3,3'-Dithiobis(sulfosuccinimidylpropionate)
- Product Name
- 3,3'-Dithiobis(sulfosuccinimidylpropionate)
- CAS No.
- 81069-02-5
- Chemical Name
- 3,3'-Dithiobis(sulfosuccinimidylpropionate)
- Synonyms
- DTSSP Crosslinker;3,3'-Dithiobis(sulfosuccinimidylpropionate);DTSSP 3,3'-Dithiobis(sulfosucciniMidylpropionate);3,3Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester;3,3’-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester 90%;3,3`-Dithiobis(sulfosucciniMidylpropionate)(DTSSP(Sulfo-DSP));ADC Linkers,Inhibitor,inhibit,DTSSP Crosslinker,Antibody-drug conjugates linkers;3-Pyrrolidinesulfonic acid, 1,1'-[dithiobis[(1-oxo-3,1-propanediyl)oxy]]bis[2,5-dioxo-;1,1'-((3,3'-Disulfanediylbis(propanoyl))bis(oxy))bis(2,5-dioxopyrrolidine-3-sulfonic acid)
- CBNumber
- CB31073260
- Molecular Formula
- C14H16N2O14S4
- Formula Weight
- 564.54
- MOL File
- 81069-02-5.mol
3,3'-Dithiobis(sulfosuccinimidylpropionate) Property
- Density
- 1.94
- storage temp.
- 2-8°C
- pka
- -0.34±0.20(Predicted)
- form
- solid
- color
- Light tan
Safety
- Safety Statements
- 26-36
- HS Code
- 29309090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 803200
- Product name
- DTSSP (3,3′-dithiobis(sulfosuccinimidyl propionate))
- Packaging
- 50MG
- Price
- $212
- Updated
- 2023/06/20
- Product number
- 169675
- Product name
- DTSSP Crosslinker
- Packaging
- 50mg
- Price
- $316
- Updated
- 2021/12/16
- Product number
- 169676
- Product name
- DTSSP Crosslinker
- Packaging
- 250mg
- Price
- $621
- Updated
- 2021/12/16
- Product number
- BP-22660
- Product name
- DTSSPCrosslinker
- Purity
- 90%
- Packaging
- 500mg
- Price
- $990
- Updated
- 2021/12/16
- Product number
- BP-22660
- Product name
- DTSSPCrosslinker
- Purity
- 90%
- Packaging
- 1g
- Price
- $1485
- Updated
- 2021/12/16
3,3'-Dithiobis(sulfosuccinimidylpropionate) Chemical Properties,Usage,Production
Chemical Properties
12.0
Uses
It is a water-soluble, thiol cleavable, homobifunctional and amine-reactive crosslinking agent.
Uses
sulfhydryl reactive cleavable heterobifunctional cross-linking reagent, pyridine-2-thione release can be monitored at 343 nm after reactions with sulfhydryl groups
General Description
DTSSP is 3,3′-Dithiobis(sulfosuccinimidylpropionate), which contains an amine-reactive N-hydroxysulfosuccinimide (sulfo-NHS) ester at each end of an 8-carbon spacer arm. Sulfo-NHS esters react with primary amines at pH 7-9 to form stable amide bonds, along with release of the N-hydroxysulfosuccinimide leaving group. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for sulfo-NHS-ester crosslinking reagents. DSS, the non-sulfonated analog of DTSSP is also available for applications that require a membrane-permeable crosslinker.
3,3'-Dithiobis(sulfosuccinimidylpropionate) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,3'-Dithiobis(sulfosuccinimidylpropionate) manufacturers
- Product
- 3,3"-Dithiobis(sulfosuccinimidylpropionate) 81069-02-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 3,3"-Dithiobis(sulfosuccinimidylpropionate) 81069-02-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08