyloxy)-16-methylene-,(17α)-
  • Norgestone acetate
  • ST 1435,Inhibitor,Nestoron,ST1435,inhibit,Progesterone Receptor,NR3C3
  • Nestorone Acetate
  • 7759-35-5
  • API