Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI)
- Product Name
- Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI)
- CAS No.
- 170961-15-6
- Chemical Name
- Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI)
- Synonyms
- N-Boc-2-thiazolamine;N-Boc-2-AMinothiazole;2-(Boc-amino)thiazole,97%;2-(Boc-aMino)thiazole, 97%;1-(Boc-aMino)thiazole, 97%;CarbaMic acid, 2-thiazolyl-;2-(tert-ButoxycarbonylaMino)thiazole;2-t-butoxycarbonylamino-1,3-thiazole;2 - (tert butyl n-formate) aminothiazole;Thiazol-2-yl-carbaMic acid tert-butyl ester
- CBNumber
- CB31043665
- Molecular Formula
- C8H12N2O2S
- Formula Weight
- 200.26
- MOL File
- 170961-15-6.mol
Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI) Property
- Melting point:
- 180-185℃
- Density
- 1.242±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 5.25±0.70(Predicted)
- Appearance
- Light yellow to brown Solid
- InChI
- InChI=1S/C8H12N2O2S/c1-8(2,3)12-7(11)10-6-9-4-5-13-6/h4-5H,1-3H3,(H,9,10,11)
- InChIKey
- NCJXQSNROJRSSL-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NC1=NC=CS1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B809668
- Product name
- tert-ButylN-(1,3-Thiazol-2-yl)carbamate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B809668
- Product name
- tert-ButylN-(1,3-Thiazol-2-yl)carbamate
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 064895
- Product name
- tert-ButylThiazol-2-ylcarbamate
- Purity
- 95%
- Packaging
- 1g
- Price
- $13
- Updated
- 2021/12/16
- Product number
- CS-W015607
- Product name
- tert-Butylthiazol-2-ylcarbamate
- Purity
- 99.53%
- Packaging
- 5g
- Price
- $41
- Updated
- 2021/12/16
- Product number
- 5512AD
- Product name
- tert-ButylN-(1,3-thiazol-2-yl)carbamate
- Packaging
- 1g
- Price
- $67
- Updated
- 2021/12/16
Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI) Chemical Properties,Usage,Production
Synthesis
96-50-4
24424-99-5
170961-15-6
General procedure for the synthesis of tert-butyl thiazole-2-carbamate from 2-aminothiazole and di-tert-butyl dicarbonate: tert-butyl dicarbonate (27.5 ml, 119.9 mmol) was added to a tetrahydrofuran solution (20 ml) of 2-aminothiazole (10.0 g, 99.9 mmol) and the reaction mixture was stirred for 16 hours at room temperature. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give the crude product. The crude product was recrystallized in hexane to give tert-butyl thiazole-2-carbamate (19.25 g, 96% yield) as colorless crystals. The melting point of the product was 181.5-182.5 °C, 1H NMR (300 MHz, CDCl3) δ 1.60 (9H, s), 6.88 (1H, d, J = 3.7 Hz), 7.38 (1H, d, J = 3.7 Hz), 11.9 (1H, s); IR (Nujol) 1713 cm-1; APCI-MS m/z 201 [M + H]+.
References
[1] Organic letters, 2002, vol. 4, # 24, p. 4209 - 4212
[2] Patent: EP2103611, 2009, A1. Location in patent: Page/Page column 59-60
[3] New Journal of Chemistry, 2018, vol. 42, # 12, p. 10142 - 10147
[4] Patent: US5627198, 1997, A
[5] Patent: WO2011/58149, 2011, A1. Location in patent: Page/Page column 127
Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI) Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI) manufacturers
- Product
- Carbamic acid, 2-thiazolyl-, 1,1-dimethylethyl ester (9CI) 170961-15-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09