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3,3'-Dithiobis(sulfosuccinimidylpropionate)

Product Name
3,3'-Dithiobis(sulfosuccinimidylpropionate)
CAS No.
81069-02-5
Chemical Name
3,3'-Dithiobis(sulfosuccinimidylpropionate)
Synonyms
DTSSP Crosslinker;3,3'-Dithiobis(sulfosuccinimidylpropionate);3,3'-Dithiobis(sulfosuccinimidylpropionate);DTSSP 3,3'-Dithiobis(sulfosucciniMidylpropionate);DTSSP 3,3'-Dithiobis(sulfosuccinimidylpropionate);3,3Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester;3,3'-Dithiobispropionic acid bis-sulfosuccinimidyl ester;3,3’-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester 90%;3,3`-Dithiobis(sulfosucciniMidylpropionate)(DTSSP(Sulfo-DSP));ADC Linkers,Inhibitor,inhibit,DTSSP Crosslinker,Antibody-drug conjugates linkers
CBNumber
CB31073260
Molecular Formula
C14H16N2O14S4
Formula Weight
564.54
MOL File
81069-02-5.mol
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3,3'-Dithiobis(sulfosuccinimidylpropionate) Property

Density 
1.94
storage temp. 
2-8°C
pka
-0.34±0.20(Predicted)
form 
solid
color 
Light tan
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Safety

Safety Statements 
26-36
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
803200
Product name
DTSSP (3,3′-dithiobis(sulfosuccinimidyl propionate))
Packaging
50MG
Price
$212
Updated
2023/06/20
Usbiological
Product number
169675
Product name
DTSSP Crosslinker
Packaging
50mg
Price
$316
Updated
2021/12/16
Usbiological
Product number
169676
Product name
DTSSP Crosslinker
Packaging
250mg
Price
$621
Updated
2021/12/16
BroadPharm
Product number
BP-22660
Product name
DTSSPCrosslinker
Purity
90%
Packaging
500mg
Price
$990
Updated
2021/12/16
BroadPharm
Product number
BP-22660
Product name
DTSSPCrosslinker
Purity
90%
Packaging
1g
Price
$1485
Updated
2021/12/16
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3,3'-Dithiobis(sulfosuccinimidylpropionate) Chemical Properties,Usage,Production

Chemical Properties

12.0

Uses

It is a water-soluble, thiol cleavable, homobifunctional and amine-reactive crosslinking agent.

Uses

sulfhydryl reactive cleavable heterobifunctional cross-linking reagent, pyridine-2-thione release can be monitored at 343 nm after reactions with sulfhydryl groups

General Description

DTSSP is 3,3′-Dithiobis(sulfosuccinimidylpropionate), which contains an amine-reactive N-hydroxysulfosuccinimide (sulfo-NHS) ester at each end of an 8-carbon spacer arm. Sulfo-NHS esters react with primary amines at pH 7-9 to form stable amide bonds, along with release of the N-hydroxysulfosuccinimide leaving group. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for sulfo-NHS-ester crosslinking reagents. DSS, the non-sulfonated analog of DTSSP is also available for applications that require a membrane-permeable crosslinker.

3,3'-Dithiobis(sulfosuccinimidylpropionate) Preparation Products And Raw materials

Raw materials

Preparation Products

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3,3'-Dithiobis(sulfosuccinimidylpropionate) Suppliers

Canada 2 China 58 Germany 1 Japan 1 United Kingdom 1 United States 8 Global 71
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from 3,3'-Dithiobis(sulfosuccinimidylpropionate) manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
3,3"-Dithiobis(sulfosuccinimidylpropionate) 81069-02-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
3,3"-Dithiobis(sulfosuccinimidylpropionate) 81069-02-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

81069-02-5, 3,3'-Dithiobis(sulfosuccinimidylpropionate)Related Search:

SODIUM ISOSTEAROYL-2-LACTYLATE 3,3'-DITHIODIPROPIONIC ACID 3,3'-Dithiobis(sulfosuccinimidylpropionate) 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

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