ChemicalBook > CAS DataBase List > 3,3'-Dithiobis(sulfosuccinimidylpropionate)

3,3'-Dithiobis(sulfosuccinimidylpropionate)

Product Name: 3,3'-Dithiobis(sulfosuccinimidylpropionate)
CAS No.: 81069-02-5
Chemical Name: 3,3'-Dithiobis(sulfosuccinimidylpropionate)
Synonyms: DTSSP Crosslinker;3,3'-Dithiobis(sulfosuccinimidylpropionate);DTSSP 3,3'-Dithiobis(sulfosuccinimidylpropionate);3,3Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester;3,3'-Dithiobispropionic acid bis-sulfosuccinimidyl ester;3,3’-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester 90%;3,3`-Dithiobis(sulfosucciniMidylpropionate)(DTSSP(Sulfo-DSP));ADC Linkers,Inhibitor,inhibit,DTSSP Crosslinker,Antibody-drug conjugates linkers;3-Pyrrolidinesulfonic acid, 1,1'-[dithiobis[(1-oxo-3,1-propanediyl)oxy]]bis[2,5-dioxo-;1,1'-((3,3'-Disulfanediylbis(propanoyl))bis(oxy))bis(2,5-dioxopyrrolidine-3-sulfonic acid)
CBNumber: CB31073260
Molecular Formula: C14H16N2O14S4
Formula Weight: 564.54
MOL File: 81069-02-5.mol

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3,3'-Dithiobis(sulfosuccinimidylpropionate) Property

Density: 1.94
storage temp.: 2-8°C
solubility: Water solubility > 6 mg/mL
form: solid
pka: -0.34±0.20(Predicted)
color: Light tan
Appearance: White solid
Water Solubility: soluble (>6mg/ml in water)

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Safety

Safety Statements: 26-36
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 803200
Product name: DTSSP (3,3′-dithiobis(sulfosuccinimidyl propionate))
Packaging: 50MG
Price: $228
Updated: 2025/07/31

Usbiological

Product number: 169675
Product name: DTSSP Crosslinker
Packaging: 50mg
Price: $316
Updated: 2021/12/16

Usbiological

Product number: 169676
Product name: DTSSP Crosslinker
Packaging: 250mg
Price: $621
Updated: 2021/12/16

BroadPharm

Product number: BP-22660
Product name: DTSSPCrosslinker
Purity: 90%
Packaging: 500mg
Price: $990
Updated: 2021/12/16

BroadPharm

Product number: BP-22660
Product name: DTSSPCrosslinker
Purity: 90%
Packaging: 1g
Price: $1485
Updated: 2021/12/16

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3,3'-Dithiobis(sulfosuccinimidylpropionate) Chemical Properties,Usage,Production

Chemical Properties

12.0

Uses

It is a water-soluble, thiol cleavable, homobifunctional and amine-reactive crosslinking agent.

Uses

sulfhydryl reactive cleavable heterobifunctional cross-linking reagent, pyridine-2-thione release can be monitored at 343 nm after reactions with sulfhydryl groups

General Description

DTSSP is 3,3′-Dithiobis(sulfosuccinimidylpropionate), which contains an amine-reactive N-hydroxysulfosuccinimide (sulfo-NHS) ester at each end of an 8-carbon spacer arm. Sulfo-NHS esters react with primary amines at pH 7-9 to form stable amide bonds, along with release of the N-hydroxysulfosuccinimide leaving group. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for sulfo-NHS-ester crosslinking reagents. DSS, the non-sulfonated analog of DTSSP is also available for applications that require a membrane-permeable crosslinker.

reaction suitability

reagent type: cross-linking reagent

IC 50

Disulfide Cleavable Linker; Cleavable Linker

3,3'-Dithiobis(sulfosuccinimidylpropionate) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3,3'-Dithiobis(sulfosuccinimidylpropionate) manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3,3"-Dithiobis(sulfosuccinimidylpropionate) 81069-02-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3,3"-Dithiobis(sulfosuccinimidylpropionate) 81069-02-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

81069-02-5, 3,3'-Dithiobis(sulfosuccinimidylpropionate)Related Search:

3,3'-Dithiodipropionic acid SODIUM ISOSTEAROYL-2-LACTYLATE 3,3'-Dithiobis(sulfosuccinimidylpropionate) 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

3,3'-Dithiobis(sulfosuccinimidylpropionate)

3,3’-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester 90%

3,3Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester

3,3`-Dithiobis(sulfosucciniMidylpropionate)(DTSSP(Sulfo-DSP))

DTSSP Crosslinker

3-Pyrrolidinesulfonic acid, 1,1'-[dithiobis[(1-oxo-3,1-propanediyl)oxy]]bis[2,5-dioxo-

1,1'-((3,3'-Disulfanediylbis(propanoyl))bis(oxy))bis(2,5-dioxopyrrolidine-3-sulfonic acid)

ADC Linkers,Inhibitor,inhibit,DTSSP Crosslinker,Antibody-drug conjugates linkers

3,3'-Dithiobispropionic acid bis-sulfosuccinimidyl ester

DTSSP 3,3'-Dithiobis(sulfosuccinimidylpropionate)

81069-02-5

C14H14N2Na2O14S4

Cross Linking Reagents

Homobifunctional Crosslinker